BRD-A05565054_(2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)methanone_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A05565054_(2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)methanone_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABLIM1 actin binding LIM protein 1
ADM adrenomedullin
ANO1 anoctamin 1, calcium activated chloride channel
AQP9 aquaporin 9
C10ORF10 chromosome 10 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD24 CD24 molecule
CPA3 carboxypeptidase A3 (mast cell)
CREG1 cellular repressor of E1A-stimulated genes 1
CSRP1 cysteine and glycine-rich protein 1
DDIT4 DNA-damage-inducible transcript 4
EMP1 epithelial membrane protein 1
FABP7 fatty acid binding protein 7, brain
FAM107A family with sequence similarity 107, member A
FAM129A family with sequence similarity 129, member A
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GLUL glutamate-ammonia ligase
GPC3 glypican 3
HIST1H1C histone cluster 1, H1c
HK2 hexokinase 2
IL1R2 interleukin 1 receptor, type II
LPL lipoprotein lipase
MET MET proto-oncogene, receptor tyrosine kinase
MTSS1 metastasis suppressor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEG10 paternally expressed 10
POSTN periostin, osteoblast specific factor
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLPI secretory leukocyte peptidase inhibitor
SYNM synemin, intermediate filament protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPD52 tumor protein D52
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
ANKRD10 ankyrin repeat domain 10
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FASTKD5 FAST kinase domains 5
FBXO21 F-box protein 21
GSTZ1 glutathione S-transferase zeta 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXC6 homeobox C6
IGF1 insulin-like growth factor 1 (somatomedin C)
IRF8 interferon regulatory factor 8
LAMP5 lysosomal-associated membrane protein family, member 5
MIR22HG MIR22 host gene
NEFH neurofilament, heavy polypeptide
NPY neuropeptide Y
PEG3 paternally expressed 3
PRSS2 protease, serine, 2 (trypsin 2)
RHOBTB3 Rho-related BTB domain containing 3
SFN stratifin
SPINK1 serine peptidase inhibitor, Kazal type 1
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFPI2 tissue factor pathway inhibitor 2
TUBB2A tubulin, beta 2A class IIa
WT1 Wilms tumor 1