B-cell chronic lymphocytic leukaemia-small lymphocytic lymphoma_Peripheral blood mononuclear cell_GSE8835 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE8835
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during B-cell chronic lymphocytic leukaemia-small lymphocytic lymphoma_Peripheral blood mononuclear cell_GSE8835 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
RPS15 ribosomal protein S15 3.36947
RPL13A ribosomal protein L13a 3.20746
RPL12 ribosomal protein L12 3.03644
CTCF CCCTC-binding factor (zinc finger protein) 2.81136
PHB2 prohibitin 2 2.76878
FBXW2 F-box and WD repeat domain containing 2 2.70339
AUP1 ancient ubiquitous protein 1 2.66881
MTDH metadherin 2.55268
KRT10 keratin 10, type I 2.53913
RPSA ribosomal protein SA 2.45288
NDRG3 NDRG family member 3 2.4395
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 2.41587
LYRM1 LYR motif containing 1 2.40402
FAM134C family with sequence similarity 134, member C 2.35018
RPL32 ribosomal protein L32 2.33899
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2.33835
HNRNPR heterogeneous nuclear ribonucleoprotein R 2.33423
TOR3A torsin family 3, member A 2.30623
RPS17 ribosomal protein S17 2.26636
AHCY adenosylhomocysteinase 2.25712
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.25462
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 2.23273
APOM apolipoprotein M 2.19327
HMGN2 high mobility group nucleosomal binding domain 2 2.18827
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2.18768
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.17022
SMAD2 SMAD family member 2 2.16047
TNPO3 transportin 3 2.1602
FASTKD5 FAST kinase domains 5 2.15679
RPL3 ribosomal protein L3 2.14616
SRSF9 serine/arginine-rich splicing factor 9 2.1432
JTB jumping translocation breakpoint 2.13914
RPL15 ribosomal protein L15 2.13805
PDF peptide deformylase (mitochondrial) 2.13719
AKAP10 A kinase (PRKA) anchor protein 10 2.13378
RPL6 ribosomal protein L6 2.11789
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.08302
EDF1 endothelial differentiation-related factor 1 2.06749
ERP29 endoplasmic reticulum protein 29 2.04045
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 2.03478
RNF114 ring finger protein 114 2.03454
RFXANK regulatory factor X-associated ankyrin-containing protein 2.01638
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.01608
SPAG8 sperm associated antigen 8 2.01398
ARF5 ADP-ribosylation factor 5 1.99315
PTEN phosphatase and tensin homolog 1.98566
TCF20 transcription factor 20 (AR1) 1.97412
MZT2A mitotic spindle organizing protein 2A 1.97214
RPL28 ribosomal protein L28 1.96165
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.95756
PANX1 pannexin 1 1.94692
UBE2Z ubiquitin-conjugating enzyme E2Z 1.94349
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.94228
TXNL4B thioredoxin-like 4B 1.93848
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.93767
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 1.92384
ARF6 ADP-ribosylation factor 6 1.92325
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.91835
COPS6 COP9 signalosome subunit 6 1.91746
NFU1 NFU1 iron-sulfur cluster scaffold 1.91721
NIP7 NIP7, nucleolar pre-rRNA processing protein 1.916
GANAB glucosidase, alpha; neutral AB 1.90054
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.89538
FABP6 fatty acid binding protein 6, ileal 1.89376
PREB prolactin regulatory element binding 1.89151
IRAK4 interleukin-1 receptor-associated kinase 4 1.8895
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.88572
SLC25A38 solute carrier family 25, member 38 1.88287
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 1.88163
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.87884
EIF3I eukaryotic translation initiation factor 3, subunit I 1.8764
RPL36AL ribosomal protein L36a-like 1.87452
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.86881
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 1.86613
FLAD1 flavin adenine dinucleotide synthetase 1 1.86266
ATPIF1 ATPase inhibitory factor 1 1.85957
ZNF510 zinc finger protein 510 1.85609
TSSC1 tumor suppressing subtransferable candidate 1 1.84925
