BRD-A01645196_garcinol_HA1E_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A01645196_garcinol_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD200 CD200 molecule
CYBRD1 cytochrome b reductase 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ISCU iron-sulfur cluster assembly enzyme
LYPLA1 lysophospholipase I
MAOA monoamine oxidase A
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLAT plasminogen activator, tissue
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA9 carbonic anhydrase IX
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CELF2 CUGBP, Elav-like family member 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
CRYAB crystallin, alpha B
CST3 cystatin C
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FABP7 fatty acid binding protein 7, brain
FMOD fibromodulin
FST follistatin
GOLGA8A golgin A8 family, member A
GPC3 glypican 3
GPX3 glutathione peroxidase 3
GSTT1 glutathione S-transferase theta 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGFBP6 insulin-like growth factor binding protein 6
IL1R2 interleukin 1 receptor, type II
IL32 interleukin 32
MMP2 matrix metallopeptidase 2
NDRG1 N-myc downstream regulated 1
NRCAM neuronal cell adhesion molecule
PLTP phospholipid transfer protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPAG4 sperm associated antigen 4
TMEM176B transmembrane protein 176B
TNNC1 troponin C type 1 (slow)
TXNIP thioredoxin interacting protein
ZFP36L2 ZFP36 ring finger protein-like 2