BRD-A02176148_TUBAIC ACID_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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34 genes differentially expressed following the BRD-A02176148_TUBAIC ACID_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAST calpastatin
CD52 CD52 molecule
CLC Charcot-Leyden crystal galectin
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
FN1 fibronectin 1
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
GULP1 GULP, engulfment adaptor PTB domain containing 1
IDO1 indoleamine 2,3-dioxygenase 1
LPAR6 lysophosphatidic acid receptor 6
LUM lumican
MEG3 maternally expressed 3 (non-protein coding)
MKNK1 MAP kinase interacting serine/threonine kinase 1
MOSPD1 motile sperm domain containing 1
MSN moesin
MUC16 mucin 16, cell surface associated
PAEP progestagen-associated endometrial protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
SPON1 spondin 1, extracellular matrix protein

decreased expression

Symbol Name
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FERMT2 fermitin family member 2
HK2 hexokinase 2
NRN1 neuritin 1
PTGES prostaglandin E synthase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THAP11 THAP domain containing 11
UGCG UDP-glucose ceramide glucosyltransferase