BRD-A04706586_Dibutyryl-cAMP, sodium salt_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-A04706586_Dibutyryl-cAMP, sodium salt_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C3AR1 complement component 3a receptor 1
CD47 CD47 molecule
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DACT1 dishevelled-binding antagonist of beta-catenin 1
DSP desmoplakin
EIF5A eukaryotic translation initiation factor 5A
EPCAM epithelial cell adhesion molecule
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXD1 forkhead box D1
FZD10 frizzled class receptor 10
HAS2 hyaluronan synthase 2
HBB hemoglobin, beta
HOXB2 homeobox B2
HOXB6 homeobox B6
KDM5D lysine (K)-specific demethylase 5D
LEF1 lymphoid enhancer-binding factor 1
LOX lysyl oxidase
LRRN3 leucine rich repeat neuronal 3
LTBP2 latent transforming growth factor beta binding protein 2
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
NELL2 NEL-like 2 (chicken)
NRCAM neuronal cell adhesion molecule
NREP neuronal regeneration related protein
PF4 platelet factor 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTX3 pentraxin 3, long
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SDC2 syndecan 2
SERINC5 serine incorporator 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SH2D1A SH2 domain containing 1A
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SUSD6 sushi domain containing 6
TARP TCR gamma alternate reading frame protein
TNC tenascin C
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRH thyrotropin-releasing hormone
TXNIP thioredoxin interacting protein
WNT5B wingless-type MMTV integration site family, member 5B

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
APOD apolipoprotein D
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
C3ORF14 chromosome 3 open reading frame 14
COL4A6 collagen, type IV, alpha 6
CREB1 cAMP responsive element binding protein 1
CRELD2 cysteine-rich with EGF-like domains 2
CRIP1 cysteine-rich protein 1 (intestinal)
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DSG2 desmoglein 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF5 eukaryotic translation initiation factor 5
FAIM Fas apoptotic inhibitory molecule
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GATA6 GATA binding protein 6
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHM immunoglobulin heavy constant mu
KIAA1033 KIAA1033
LGALS1 lectin, galactoside-binding, soluble, 1
LY96 lymphocyte antigen 96
METTL3 methyltransferase like 3
NCK1 NCK adaptor protein 1
ORC1 origin recognition complex, subunit 1
PDGFD platelet derived growth factor D
PELI1 pellino E3 ubiquitin protein ligase 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLN phospholamban
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTK2 protein tyrosine kinase 2
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGCC regulator of cell cycle
RTN2 reticulon 2
SAMD4A sterile alpha motif domain containing 4A
SIK1 salt-inducible kinase 1
SIVA1 SIVA1, apoptosis-inducing factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPRED2 sprouty-related, EVH1 domain containing 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM5 transmembrane protein 5
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TTN titin
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TXNDC9 thioredoxin domain containing 9
TXNL4B thioredoxin-like 4B
YBX3 Y box binding protein 3
ZDHHC11 zinc finger, DHHC-type containing 11