BRD-A01645196_garcinol_PC3_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-A01645196_garcinol_PC3_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ADGRG6 adhesion G protein-coupled receptor G6
AGR2 anterior gradient 2
ANGPT1 angiopoietin 1
ANXA3 annexin A3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CBS cystathionine-beta-synthase
CDA cytidine deaminase
CDC42 cell division cycle 42
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
COL9A2 collagen, type IX, alpha 2
CXCL13 chemokine (C-X-C motif) ligand 13
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FOLR1 folate receptor 1 (adult)
GOLIM4 golgi integral membrane protein 4
GREM1 gremlin 1, DAN family BMP antagonist
GRN granulin
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
IRS2 insulin receptor substrate 2
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LINC00341 long intergenic non-protein coding RNA 341
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MB myoglobin
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYBPC1 myosin binding protein C, slow type
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PHGDH phosphoglycerate dehydrogenase
PON3 paraoxonase 3
PRR16 proline rich 16
RPS11 ribosomal protein S11
SARS seryl-tRNA synthetase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF1 splicing factor 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPRY2 sprouty homolog 2 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM47 transmembrane protein 47
TTN titin
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C3 complement component 3
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN10 claudin 10
CPA3 carboxypeptidase A3 (mast cell)
CPB1 carboxypeptidase B1 (tissue)
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EFHD1 EF-hand domain family, member D1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGFR3 fibroblast growth factor receptor 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GJA1 gap junction protein, alpha 1, 43kDa
HBB hemoglobin, beta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXB2 homeobox B2
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
LAMP5 lysosomal-associated membrane protein family, member 5
LRRC17 leucine rich repeat containing 17
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
OLFM1 olfactomedin 1
PDLIM1 PDZ and LIM domain 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
REEP1 receptor accessory protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SNAP25 synaptosomal-associated protein, 25kDa
SPAG4 sperm associated antigen 4
SRGN serglycin
TACSTD2 tumor-associated calcium signal transducer 2
THAP11 THAP domain containing 11
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)