BRD-A00267231_HEMADO_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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64 genes differentially expressed following the BRD-A00267231_HEMADO_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRL2 adhesion G protein-coupled receptor L2
ARMCX1 armadillo repeat containing, X-linked 1
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCA4 chloride channel accessory 4
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYTIP cytohesin 1 interacting protein
DENND1B DENN/MADD domain containing 1B
DHRS2 dehydrogenase/reductase (SDR family) member 2
ERBB4 erb-b2 receptor tyrosine kinase 4
FHL1 four and a half LIM domains 1
HIC2 hypermethylated in cancer 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
KAZN kazrin, periplakin interacting protein
KRT5 keratin 5, type II
LPAR6 lysophosphatidic acid receptor 6
MEIS2 Meis homeobox 2
MPZL2 myelin protein zero-like 2
NEB nebulin
NPIPB3 nuclear pore complex interacting protein family, member B3
NXN nucleoredoxin
OSR2 odd-skipped related transciption factor 2
PCP4 Purkinje cell protein 4
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100A8 S100 calcium binding protein A8
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TPD52L1 tumor protein D52-like 1
TUSC3 tumor suppressor candidate 3

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA5 annexin A5
BIK BCL2-interacting killer (apoptosis-inducing)
C6ORF48 chromosome 6 open reading frame 48
CXCL8 chemokine (C-X-C motif) ligand 8
GADD45B growth arrest and DNA-damage-inducible, beta
GSTO1 glutathione S-transferase omega 1
IRS2 insulin receptor substrate 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
NPY neuropeptide Y
PDGFA platelet-derived growth factor alpha polypeptide
PMEPA1 prostate transmembrane protein, androgen induced 1
PRSS3 protease, serine, 3
RNF167 ring finger protein 167
SLCO1B3 solute carrier organic anion transporter family, member 1B3
STX1A syntaxin 1A (brain)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
TSPAN3 tetraspanin 3
VCAN versican
ZMYM2 zinc finger, MYM-type 2