BRD-A01346607_FLUMETHASONE_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-A01346607_FLUMETHASONE_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
C10ORF10 chromosome 10 open reading frame 10
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CES1 carboxylesterase 1
CPM carboxypeptidase M
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
DHRS1 dehydrogenase/reductase (SDR family) member 1
DSP desmoplakin
F5 coagulation factor V (proaccelerin, labile factor)
FGG fibrinogen gamma chain
FKBP5 FK506 binding protein 5
FOXO3 forkhead box O3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
IFI27 interferon, alpha-inducible protein 27
KLF9 Kruppel-like factor 9
KRT14 keratin 14, type I
LPIN1 lipin 1
MAOA monoamine oxidase A
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORM1 orosomucoid 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM1 PDZ and LIM domain 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRSS8 protease, serine, 8
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STK39 serine threonine kinase 39
TNS1 tensin 1
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TXNIP thioredoxin interacting protein
VNN1 vanin 1
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
BAMBI BMP and activin membrane-bound inhibitor
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
C6ORF62 chromosome 6 open reading frame 62
CCL2 chemokine (C-C motif) ligand 2
CDC25A cell division cycle 25A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPU centromere protein U
CLIC4 chloride intracellular channel 4
CNN3 calponin 3, acidic
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
DCK deoxycytidine kinase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DLD dihydrolipoamide dehydrogenase
DUSP4 dual specificity phosphatase 4
EIF5 eukaryotic translation initiation factor 5
EMX2 empty spiracles homeobox 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
FSTL1 follistatin-like 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
GRIA2 glutamate receptor, ionotropic, AMPA 2
HAT1 histone acetyltransferase 1
HES1 hes family bHLH transcription factor 1
HIST1H4C histone cluster 1, H4c
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
KLHL9 kelch-like family member 9
LIG1 ligase I, DNA, ATP-dependent
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR1 lysophosphatidic acid receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MCM5 minichromosome maintenance complex component 5
MID1 midline 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP10 matrix metallopeptidase 10
NEBL nebulette
NTS neurotensin
NUSAP1 nucleolar and spindle associated protein 1
PCNA proliferating cell nuclear antigen
PDE4B phosphodiesterase 4B, cAMP-specific
PLK2 polo-like kinase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRC1 protein regulator of cytokinesis 1
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
RND3 Rho family GTPase 3
RRM2 ribonucleotide reductase M2
RTN2 reticulon 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD1 SMAD family member 1
SOX9 SRY (sex determining region Y)-box 9
SPON1 spondin 1, extracellular matrix protein
SPRY2 sprouty homolog 2 (Drosophila)
TEX10 testis expressed 10
TMEM158 transmembrane protein 158 (gene/pseudogene)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon