BRD-A04706586_Dibutyryl-cAMP, sodium salt_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-A04706586_Dibutyryl-cAMP, sodium salt_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL4C ADP-ribosylation factor-like 4C
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
DSC3 desmocollin 3
EGFL6 EGF-like-domain, multiple 6
EZR ezrin
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
MAGEA4 melanoma antigen family A4
NIT1 nitrilase 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RGCC regulator of cell cycle
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TRDV3 T cell receptor delta variable 3
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BST2 bone marrow stromal cell antigen 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CXCL12 chemokine (C-X-C motif) ligand 12
DEPTOR DEP domain containing MTOR-interacting protein
GMDS GDP-mannose 4,6-dehydratase
LEPR leptin receptor
MCUR1 mitochondrial calcium uniporter regulator 1
PDLIM1 PDZ and LIM domain 1
PLAC8 placenta-specific 8
PRSS2 protease, serine, 2 (trypsin 2)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TNC tenascin C
TSPAN8 tetraspanin 8
ZCCHC24 zinc finger, CCHC domain containing 24