BRD-A04756508_NORGESTIMATE_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A04756508_NORGESTIMATE_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD10 ankyrin repeat domain 10
ATP11B ATPase, class VI, type 11B
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
EXT1 exostosin glycosyltransferase 1
FBLN1 fibulin 1
FBN1 fibrillin 1
GBP1 guanylate binding protein 1, interferon-inducible
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HOMER3 homer scaffolding protein 3
HOXB6 homeobox B6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IL32 interleukin 32
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
JCHAIN joining chain of multimeric IgA and IgM
LIMCH1 LIM and calponin homology domains 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TMEM176B transmembrane protein 176B
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
WDR7 WD repeat domain 7
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
BEX1 brain expressed, X-linked 1
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HP haptoglobin
MARCKSL1 MARCKS-like 1
NFIB nuclear factor I/B
NUTF2 nuclear transport factor 2
PEG3 paternally expressed 3
RPA3 replication protein A3, 14kDa
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
SLIRP SRA stem-loop interacting RNA binding protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
TPPP3 tubulin polymerization-promoting protein family member 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon