BRD-A00420644_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

111 genes differentially expressed following the BRD-A00420644_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP5 acid phosphatase 5, tartrate resistant
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLIC5 chloride intracellular channel 5
CTSB cathepsin B
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FGF13 fibroblast growth factor 13
FMO3 flavin containing monooxygenase 3
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GLIPR1 GLI pathogenesis-related 1
GPNMB glycoprotein (transmembrane) nmb
GPR137B G protein-coupled receptor 137B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
INHBA inhibin, beta A
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCOLN1 mucolipin 1
MGLL monoglyceride lipase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAU plasminogen activator, urokinase
RPS4Y1 ribosomal protein S4, Y-linked 1
SPRED2 sprouty-related, EVH1 domain containing 2
STK17A serine/threonine kinase 17a
TCTA T-cell leukemia translocation altered
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRBC1 T cell receptor beta constant 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
AHCYL1 adenosylhomocysteinase-like 1
CA12 carbonic anhydrase XII
CBX1 chromobox homolog 1
CD200 CD200 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNPY3 canopy FGF signaling regulator 3
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLK1 delta-like 1 homolog (Drosophila)
DPT dermatopontin
DPYD dihydropyrimidine dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FBP1 fructose-1,6-bisphosphatase 1
FCGBP Fc fragment of IgG binding protein
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GBP1 guanylate binding protein 1, interferon-inducible
GSTM3 glutathione S-transferase mu 3 (brain)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP4 insulin-like growth factor binding protein 4
IL1RN interleukin 1 receptor antagonist
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
KRT15 keratin 15, type I
LAMC1 laminin, gamma 1 (formerly LAMB2)
MANSC1 MANSC domain containing 1
MEIS2 Meis homeobox 2
MLPH melanophilin
MYBPC1 myosin binding protein C, slow type
MYOF myoferlin
NAV2 neuron navigator 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PADI2 peptidyl arginine deiminase, type II
PAM peptidylglycine alpha-amidating monooxygenase
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKCD protein kinase C, delta
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SNX7 sorting nexin 7
SPDEF SAM pointed domain containing ETS transcription factor
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TGFBR3 transforming growth factor, beta receptor III
TMC5 transmembrane channel-like 5
TTC39A tetratricopeptide repeat domain 39A
VNN1 vanin 1