BRD-A02333338_C3393M50_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

154 genes differentially expressed following the BRD-A02333338_C3393M50_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
AEBP1 AE binding protein 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
ASPN asporin
ATF3 activating transcription factor 3
CADM1 cell adhesion molecule 1
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHN1 chimerin 1
CKB creatine kinase, brain
CLDN3 claudin 3
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COPA coatomer protein complex, subunit alpha
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
ECM1 extracellular matrix protein 1
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ENO1 enolase 1, (alpha)
FABP7 fatty acid binding protein 7, brain
FKBP1A FK506 binding protein 1A, 12kDa
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
GAGE3 G antigen 3
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
GREB1 growth regulation by estrogen in breast cancer 1
HIST1H2BD histone cluster 1, H2bd
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ISYNA1 inositol-3-phosphate synthase 1
KRT19 keratin 19, type I
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
LRRC15 leucine rich repeat containing 15
LRRC41 leucine rich repeat containing 41
LUM lumican
MAOA monoamine oxidase A
MCL1 myeloid cell leukemia 1
MMP11 matrix metallopeptidase 11
MMP9 matrix metallopeptidase 9
ORC1 origin recognition complex, subunit 1
PICALM phosphatidylinositol binding clathrin assembly protein
PRAME preferentially expressed antigen in melanoma
PRPF6 pre-mRNA processing factor 6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SNAI2 snail family zinc finger 2
SST somatostatin
STIP1 stress-induced phosphoprotein 1
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKT transketolase
TMEM259 transmembrane protein 259
TMSB15A thymosin beta 15a
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACTG2 actin, gamma 2, smooth muscle, enteric
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
BCL3 B-cell CLL/lymphoma 3
BCL7B B-cell CLL/lymphoma 7B
C2CD5 C2 calcium-dependent domain containing 5
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CCNF cyclin F
CDC25A cell division cycle 25A
CDK17 cyclin-dependent kinase 17
CDK7 cyclin-dependent kinase 7
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNN1 calponin 1, basic, smooth muscle
CSRP1 cysteine and glycine-rich protein 1
CTPS1 CTP synthase 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL2 chemokine (C-X-C motif) ligand 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ETV5 ets variant 5
FCGBP Fc fragment of IgG binding protein
GCH1 GTP cyclohydrolase 1
GPX2 glutathione peroxidase 2
GRWD1 glutamate-rich WD repeat containing 1
HOXA5 homeobox A5
HSPH1 heat shock 105kDa/110kDa protein 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JADE2 jade family PHD finger 2
JMJD6 jumonji domain containing 6
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD12 potassium channel tetramerization domain containing 12
KIF2C kinesin family member 2C
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
MTF2 metal response element binding transcription factor 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
PDGFA platelet-derived growth factor alpha polypeptide
PDHX pyruvate dehydrogenase complex, component X
PDS5B PDS5 cohesin associated factor B
PLK2 polo-like kinase 2
PLS1 plastin 1
PNN pinin, desmosome associated protein
PNP purine nucleoside phosphorylase
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PSPC1 paraspeckle component 1
RAE1 ribonucleic acid export 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS2 regulator of G-protein signaling 2
RPP38 ribonuclease P/MRP 38kDa subunit
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNX11 sorting nexin 11
SPRR1A small proline-rich protein 1A
SRGN serglycin
STOM stomatin
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNM synemin, intermediate filament protein
TACC2 transforming, acidic coiled-coil containing protein 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THAP11 THAP domain containing 11
TNPO1 transportin 1
TUBA4A tubulin, alpha 4a
TXLNA taxilin alpha
USP1 ubiquitin specific peptidase 1
ZMYM2 zinc finger, MYM-type 2