BRD-A01317026_81882_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-A01317026_81882_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ALDOB aldolase B, fructose-bisphosphate
AREG amphiregulin
ASPN asporin
C10ORF10 chromosome 10 open reading frame 10
CALD1 caldesmon 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CD52 CD52 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CFD complement factor D (adipsin)
CLC Charcot-Leyden crystal galectin
CLEC2B C-type lectin domain family 2, member B
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRELD2 cysteine-rich with EGF-like domains 2
CTSK cathepsin K
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DSP desmoplakin
ECM1 extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
FABP1 fatty acid binding protein 1, liver
FAM198B family with sequence similarity 198, member B
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
GAGE3 G antigen 3
HDAC9 histone deacetylase 9
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB2 homeobox B2
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IPO13 importin 13
IRF6 interferon regulatory factor 6
KLF9 Kruppel-like factor 9
LMO3 LIM domain only 3 (rhombotin-like 2)
MXRA5 matrix-remodelling associated 5
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NT5E 5'-nucleotidase, ecto (CD73)
PLAT plasminogen activator, tissue
PLXNB2 plexin B2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS16 regulator of G-protein signaling 16
SEPP1 selenoprotein P, plasma, 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
SULF1 sulfatase 1
TBXA2R thromboxane A2 receptor
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATG3 autophagy related 3
C8ORF4 chromosome 8 open reading frame 4
CCNA2 cyclin A2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CHSY1 chondroitin sulfate synthase 1
CNOT7 CCR4-NOT transcription complex, subunit 7
COL4A2 collagen, type IV, alpha 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DLK1 delta-like 1 homolog (Drosophila)
ERP29 endoplasmic reticulum protein 29
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HMOX1 heme oxygenase 1
HN1 hematological and neurological expressed 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KRT10 keratin 10, type I
MAGEA6 melanoma antigen family A6
MSH6 mutS homolog 6
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PBK PDZ binding kinase
PEBP1 phosphatidylethanolamine binding protein 1
PFKP phosphofructokinase, platelet
PHGDH phosphoglycerate dehydrogenase
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRMT1 protein arginine methyltransferase 1
PROM1 prominin 1
RPL39L ribosomal protein L39-like
S100A2 S100 calcium binding protein A2
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TPM1 tropomyosin 1 (alpha)
UBE2S ubiquitin-conjugating enzyme E2S