BRD-A01643550_PREDNISOLONE ACETATE_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

131 genes differentially expressed following the BRD-A01643550_PREDNISOLONE ACETATE_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP13 A kinase (PRKA) anchor protein 13
ASS1 argininosuccinate synthase 1
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
CA1 carbonic anhydrase I
CD24 CD24 molecule
CD9 CD9 molecule
CFD complement factor D (adipsin)
CLDN7 claudin 7
CLDN8 claudin 8
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
EFNA1 ephrin-A1
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FKBP5 FK506 binding protein 5
GAL galanin/GMAP prepropeptide
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
JUP junction plakoglobin
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCTD5 potassium channel tetramerization domain containing 5
KLF9 Kruppel-like factor 9
LTF lactotransferrin
LUM lumican
MAOA monoamine oxidase A
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MME membrane metallo-endopeptidase
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1B myosin IB
NAMPT nicotinamide phosphoribosyltransferase
PER1 period circadian clock 1
PIP prolactin-induced protein
PPL periplakin
PRR15L proline rich 15-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A8 S100 calcium binding protein A8
SLPI secretory leukocyte peptidase inhibitor
SOD2 superoxide dismutase 2, mitochondrial
TACSTD2 tumor-associated calcium signal transducer 2
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARL4C ADP-ribosylation factor-like 4C
AXL AXL receptor tyrosine kinase
BAMBI BMP and activin membrane-bound inhibitor
BGN biglycan
CDC25B cell division cycle 25B
CDC45 cell division cycle 45
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL4A2 collagen, type IV, alpha 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLX2 distal-less homeobox 2
DUSP4 dual specificity phosphatase 4
EMP3 epithelial membrane protein 3
ETV5 ets variant 5
FADS1 fatty acid desaturase 1
FHL2 four and a half LIM domains 2
FLRT2 fibronectin leucine rich transmembrane protein 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
H1F0 H1 histone family, member 0
IER3 immediate early response 3
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
MDK midkine (neurite growth-promoting factor 2)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDP Norrie disease (pseudoglioma)
NPY neuropeptide Y
NTS neurotensin
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAT ornithine aminotransferase
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PEG10 paternally expressed 10
PRSS2 protease, serine, 2 (trypsin 2)
PTN pleiotrophin
RBP1 retinol binding protein 1, cellular
RECQL RecQ helicase-like
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL37A ribosomal protein L37a
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SOBP sine oculis binding protein homolog (Drosophila)
SPDEF SAM pointed domain containing ETS transcription factor
SPRY2 sprouty homolog 2 (Drosophila)
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
TYMS thymidylate synthetase
WBP5 WW domain binding protein 5
WSB2 WD repeat and SOCS box containing 2
XIST X inactive specific transcript (non-protein coding)