BRD-A00420644_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A00420644_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ANKRD10 ankyrin repeat domain 10
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX1 brain expressed, X-linked 1
BTG1 B-cell translocation gene 1, anti-proliferative
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CST1 cystatin SN
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LDLR low density lipoprotein receptor
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHGDH phosphoglycerate dehydrogenase
PPARG peroxisome proliferator-activated receptor gamma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SLC16A4 solute carrier family 16, member 4
SOX4 SRY (sex determining region Y)-box 4
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TFF3 trefoil factor 3 (intestinal)
TM4SF4 transmembrane 4 L six family member 4
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADA adenosine deaminase
AK4 adenylate kinase 4
AMIGO2 adhesion molecule with Ig-like domain 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CRABP1 cellular retinoic acid binding protein 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DUSP2 dual specificity phosphatase 2
FRZB frizzled-related protein
GAL galanin/GMAP prepropeptide
GSTT1 glutathione S-transferase theta 1
ITGAV integrin, alpha V
IVNS1ABP influenza virus NS1A binding protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCNA proliferating cell nuclear antigen
TRIM14 tripartite motif containing 14
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)