MZT2B mitotic spindle organizing protein 2B 1.83886
ZNF672 zinc finger protein 672 1.83547
TGOLN2 trans-golgi network protein 2 1.8354
PGAP3 post-GPI attachment to proteins 3 1.8309
UQCRH ubiquinol-cytochrome c reductase hinge protein 1.82186
PITPNM3 PITPNM family member 3 1.82165
TMEM185B transmembrane protein 185B 1.81623
MAP2K6 mitogen-activated protein kinase kinase 6 1.81415
TOE1 target of EGR1, member 1 (nuclear) 1.81411
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 1.79193
DDR1 discoidin domain receptor tyrosine kinase 1 1.78797
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 1.78506
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.782
ISG20 interferon stimulated exonuclease gene 20kDa 1.77821
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.77639
PFKP phosphofructokinase, platelet 1.77364
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.76783
GMPPA GDP-mannose pyrophosphorylase A 1.75733
C14ORF169 chromosome 14 open reading frame 169 1.75443
MEA1 male-enhanced antigen 1 1.75412
DNAAF5 dynein, axonemal, assembly factor 5 1.75283
RPS9 ribosomal protein S9 1.74864
AFF2 AF4/FMR2 family, member 2 1.74731
MRPL40 mitochondrial ribosomal protein L40 1.74515
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.74473
SNHG3 small nucleolar RNA host gene 3 1.74349
SET SET nuclear proto-oncogene 1.73515
TMEM248 transmembrane protein 248 1.73393
RNMTL1 RNA methyltransferase like 1 1.72184
LAGE3 L antigen family, member 3 1.71926
RPL24 ribosomal protein L24 1.71473
TRMT5 tRNA methyltransferase 5 1.71384
ERCC6 excision repair cross-complementation group 6 1.7086
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.70511
IL20RB interleukin 20 receptor beta 1.70197
RPS4X ribosomal protein S4, X-linked 1.69958
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.69836
PFDN1 prefoldin subunit 1 1.69664
RPL22L1 ribosomal protein L22-like 1 1.69633
FNBP1 formin binding protein 1 1.69567
SHOX2 short stature homeobox 2 1.69353
ATG5 autophagy related 5 1.69326
CDC42SE1 CDC42 small effector 1 1.68935
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 1.68852
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.68668
ZNF430 zinc finger protein 430 1.68005
ATP5G2P1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) pseudogene 1 1.67109
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.66976
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.66786
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.66778
DDT D-dopachrome tautomerase 1.66655
GCC1 GRIP and coiled-coil domain containing 1 1.66545
MED1 mediator complex subunit 1 1.66448
TSPYL1 TSPY-like 1 1.66416
USP1 ubiquitin specific peptidase 1 1.65329
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 1.65308
C12ORF49 chromosome 12 open reading frame 49 1.6525
PDCD11 programmed cell death 11 1.65173
TCEA1 transcription elongation factor A (SII), 1 1.64875
SMG9 SMG9 nonsense mediated mRNA decay factor 1.64725
RPL30 ribosomal protein L30 1.64704
RPL13 ribosomal protein L13 1.64621
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.64457
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.64448
FAM134A family with sequence similarity 134, member A 1.64398
SREK1IP1 SREK1-interacting protein 1 1.64319
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.6426
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 1.64205
RAN RAN, member RAS oncogene family 1.63645
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 1.63561
PEBP1 phosphatidylethanolamine binding protein 1 1.63275
ALPI alkaline phosphatase, intestinal 1.63173
SEC16A SEC16 homolog A (S. cerevisiae) 1.63125
ATF6B activating transcription factor 6 beta 1.63059
RPS27L ribosomal protein S27-like 1.62645
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.6255
INPPL1 inositol polyphosphate phosphatase-like 1 1.62277
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.61959
RING1 ring finger protein 1 1.61921
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.61718
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 1.61683
SON SON DNA binding protein 1.61432
NSUN3 NOP2/Sun domain family, member 3 1.61425
