BRD-A01960364_PD 00735_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A01960364_PD 00735_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACVR1B activin A receptor, type IB
ARG2 arginase 2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD93 CD93 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLDN8 claudin 8
CST1 cystatin SN
DPYSL3 dihydropyrimidinase-like 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPCAM epithelial cell adhesion molecule
FSD1 fibronectin type III and SPRY domain containing 1
GATA3 GATA binding protein 3
GNAS GNAS complex locus
HHEX hematopoietically expressed homeobox
KRT18 keratin 18, type I
MAGEA3 melanoma antigen family A3
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
NELL2 NEL-like 2 (chicken)
PCBP2 poly(rC) binding protein 2
PERP PERP, TP53 apoptosis effector
PODXL podocalyxin-like
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SOCS2 suppressor of cytokine signaling 2
SPARCL1 SPARC-like 1 (hevin)
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTN1 actinin, alpha 1
AKR1C1 aldo-keto reductase family 1, member C1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CSRP1 cysteine and glycine-rich protein 1
CTSK cathepsin K
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DICER1 dicer 1, ribonuclease type III
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0125 KIAA0125
MAGED1 melanoma antigen family D1
MMD monocyte to macrophage differentiation-associated
MMP7 matrix metallopeptidase 7
MPZL1 myelin protein zero-like 1
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PTGES prostaglandin E synthase
RABGAP1L RAB GTPase activating protein 1-like
SPRY2 sprouty homolog 2 (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
UGCG UDP-glucose ceramide glucosyltransferase
VCAM1 vascular cell adhesion molecule 1
YME1L1 YME1-like 1 ATPase