BRD-A01645196_garcinol_MCF7_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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55 genes differentially expressed following the BRD-A01645196_garcinol_MCF7_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD2 abhydrolase domain containing 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
CTSE cathepsin E
DDIT4 DNA-damage-inducible transcript 4
FRZB frizzled-related protein
FXYD5 FXYD domain containing ion transport regulator 5
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOXB2 homeobox B2
MSMB microseminoprotein, beta-
PHGDH phosphoglycerate dehydrogenase
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
SCRG1 stimulator of chondrogenesis 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC35F2 solute carrier family 35, member F2
SORD sorbitol dehydrogenase
TARP TCR gamma alternate reading frame protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPBG trophoblast glycoprotein
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRL2 adhesion G protein-coupled receptor L2
ARHGAP29 Rho GTPase activating protein 29
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLDN8 claudin 8
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
DEFB1 defensin, beta 1
EFNB2 ephrin-B2
EREG epiregulin
FBXL12 F-box and leucine-rich repeat protein 12
GATA6 GATA binding protein 6
HACD1 3-hydroxyacyl-CoA dehydratase 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT23 keratin 23, type I
LOXL2 lysyl oxidase-like 2
NRP1 neuropilin 1
ODC1 ornithine decarboxylase 1
PEG10 paternally expressed 10
PODXL podocalyxin-like
PRAME preferentially expressed antigen in melanoma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RGS13 regulator of G-protein signaling 13
S100A8 S100 calcium binding protein A8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SRGN serglycin
TMPRSS3 transmembrane protease, serine 3
TNC tenascin C
TOX3 TOX high mobility group box family member 3