BRD-A00267231_HEMADO_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-A00267231_HEMADO_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD200 CD200 molecule
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CLMN calmin (calponin-like, transmembrane)
COCH cochlin
COG7 component of oligomeric golgi complex 7
COL4A5 collagen, type IV, alpha 5
CTNND1 catenin (cadherin-associated protein), delta 1
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
DEPTOR DEP domain containing MTOR-interacting protein
DHRS3 dehydrogenase/reductase (SDR family) member 3
DMXL2 Dmx-like 2
EFNB2 ephrin-B2
ELANE elastase, neutrophil expressed
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALC galactosylceramidase
GCLC glutamate-cysteine ligase, catalytic subunit
H2AFV H2A histone family, member V
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
INSM1 insulinoma-associated 1
IRF9 interferon regulatory factor 9
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LDOC1 leucine zipper, down-regulated in cancer 1
LPAR6 lysophosphatidic acid receptor 6
MEST mesoderm specific transcript
MMP9 matrix metallopeptidase 9
MT1F metallothionein 1F
MX1 MX dynamin-like GTPase 1
NELL2 NEL-like 2 (chicken)
NVL nuclear VCP-like
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLBD1 phospholipase B domain containing 1
PMM2 phosphomannomutase 2
PNMAL1 paraneoplastic Ma antigen family-like 1
PRAME preferentially expressed antigen in melanoma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRTN3 proteinase 3
PTPRF protein tyrosine phosphatase, receptor type, F
REEP1 receptor accessory protein 1
SFRP4 secreted frizzled-related protein 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPARCL1 SPARC-like 1 (hevin)
TARP TCR gamma alternate reading frame protein
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOP1 topoisomerase (DNA) I
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
ACOT9 acyl-CoA thioesterase 9
ADIRF adipogenesis regulatory factor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANXA5 annexin A5
ASCL1 achaete-scute family bHLH transcription factor 1
BAG2 BCL2-associated athanogene 2
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BDH2 3-hydroxybutyrate dehydrogenase, type 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC123 cell division cycle 123
COX7B cytochrome c oxidase subunit VIIb
CTSV cathepsin V
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
EGR3 early growth response 3
EPN2 epsin 2
FHL1 four and a half LIM domains 1
GPX3 glutathione peroxidase 3
HOMER1 homer scaffolding protein 1
HSPB8 heat shock 22kDa protein 8
IGHMBP2 immunoglobulin mu binding protein 2
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT7 keratin 7, type II
MET MET proto-oncogene, receptor tyrosine kinase
NEBL nebulette
PDIA6 protein disulfide isomerase family A, member 6
PID1 phosphotyrosine interaction domain containing 1
PLS3 plastin 3
PMEL premelanosome protein
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
RCAN1 regulator of calcineurin 1
RFC2 replication factor C (activator 1) 2, 40kDa
RHOB ras homolog family member B
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SFTPB surfactant protein B
SIK1 salt-inducible kinase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TM4SF1 transmembrane 4 L six family member 1
TSPAN8 tetraspanin 8
TXNDC9 thioredoxin domain containing 9
TYRP1 tyrosinase-related protein 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
VDAC1 voltage-dependent anion channel 1