BRD-A00267231_HEMADO_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-A00267231_HEMADO_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANGPT1 angiopoietin 1
ANXA4 annexin A4
ARL4C ADP-ribosylation factor-like 4C
ATF3 activating transcription factor 3
ATP11B ATPase, class VI, type 11B
BMP2 bone morphogenetic protein 2
CA2 carbonic anhydrase II
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD9 CD9 molecule
CHEK1 checkpoint kinase 1
CLCA1 chloride channel accessory 1
COL3A1 collagen, type III, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
CTNND1 catenin (cadherin-associated protein), delta 1
DENND1B DENN/MADD domain containing 1B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EVI2A ecotropic viral integration site 2A
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FGL2 fibrinogen-like 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FXYD3 FXYD domain containing ion transport regulator 3
GAGE3 G antigen 3
GATA6 GATA binding protein 6
IFI16 interferon, gamma-inducible protein 16
IGHM immunoglobulin heavy constant mu
IL13RA1 interleukin 13 receptor, alpha 1
IL1R1 interleukin 1 receptor, type I
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
LPAR6 lysophosphatidic acid receptor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MPZL2 myelin protein zero-like 2
NUSAP1 nucleolar and spindle associated protein 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCDH7 protocadherin 7
PLBD1 phospholipase B domain containing 1
PRKCI protein kinase C, iota
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SELENBP1 selenium binding protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SPTSSA serine palmitoyltransferase, small subunit A
SULF1 sulfatase 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRDV3 T cell receptor delta variable 3
TRIB1 tribbles pseudokinase 1
VNN1 vanin 1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARL4A ADP-ribosylation factor-like 4A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
C16ORF45 chromosome 16 open reading frame 45
C6ORF48 chromosome 6 open reading frame 48
CCDC92 coiled-coil domain containing 92
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLGN calmegin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOLR1 folate receptor 1 (adult)
HOXC6 homeobox C6
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JADE1 jade family PHD finger 1
KDM5D lysine (K)-specific demethylase 5D
KRT7 keratin 7, type II
MAP1B microtubule-associated protein 1B
MSX1 msh homeobox 1
NAP1L1 nucleosome assembly protein 1-like 1
NFIB nuclear factor I/B
NME4 NME/NM23 nucleoside diphosphate kinase 4
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARP2 poly (ADP-ribose) polymerase 2
PCDH9 protocadherin 9
PEBP1 phosphatidylethanolamine binding protein 1
PNKP polynucleotide kinase 3'-phosphatase
PRKCB protein kinase C, beta
PTGES prostaglandin E synthase
QDPR quinoid dihydropteridine reductase
RPL36 ribosomal protein L36
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMAD1 SMAD family member 1
SMS spermine synthase
STOM stomatin
STXBP2 syntaxin binding protein 2
TFF1 trefoil factor 1
TM4SF1 transmembrane 4 L six family member 1
WDTC1 WD and tetratricopeptide repeats 1