BRD-A01593789_CHLORMADINONE ACETATE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-A01593789_CHLORMADINONE ACETATE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACSL3 acyl-CoA synthetase long-chain family member 3
AGR2 anterior gradient 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARMCX3 armadillo repeat containing, X-linked 3
BBX bobby sox homolog (Drosophila)
CADPS2 Ca++-dependent secretion activator 2
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFB complement factor B
CHPT1 choline phosphotransferase 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DICER1 dicer 1, ribonuclease type III
DLG5 discs, large homolog 5 (Drosophila)
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EMP3 epithelial membrane protein 3
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
GPER1 G protein-coupled estrogen receptor 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOMER2 homer scaffolding protein 2
IL6ST interleukin 6 signal transducer
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
KDM4B lysine (K)-specific demethylase 4B
KIAA1324 KIAA1324
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LGMN legumain
MAGED1 melanoma antigen family D1
MALT1 MALT1 paracaspase
MKNK2 MAP kinase interacting serine/threonine kinase 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
PGC progastricsin (pepsinogen C)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRSS8 protease, serine, 8
PSD3 pleckstrin and Sec7 domain containing 3
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFN stratifin
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC44A4 solute carrier family 44, member 4
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOX9 SRY (sex determining region Y)-box 9
STK39 serine threonine kinase 39
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMC5 transmembrane channel-like 5
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRE5 adhesion G protein-coupled receptor E5
AHNAK2 AHNAK nucleoprotein 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CCDC85B coiled-coil domain containing 85B
CD200 CD200 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CX3CR1 chemokine (C-X3-C motif) receptor 1
HOPX HOP homeobox
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
JAG1 jagged 1
LGALS4 lectin, galactoside-binding, soluble, 4
MCAM melanoma cell adhesion molecule
MRPL15 mitochondrial ribosomal protein L15
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NOP56 NOP56 ribonucleoprotein
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLS3 plastin 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRR7 proline rich 7 (synaptic)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGCC regulator of cell cycle
RSL1D1 ribosomal L1 domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIB1 tribbles pseudokinase 1
TYRP1 tyrosinase-related protein 1