BRD-A02180903_BETAMETHASONE_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the BRD-A02180903_BETAMETHASONE_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AHNAK AHNAK nucleoprotein
AQP9 aquaporin 9
AREG amphiregulin
ASS1 argininosuccinate synthase 1
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFD complement factor D (adipsin)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CP ceruloplasmin (ferroxidase)
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CRIP2 cysteine-rich protein 2
CSTA cystatin A (stefin A)
CYB561 cytochrome b561
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
F13A1 coagulation factor XIII, A1 polypeptide
FKBP5 FK506 binding protein 5
FNDC3B fibronectin type III domain containing 3B
FOXO3 forkhead box O3
FSTL3 follistatin-like 3 (secreted glycoprotein)
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GREB1 growth regulation by estrogen in breast cancer 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
KLF9 Kruppel-like factor 9
KRT14 keratin 14, type I
MAOA monoamine oxidase A
MCL1 myeloid cell leukemia 1
MME membrane metallo-endopeptidase
MSMB microseminoprotein, beta-
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NCOA4 nuclear receptor coactivator 4
NDRG1 N-myc downstream regulated 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM1 PDZ and LIM domain 1
PER1 period circadian clock 1
PKP2 plakophilin 2
PRKCD protein kinase C, delta
PTHLH parathyroid hormone-like hormone
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIDT2 SID1 transmembrane family, member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SNX11 sorting nexin 11
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SQRDL sulfide quinone reductase-like (yeast)
STOM stomatin
SYBU syntabulin (syntaxin-interacting)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNS1 tensin 1
TRAPPC6A trafficking protein particle complex 6A
TREM1 triggering receptor expressed on myeloid cells 1
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TSPAN31 tetraspanin 31
TXNIP thioredoxin interacting protein
VAMP8 vesicle-associated membrane protein 8
VNN1 vanin 1
WISP2 WNT1 inducible signaling pathway protein 2
YPEL5 yippee-like 5 (Drosophila)
ZBTB16 zinc finger and BTB domain containing 16
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BAMBI BMP and activin membrane-bound inhibitor
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BRCA1 breast cancer 1, early onset
BTG3 BTG family, member 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDCA4 cell division cycle associated 4
CENPA centromere protein A
CENPU centromere protein U
CLU clusterin
CNN3 calponin 3, acidic
COLEC12 collectin sub-family member 12
CPB1 carboxypeptidase B1 (tissue)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DONSON downstream neighbor of SON
DST dystonin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ESR1 estrogen receptor 1
ETV1 ets variant 1
EXO1 exonuclease 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM129A family with sequence similarity 129, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GREM1 gremlin 1, DAN family BMP antagonist
GTSE1 G-2 and S-phase expressed 1
HAT1 histone acetyltransferase 1
HJURP Holliday junction recognition protein
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
JCHAIN joining chain of multimeric IgA and IgM
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
LAPTM4B lysosomal protein transmembrane 4 beta
LIF leukemia inhibitory factor
LIG1 ligase I, DNA, ATP-dependent
MACF1 microtubule-actin crosslinking factor 1
MCM10 minichromosome maintenance complex component 10
MCM5 minichromosome maintenance complex component 5
MELK maternal embryonic leucine zipper kinase
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAPH non-SMC condensin I complex, subunit H
NPAS2 neuronal PAS domain protein 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
PBK PDZ binding kinase
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PMP22 peripheral myelin protein 22
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POU2AF1 POU class 2 associating factor 1
PPIF peptidylprolyl isomerase F
PRC1 protein regulator of cytokinesis 1
PRRX1 paired related homeobox 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
RFC2 replication factor C (activator 1) 2, 40kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RRM2 ribonucleotide reductase M2
SACS sacsin molecular chaperone
SEPT10 septin 10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC4 structural maintenance of chromosomes 4
SOX9 SRY (sex determining region Y)-box 9
SPAG5 sperm associated antigen 5
SPC25 SPC25, NDC80 kinetochore complex component
SPRY2 sprouty homolog 2 (Drosophila)
SYNJ2 synaptojanin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM47 transmembrane protein 47
TOP2A topoisomerase (DNA) II alpha 170kDa
TPBG trophoblast glycoprotein
TSPAN7 tetraspanin 7
VGLL4 vestigial-like family member 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZIC1 Zic family member 1