BRD-A01643550_PREDNISOLONE ACETATE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-A01643550_PREDNISOLONE ACETATE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCHE butyrylcholinesterase
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
CCL5 chemokine (C-C motif) ligand 5
CD38 CD38 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKB creatine kinase, brain
COL11A1 collagen, type XI, alpha 1
CXCL9 chemokine (C-X-C motif) ligand 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DICER1 dicer 1, ribonuclease type III
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
ESR1 estrogen receptor 1
FABP4 fatty acid binding protein 4, adipocyte
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GCLC glutamate-cysteine ligase, catalytic subunit
GPNMB glycoprotein (transmembrane) nmb
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IL7R interleukin 7 receptor
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KDM5D lysine (K)-specific demethylase 5D
KIAA0485 uncharacterized LOC57235
KLF9 Kruppel-like factor 9
KRAS Kirsten rat sarcoma viral oncogene homolog
MAP2K3 mitogen-activated protein kinase kinase 3
MT1X metallothionein 1X
MXRA5 matrix-remodelling associated 5
PAWR PRKC, apoptosis, WT1, regulator
PCP4 Purkinje cell protein 4
PRNP prion protein
RGS1 regulator of G-protein signaling 1
RNF130 ring finger protein 130
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SELENBP1 selenium binding protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRRM2 serine/arginine repetitive matrix 2
SULF1 sulfatase 1
TCEAL4 transcription elongation factor A (SII)-like 4
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADD3 adducin 3 (gamma)
ADGRG1 adhesion G protein-coupled receptor G1
AKAP12 A kinase (PRKA) anchor protein 12
ANK2 ankyrin 2, neuronal
ASCL1 achaete-scute family bHLH transcription factor 1
BST2 bone marrow stromal cell antigen 2
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
DCLK1 doublecortin-like kinase 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGR3 early growth response 3
EIF3G eukaryotic translation initiation factor 3, subunit G
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FOXC1 forkhead box C1
GPC3 glypican 3
GREB1 growth regulation by estrogen in breast cancer 1
GRK5 G protein-coupled receptor kinase 5
HOXB2 homeobox B2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
KRT23 keratin 23, type I
LIMA1 LIM domain and actin binding 1
LPAR1 lysophosphatidic acid receptor 1
MPO myeloperoxidase
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
PBX3 pre-B-cell leukemia homeobox 3
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDZK1 PDZ domain containing 1
POPDC3 popeye domain containing 3
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A7 S100 calcium binding protein A7
SEPP1 selenoprotein P, plasma, 1
SPTBN1 spectrin, beta, non-erythrocytic 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMPRSS4 transmembrane protease, serine 4
TNC tenascin C
VWA5A von Willebrand factor A domain containing 5A
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon