BRD-A00420644_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A00420644_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARF4 ADP-ribosylation factor 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
EREG epiregulin
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAS Fas cell surface death receptor
FBXO11 F-box protein 11
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IL1R1 interleukin 1 receptor, type I
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
LIMA1 LIM domain and actin binding 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP1 matrix metallopeptidase 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RALB v-ral simian leukemia viral oncogene homolog B
RGCC regulator of cell cycle
RIPK2 receptor-interacting serine-threonine kinase 2
RNF167 ring finger protein 167
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHROOM2 shroom family member 2
STS steroid sulfatase (microsomal), isozyme S
STX1A syntaxin 1A (brain)
TRIM16 tripartite motif containing 16
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CCL19 chemokine (C-C motif) ligand 19
CFB complement factor B
CLU clusterin
COL2A1 collagen, type II, alpha 1
EFR3A EFR3 homolog A (S. cerevisiae)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGB fibrinogen beta chain
GPC3 glypican 3
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LDHB lactate dehydrogenase B
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MXRA7 matrix-remodelling associated 7
NUP210 nucleoporin 210kDa
PIP prolactin-induced protein
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
TNNT1 troponin T type 1 (skeletal, slow)
TUBA1A tubulin, alpha 1a