BRD-A04553218_DEXCHLORPHENIRAMINE MALEATE_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

14 genes differentially expressed following the BRD-A04553218_DEXCHLORPHENIRAMINE MALEATE_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AMIGO2 adhesion molecule with Ig-like domain 2
AUTS2 autism susceptibility candidate 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR3 fibroblast growth factor receptor 3
MAN1A1 mannosidase, alpha, class 1A, member 1
SNAI2 snail family zinc finger 2

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CXCL8 chemokine (C-X-C motif) ligand 8
FAM134B family with sequence similarity 134, member B
LTBP3 latent transforming growth factor beta binding protein 3
LXN latexin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)