BRD-A04308630_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-A04308630_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
APOB apolipoprotein B
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC14B cell division cycle 14B
CLDND1 claudin domain containing 1
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
HBE1 hemoglobin, epsilon 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI30 interferon, gamma-inducible protein 30
IFNGR1 interferon gamma receptor 1
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB31 RAB31, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
SGK1 serum/glucocorticoid regulated kinase 1
SYNGR3 synaptogyrin 3
TSPAN7 tetraspanin 7
UBE2A ubiquitin-conjugating enzyme E2A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
EIF5A eukaryotic translation initiation factor 5A
FKSG49 FKSG49
HOXC6 homeobox C6
MGP matrix Gla protein
MYH11 myosin, heavy chain 11, smooth muscle
NRN1 neuritin 1
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SRPX sushi-repeat containing protein, X-linked
ZNF160 zinc finger protein 160