BRD-A02180903_BETAMETHASONE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-A02180903_BETAMETHASONE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA6 annexin A6
CA2 carbonic anhydrase II
CD47 CD47 molecule
CDC42 cell division cycle 42
CLGN calmegin
DDIT4 DNA-damage-inducible transcript 4
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLRX glutaredoxin (thioltransferase)
HSPA2 heat shock 70kDa protein 2
KIAA1324 KIAA1324
KLK11 kallikrein-related peptidase 11
LAMA3 laminin, alpha 3
LTF lactotransferrin
MACF1 microtubule-actin crosslinking factor 1
MAPK6 mitogen-activated protein kinase 6
MYBPC1 myosin binding protein C, slow type
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PALLD palladin, cytoskeletal associated protein
PGC progastricsin (pepsinogen C)
SFN stratifin
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
CCDC85B coiled-coil domain containing 85B
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CTSC cathepsin C
EMX2 empty spiracles homeobox 2
F13A1 coagulation factor XIII, A1 polypeptide
FRY furry homolog (Drosophila)
IGFBP3 insulin-like growth factor binding protein 3
LEF1 lymphoid enhancer-binding factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
OSBPL10 oxysterol binding protein-like 10
PLS3 plastin 3
PON2 paraoxonase 2
RAI14 retinoic acid induced 14