BRD-A05565054_(2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)methanone_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A05565054_(2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)methanone_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALG8 ALG8, alpha-1,3-glucosyltransferase
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CP ceruloplasmin (ferroxidase)
CXCR4 chemokine (C-X-C motif) receptor 4
FABP7 fatty acid binding protein 7, brain
FGG fibrinogen gamma chain
FMOD fibromodulin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDO1 indoleamine 2,3-dioxygenase 1
KCTD14 potassium channel tetramerization domain containing 14
LEF1 lymphoid enhancer-binding factor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
NSG1 neuron specific gene family member 1
NT5E 5'-nucleotidase, ecto (CD73)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLCL2 phospholipase C-like 2
PTN pleiotrophin
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SATB2 SATB homeobox 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
TRDV3 T cell receptor delta variable 3
TSKU tsukushi, small leucine rich proteoglycan
WDR7 WD repeat domain 7

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADI1 acireductone dioxygenase 1
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
BST2 bone marrow stromal cell antigen 2
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
CPB1 carboxypeptidase B1 (tissue)
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
DCLK1 doublecortin-like kinase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELF1 E74-like factor 1 (ets domain transcription factor)
FGF13 fibroblast growth factor 13
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
NNMT nicotinamide N-methyltransferase
PROM1 prominin 1
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SRSF7 serine/arginine-rich splicing factor 7
STOM stomatin
STXBP2 syntaxin binding protein 2
TBX3 T-box 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
THBS1 thrombospondin 1
TMEM47 transmembrane protein 47
TPBG trophoblast glycoprotein
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5