BRD-A00420644_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-A00420644_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD10 ankyrin repeat domain 10
ANXA2P2 annexin A2 pseudogene 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID4B AT rich interactive domain 4B (RBP1-like)
ASNS asparagine synthetase (glutamine-hydrolyzing)
C3ORF52 chromosome 3 open reading frame 52
CAB39 calcium binding protein 39
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSTA cystatin A (stefin A)
CTSL cathepsin L
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EMP1 epithelial membrane protein 1
FASTKD5 FAST kinase domains 5
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
FXYD3 FXYD domain containing ion transport regulator 3
GABPB1 GA binding protein transcription factor, beta subunit 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTP1 glutathione S-transferase pi 1
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
IL6ST interleukin 6 signal transducer
INPP1 inositol polyphosphate-1-phosphatase
INSIG1 insulin induced gene 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
KLHL21 kelch-like family member 21
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LRRC15 leucine rich repeat containing 15
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPK6 mitogen-activated protein kinase 6
MCL1 myeloid cell leukemia 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIR22HG MIR22 host gene
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT2A metallothionein 2A
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OAT ornithine aminotransferase
PALLD palladin, cytoskeletal associated protein
PDLIM4 PDZ and LIM domain 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAUR plasminogen activator, urokinase receptor
PPARD peroxisome proliferator-activated receptor delta
PPIF peptidylprolyl isomerase F
RCAN1 regulator of calcineurin 1
RUFY3 RUN and FYVE domain containing 3
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SCGB2A2 secretoglobin, family 2A, member 2
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TES testin LIM domain protein
TUFT1 tuftelin 1
TXNRD1 thioredoxin reductase 1
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CD200 CD200 molecule
CLEC2B C-type lectin domain family 2, member B
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
GTF3A general transcription factor IIIA
GTSE1 G-2 and S-phase expressed 1
HMGN3 high mobility group nucleosomal binding domain 3
IFITM3 interferon induced transmembrane protein 3
NDC80 NDC80 kinetochore complex component
OBSL1 obscurin-like 1
PLK1 polo-like kinase 1
PSRC1 proline/serine-rich coiled-coil 1
PXDN peroxidasin
RAD21 RAD21 homolog (S. pombe)
SALL2 spalt-like transcription factor 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX11 SRY (sex determining region Y)-box 11
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
TBC1D31 TBC1 domain family, member 31
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNS3 tensin 3
TUBB2B tubulin, beta 2B class IIb
TYRP1 tyrosinase-related protein 1
ZIC1 Zic family member 1