BRD-A00993607_ALPRENOLOL_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-A00993607_ALPRENOLOL_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AHR aryl hydrocarbon receptor
AMIGO2 adhesion molecule with Ig-like domain 2
ARL4C ADP-ribosylation factor-like 4C
ATP10D ATPase, class V, type 10D
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
COLEC12 collectin sub-family member 12
DENND1B DENN/MADD domain containing 1B
EMP1 epithelial membrane protein 1
EXT1 exostosin glycosyltransferase 1
FAM129A family with sequence similarity 129, member A
FZD6 frizzled class receptor 6
GLIPR1 GLI pathogenesis-related 1
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LPAR6 lysophosphatidic acid receptor 6
NT5E 5'-nucleotidase, ecto (CD73)
PLIN2 perilipin 2
PLXNA1 plexin A1
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
QPCT glutaminyl-peptide cyclotransferase
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SPON2 spondin 2, extracellular matrix protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
AGR2 anterior gradient 2
CCL19 chemokine (C-C motif) ligand 19
COMP cartilage oligomeric matrix protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL13 chemokine (C-X-C motif) ligand 13
FAM46A family with sequence similarity 46, member A
GOLGA8A golgin A8 family, member A
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
HPRT1 hypoxanthine phosphoribosyltransferase 1
MYO5C myosin VC
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLA2G16 phospholipase A2, group XVI
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6