ITPK1 inositol-tetrakisphosphate 1-kinase 1.61421
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.61163
SOD1 superoxide dismutase 1, soluble 1.60687
SFTPC surfactant protein C 1.60648
PARP1 poly (ADP-ribose) polymerase 1 1.60532
KLF9 Kruppel-like factor 9 1.60434
BTF3 basic transcription factor 3 1.60281
FAM53B family with sequence similarity 53, member B 1.60161
ATXN7L3B ataxin 7-like 3B 1.6011
C19ORF40 chromosome 19 open reading frame 40 1.60072
RBM3 RNA binding motif (RNP1, RRM) protein 3 1.60023
RPS7 ribosomal protein S7 1.59747
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 1.59741
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.59516
THADA thyroid adenoma associated 1.59455
FEM1B fem-1 homolog b (C. elegans) 1.59001
GTF2A2 general transcription factor IIA, 2, 12kDa 1.58889
RPL26 ribosomal protein L26 1.58722
UBE3C ubiquitin protein ligase E3C 1.5858
RPL27A ribosomal protein L27a 1.58308
RPS21 ribosomal protein S21 1.58303
EBNA1BP2 EBNA1 binding protein 2 1.58265
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.58252
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.58021
SUN2 Sad1 and UNC84 domain containing 2 1.57487
NCK2 NCK adaptor protein 2 1.57463
IFT20 intraflagellar transport 20 1.57366
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.57253
ANXA11 annexin A11 1.57161
TERF2IP telomeric repeat binding factor 2, interacting protein 1.57043
NGLY1 N-glycanase 1 1.56841
CHST10 carbohydrate sulfotransferase 10 1.55974
GGT1 gamma-glutamyltransferase 1 1.55908
PPAT phosphoribosyl pyrophosphate amidotransferase 1.55806
RPL9 ribosomal protein L9 1.55029
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.54957
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.54742
STOML2 stomatin (EPB72)-like 2 1.54443
SIVA1 SIVA1, apoptosis-inducing factor 1.54343
ZNHIT3 zinc finger, HIT-type containing 3 1.53748
PTRH2 peptidyl-tRNA hydrolase 2 1.53661
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 1.53534
PLCL2 phospholipase C-like 2 1.53399
FBRS fibrosin 1.53244
ACAA1 acetyl-CoA acyltransferase 1 1.53185
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 1.5309
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.52888
MED22 mediator complex subunit 22 1.52658
IFT57 intraflagellar transport 57 1.51195
MCM2 minichromosome maintenance complex component 2 1.51092
PMPCA peptidase (mitochondrial processing) alpha 1.51081
RPL35 ribosomal protein L35 1.50969
CHMP1B charged multivesicular body protein 1B 1.50846
SDF2 stromal cell-derived factor 2 1.50568
AP5M1 adaptor-related protein complex 5, mu 1 subunit 1.50497
TRIM24 tripartite motif containing 24 1.50466
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.5019
IDE insulin-degrading enzyme 1.49981
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 1.49891
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.49846
SNRPE small nuclear ribonucleoprotein polypeptide E 1.49783
LY6G5C lymphocyte antigen 6 complex, locus G5C 1.49671
UMPS uridine monophosphate synthetase 1.49598
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1.4908
RBM7 RNA binding motif protein 7 1.4876
YY1 YY1 transcription factor 1.48686
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.48519
CLIC1 chloride intracellular channel 1 1.48341
SNX15 sorting nexin 15 1.48051
NGRN neugrin, neurite outgrowth associated 1.47797
KIF3B kinesin family member 3B 1.47703
ORAI2 ORAI calcium release-activated calcium modulator 2 1.47569
SNRPA small nuclear ribonucleoprotein polypeptide A 1.47368
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 1.47258
CYB561D2 cytochrome b561 family, member D2 1.47074
MAPK6 mitogen-activated protein kinase 6 1.47022
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.46998
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.46995
GLRX3 glutaredoxin 3 1.46978
COX17 COX17 cytochrome c oxidase copper chaperone 1.46944
LPAR2 lysophosphatidic acid receptor 2 1.46872
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.46847
SNRPF small nuclear ribonucleoprotein polypeptide F 1.46715
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1.46702
