BRD-A00420644_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

17 genes differentially expressed following the BRD-A00420644_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
DDIT4 DNA-damage-inducible transcript 4
PHGDH phosphoglycerate dehydrogenase
SFRP1 secreted frizzled-related protein 1
SQSTM1 sequestosome 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
CTSH cathepsin H
EIF5B eukaryotic translation initiation factor 5B
GTF3A general transcription factor IIIA
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KIF20A kinesin family member 20A
MMP1 matrix metallopeptidase 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB13 RAB13, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1