BRD-A03216249_mepivacaine_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-A03216249_mepivacaine_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ADIRF adipogenesis regulatory factor
ADK adenosine kinase
AKR1C3 aldo-keto reductase family 1, member C3
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
COL14A1 collagen, type XIV, alpha 1
CSRP1 cysteine and glycine-rich protein 1
FHL1 four and a half LIM domains 1
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
KRT19 keratin 19, type I
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NDRG2 NDRG family member 2
PCOLCE procollagen C-endopeptidase enhancer
PDGFRL platelet-derived growth factor receptor-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRELP proline/arginine-rich end leucine-rich repeat protein
SDC4 syndecan 4
SORBS3 sorbin and SH3 domain containing 3
TSPAN3 tetraspanin 3
TSPAN4 tetraspanin 4
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A5 collagen, type IV, alpha 5
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
TRIB2 tribbles pseudokinase 2