NOL7 nucleolar protein 7, 27kDa 1.46178
GTPBP6 GTP binding protein 6 (putative) 1.46106
EIF3C eukaryotic translation initiation factor 3, subunit C 1.45979
RPL38 ribosomal protein L38 1.45426
MUS81 MUS81 structure-specific endonuclease subunit 1.45144
TRIOBP TRIO and F-actin binding protein 1.45109
PRR13 proline rich 13 1.44901
PRDX6 peroxiredoxin 6 1.44804
DYNLRB1 dynein, light chain, roadblock-type 1 1.44716
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 1.44594
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.44381
RALGDS ral guanine nucleotide dissociation stimulator 1.4434
NUP214 nucleoporin 214kDa 1.44095
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.44001
PRAMEF11 PRAME family member 11 1.43921
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.43851
CLEC2D C-type lectin domain family 2, member D 1.43782
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.43739
CDCA4 cell division cycle associated 4 1.43494
ETHE1 ethylmalonic encephalopathy 1 1.43459
RPL37A ribosomal protein L37a 1.43451
GLO1 glyoxalase I 1.43271
WBSCR22 Williams Beuren syndrome chromosome region 22 1.43225
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 1.43221
LAS1L LAS1-like (S. cerevisiae) 1.43051
MPC1 mitochondrial pyruvate carrier 1 1.42955
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.42711
PA2G4 proliferation-associated 2G4, 38kDa 1.42663
FLNC filamin C, gamma 1.42594
PPAP2A phosphatidic acid phosphatase type 2A 1.42582
EGLN1 egl-9 family hypoxia-inducible factor 1 1.42492
NOP56 NOP56 ribonucleoprotein 1.42449
DCAF6 DDB1 and CUL4 associated factor 6 1.42266
ZNF394 zinc finger protein 394 1.4206
ECH1 enoyl CoA hydratase 1, peroxisomal 1.4193
ADAT1 adenosine deaminase, tRNA-specific 1 1.41838
TRMT61A tRNA methyltransferase 61A 1.41696
RSL1D1 ribosomal L1 domain containing 1 1.41668
ISCU iron-sulfur cluster assembly enzyme 1.41557
PMVK phosphomevalonate kinase 1.41489
ABI2 abl-interactor 2 1.41445
GDF11 growth differentiation factor 11 1.41395
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 1.41355
FUS FUS RNA binding protein 1.41345
MOBP myelin-associated oligodendrocyte basic protein 1.41336
GRAMD1B GRAM domain containing 1B 1.41251
MYDGF myeloid-derived growth factor 1.41148
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 1.41127
NCAPD2 non-SMC condensin I complex, subunit D2 1.41029
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 1.40863
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.40834
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 1.4048
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.40264
SSRP1 structure specific recognition protein 1 1.4024
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.39986

decreased expression

Symbol Name Standardized Value
RPL23A ribosomal protein L23a -3.63308
RPLP1 ribosomal protein, large, P1 -3.36471
RPL39 ribosomal protein L39 -3.30406
TPT1 tumor protein, translationally-controlled 1 -3.09834
FOXJ2 forkhead box J2 -3.05897
RPL41 ribosomal protein L41 -3.03633
MKRN1 makorin ring finger protein 1 -2.96472
RPL34 ribosomal protein L34 -2.83664
TJAP1 tight junction associated protein 1 (peripheral) -2.78894
RPS29 ribosomal protein S29 -2.7348
POM121 POM121 transmembrane nucleoporin -2.68253
RPLP0 ribosomal protein, large, P0 -2.67688
HLA-A major histocompatibility complex, class I, A -2.65597
RTN4 reticulon 4 -2.64926
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.55392
RPL19 ribosomal protein L19 -2.51169
B2M beta-2-microglobulin -2.44231
PTPRC protein tyrosine phosphatase, receptor type, C -2.43216
TARDBP TAR DNA binding protein -2.38932
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -2.37601
GAK cyclin G associated kinase -2.36688
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.35428
TPP2 tripeptidyl peptidase II -2.35428
C15ORF39 chromosome 15 open reading frame 39 -2.34884
RPS20 ribosomal protein S20 -2.34136
RAB14 RAB14, member RAS oncogene family -2.33765
CALR calreticulin -2.31437
PPP6C protein phosphatase 6, catalytic subunit -2.30402
ANAPC2 anaphase promoting complex subunit 2 -2.29598
OTUD4 OTU deubiquitinase 4 -2.28573
