BRD-A03359064_ICI-89406_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-A03359064_ICI-89406_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ARMCX2 armadillo repeat containing, X-linked 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CD40 CD40 molecule, TNF receptor superfamily member 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FKBP4 FK506 binding protein 4, 59kDa
H2AFV H2A histone family, member V
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI16 interferon, gamma-inducible protein 16
IGL immunoglobulin lambda locus
IPO13 importin 13
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LOC100505650 uncharacterized LOC100505650
MAOA monoamine oxidase A
MMP9 matrix metallopeptidase 9
MX1 MX dynamin-like GTPase 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
RGCC regulator of cell cycle
RPS5 ribosomal protein S5
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
SH3YL1 SH3 and SYLF domain containing 1
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB3 tribbles pseudokinase 3
XIST X inactive specific transcript (non-protein coding)
ZBED5 zinc finger, BED-type containing 5

decreased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AK4 adenylate kinase 4
ASPN asporin
BAG2 BCL2-associated athanogene 2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
COCH cochlin
COL14A1 collagen, type XIV, alpha 1
COL1A1 collagen, type I, alpha 1
COMP cartilage oligomeric matrix protein
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DACT1 dishevelled-binding antagonist of beta-catenin 1
F13A1 coagulation factor XIII, A1 polypeptide
FAR2 fatty acyl CoA reductase 2
FBN1 fibrillin 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FOXD1 forkhead box D1
FSCN1 fascin actin-bundling protein 1
GMDS GDP-mannose 4,6-dehydratase
GPC3 glypican 3
GPM6B glycoprotein M6B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IL17RB interleukin 17 receptor B
LMNA lamin A/C
MAN1A1 mannosidase, alpha, class 1A, member 1
MFAP5 microfibrillar associated protein 5
MYO5C myosin VC
NR2F1 nuclear receptor subfamily 2, group F, member 1
OLFML2B olfactomedin-like 2B
PDLIM1 PDZ and LIM domain 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGAM1 phosphoglycerate mutase 1 (brain)
PMP22 peripheral myelin protein 22
PON2 paraoxonase 2
PRPS2 phosphoribosyl pyrophosphate synthetase 2
RGS2 regulator of G-protein signaling 2
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SEPT11 septin 11
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SSFA2 sperm specific antigen 2
STK26 serine/threonine protein kinase 26
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
TOX3 TOX high mobility group box family member 3
TWIST1 twist family bHLH transcription factor 1
TYRP1 tyrosinase-related protein 1
ZEB2 zinc finger E-box binding homeobox 2