RPS3 ribosomal protein S3 -2.26634
PTMA prothymosin, alpha -2.25653
SEC63 SEC63 homolog (S. cerevisiae) -2.25038
ADNP activity-dependent neuroprotector homeobox -2.24668
GAPVD1 GTPase activating protein and VPS9 domains 1 -2.24183
EP300 E1A binding protein p300 -2.24034
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.23093
SENP5 SUMO1/sentrin specific peptidase 5 -2.20751
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.18081
GLTSCR2 glioma tumor suppressor candidate region gene 2 -2.13738
UBE2B ubiquitin-conjugating enzyme E2B -2.13215
OSBPL2 oxysterol binding protein-like 2 -2.10046
ADSS adenylosuccinate synthase -2.09313
IQSEC1 IQ motif and Sec7 domain 1 -2.07442
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.07293
DNPEP aspartyl aminopeptidase -2.07151
PROSER1 proline and serine rich 1 -2.06919
NCOR1 nuclear receptor corepressor 1 -2.0673
TRIM38 tripartite motif containing 38 -2.0658
C11ORF58 chromosome 11 open reading frame 58 -2.05851
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -2.05122
GPR137 G protein-coupled receptor 137 -2.03837
MID1IP1 MID1 interacting protein 1 -2.02426
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -2.00022
UBAP2L ubiquitin associated protein 2-like -1.99385
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.97079
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -1.96312
AMPD2 adenosine monophosphate deaminase 2 -1.94407
CTSO cathepsin O -1.94062
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -1.937
C17ORF85 chromosome 17 open reading frame 85 -1.93171
CNOT7 CCR4-NOT transcription complex, subunit 7 -1.93119
MECP2 methyl CpG binding protein 2 -1.92818
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -1.92706
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.92173
MADD MAP-kinase activating death domain -1.91729
JAK1 Janus kinase 1 -1.91177
U2AF2 U2 small nuclear RNA auxiliary factor 2 -1.90589
KHNYN KH and NYN domain containing -1.8759
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.87272
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -1.85954
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -1.85696
PRPF4 pre-mRNA processing factor 4 -1.85515
STAG2 stromal antigen 2 -1.8542
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -1.84811
MTA1 metastasis associated 1 -1.84467
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.84184
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -1.83849
TMSB10 thymosin beta 10 -1.83718
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -1.8287
TCP1 t-complex 1 -1.82349
TMEM214 transmembrane protein 214 -1.82101
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -1.79303
USP47 ubiquitin specific peptidase 47 -1.78598
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -1.78476
SSR4 signal sequence receptor, delta -1.78325
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -1.77682
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 -1.77164
RPL29 ribosomal protein L29 -1.7707
HMGB1 high mobility group box 1 -1.77017
NUP98 nucleoporin 98kDa -1.76902
RUNX1-IT1 RUNX1 intronic transcript 1 -1.76641
STX12 syntaxin 12 -1.76066
XPO7 exportin 7 -1.76037
OXSR1 oxidative stress responsive 1 -1.75859
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -1.75747
HLA-F major histocompatibility complex, class I, F -1.75406
DKC1 dyskeratosis congenita 1, dyskerin -1.75262
MAP2K4 mitogen-activated protein kinase kinase 4 -1.7513
AGK acylglycerol kinase -1.74102
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -1.74059
MAGED2 melanoma antigen family D2 -1.73915
CAST calpastatin -1.73398
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.73188
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa -1.72751
THOC2 THO complex 2 -1.71673
MCAM melanoma cell adhesion molecule -1.7119
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.7073
PRRC2B proline-rich coiled-coil 2B -1.70126
IFI44 interferon-induced protein 44 -1.69715
MR1 major histocompatibility complex, class I-related -1.69035
RPS28 ribosomal protein S28 -1.68754
SETD5 SET domain containing 5 -1.68562
DPY19L1 dpy-19-like 1 (C. elegans) -1.68222
MINK1 misshapen-like kinase 1 -1.68219
CLINT1 clathrin interactor 1 -1.67564
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.67174
PHIP pleckstrin homology domain interacting protein -1.66968
MDC1 mediator of DNA-damage checkpoint 1 -1.66809
PRDM10 PR domain containing 10 -1.6663
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -1.66591
RBM25 RNA binding motif protein 25 -1.66244
RHOG ras homolog family member G -1.66219
PHF20 PHD finger protein 20 -1.66128
IVNS1ABP influenza virus NS1A binding protein -1.65967
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.65882
SGSM2 small G protein signaling modulator 2 -1.65737
TRIM26 tripartite motif containing 26 -1.6569
TMEM60 transmembrane protein 60 -1.65615
CIDEB cell death-inducing DFFA-like effector b -1.63939
RAB22A RAB22A, member RAS oncogene family -1.63701
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -1.63586
HSPA8 heat shock 70kDa protein 8 -1.63456
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.62898
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.62506
BSDC1 BSD domain containing 1 -1.62175
TRIP12 thyroid hormone receptor interactor 12 -1.61885
ARF4 ADP-ribosylation factor 4 -1.61822
USP21 ubiquitin specific peptidase 21 -1.60955
RRBP1 ribosome binding protein 1 -1.60834
AIM1 absent in melanoma 1 -1.60786
KAT6A K(lysine) acetyltransferase 6A -1.60678
FAM160B2 family with sequence similarity 160, member B2 -1.60658
FBP1 fructose-1,6-bisphosphatase 1 -1.60542
TRIM62 tripartite motif containing 62 -1.59942
KPNA6 karyopherin alpha 6 (importin alpha 7) -1.59504
HYOU1 hypoxia up-regulated 1 -1.58655
QRICH1 glutamine-rich 1 -1.57987
TMEM41B transmembrane protein 41B -1.57799
MRPS2 mitochondrial ribosomal protein S2 -1.57675
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.57536
DCAF8 DDB1 and CUL4 associated factor 8 -1.57411
WAS Wiskott-Aldrich syndrome -1.57236
BID BH3 interacting domain death agonist -1.56937
DND1 DND microRNA-mediated repression inhibitor 1 -1.56825
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -1.56517
XBP1 X-box binding protein 1 -1.56506
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -1.56103
CCR9 chemokine (C-C motif) receptor 9 -1.56017
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -1.56003
KLHDC3 kelch domain containing 3 -1.55839
TNIK TRAF2 and NCK interacting kinase -1.55502
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -1.55485
GOSR1 golgi SNAP receptor complex member 1 -1.55263
ACTG1 actin gamma 1 -1.55149
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.54917
DCAF15 DDB1 and CUL4 associated factor 15 -1.54792
MICA MHC class I polypeptide-related sequence A -1.54711
BCORL1 BCL6 corepressor-like 1 -1.54342
NLRP1 NLR family, pyrin domain containing 1 -1.54295
OVGP1 oviductal glycoprotein 1, 120kDa -1.54225
MAP7D1 MAP7 domain containing 1 -1.54005
SRP54 signal recognition particle 54kDa -1.53688
MIA3 melanoma inhibitory activity family, member 3 -1.53531
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -1.53288
HLA-E major histocompatibility complex, class I, E -1.53249
ELMO2 engulfment and cell motility 2 -1.5324
FMNL1 formin-like 1 -1.52949
RBBP7 retinoblastoma binding protein 7 -1.52553
FURIN furin (paired basic amino acid cleaving enzyme) -1.52511
DYNLT3 dynein, light chain, Tctex-type 3 -1.52439
ADIPOR1 adiponectin receptor 1 -1.52391
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -1.52232
PRPF4B pre-mRNA processing factor 4B -1.51918
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.51837
N4BP1 NEDD4 binding protein 1 -1.51549
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -1.51547
PTPRF protein tyrosine phosphatase, receptor type, F -1.51525
USP24 ubiquitin specific peptidase 24 -1.51216
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -1.50837
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.50825
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -1.50811
C1ORF27 chromosome 1 open reading frame 27 -1.50786
VIM vimentin -1.50183
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -1.50139
GSTM1 glutathione S-transferase mu 1 -1.49962
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -1.49884
SART3 squamous cell carcinoma antigen recognized by T cells 3 -1.49599
RBM23 RNA binding motif protein 23 -1.49437
ARID1A AT rich interactive domain 1A (SWI-like) -1.49065
EPOR erythropoietin receptor -1.48954
CEP57 centrosomal protein 57kDa -1.48674
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -1.48622
CELA3A chymotrypsin-like elastase family, member 3A -1.48596
ARNTL aryl hydrocarbon receptor nuclear translocator-like -1.48542
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.48368
SCAPER S-phase cyclin A-associated protein in the ER -1.48358
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.47987
EML3 echinoderm microtubule associated protein like 3 -1.47943
SMC3 structural maintenance of chromosomes 3 -1.47916
ZNF419 zinc finger protein 419 -1.47891
LPPR2 lipid phosphate phosphatase-related protein type 2 -1.47395
NBAS neuroblastoma amplified sequence -1.47024
SASH3 SAM and SH3 domain containing 3 -1.46929
FAM98A family with sequence similarity 98, member A -1.4667
POLB polymerase (DNA directed), beta -1.46641
ROGDI rogdi homolog (Drosophila) -1.46609
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -1.46491
SLC35B1 solute carrier family 35, member B1 -1.46214
RPS24 ribosomal protein S24 -1.46107
AQP6 aquaporin 6, kidney specific -1.4592
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -1.4576
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.45177
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G -1.45172
GOLGA2 golgin A2 -1.44899
KIAA0232 KIAA0232 -1.44482
SEC24C SEC24 family member C -1.44472
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -1.43987
NOD1 nucleotide-binding oligomerization domain containing 1 -1.43681
TNPO1 transportin 1 -1.43365
UXS1 UDP-glucuronate decarboxylase 1 -1.43349
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -1.43337
FAM50A family with sequence similarity 50, member A -1.43122
PTGER3 prostaglandin E receptor 3 (subtype EP3) -1.43072
ARMCX6 armadillo repeat containing, X-linked 6 -1.4263
ULK2 unc-51 like autophagy activating kinase 2 -1.42259
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.41908
TM9SF2 transmembrane 9 superfamily member 2 -1.41721
SSFA2 sperm specific antigen 2 -1.41407
PIAS3 protein inhibitor of activated STAT, 3 -1.40713
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.40672
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -1.40364
DPP8 dipeptidyl-peptidase 8 -1.40248
SUMO4 small ubiquitin-like modifier 4 -1.40149
PUM1 pumilio RNA-binding family member 1 -1.40107
NACA nascent polypeptide-associated complex alpha subunit -1.39997
YTHDC2 YTH domain containing 2 -1.39874
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.39727
NCOA2 nuclear receptor coactivator 2 -1.3971
RGS6 regulator of G-protein signaling 6 -1.39566
BAZ1A bromodomain adjacent to zinc finger domain, 1A -1.39525
PAPOLG poly(A) polymerase gamma -1.39156
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.39088
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.38921
PIH1D1 PIH1 domain containing 1 -1.38866
CUX1 cut-like homeobox 1 -1.38807
RASA2 RAS p21 protein activator 2 -1.38793
CUL5 cullin 5 -1.38608
ADRBK1 adrenergic, beta, receptor kinase 1 -1.38357
CXORF40B chromosome X open reading frame 40B -1.38234
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.3797
SNTA1 syntrophin, alpha 1 -1.37806
MED13L mediator complex subunit 13-like -1.37465
DARS aspartyl-tRNA synthetase -1.37416
SRC SRC proto-oncogene, non-receptor tyrosine kinase -1.37411
ZNF26 zinc finger protein 26 -1.37311
ZNF304 zinc finger protein 304 -1.37069
ZNF500 zinc finger protein 500 -1.36982
APOL3 apolipoprotein L, 3 -1.36807
CKAP5 cytoskeleton associated protein 5 -1.36529
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -1.36475
GSTM2 glutathione S-transferase mu 2 (muscle) -1.36306
NFRKB nuclear factor related to kappaB binding protein -1.36187
TYMP thymidine phosphorylase -1.36145
CIZ1 CDKN1A interacting zinc finger protein 1 -1.36116
KDM5B lysine (K)-specific demethylase 5B -1.35924
PAPD7 PAP associated domain containing 7 -1.35887
RCAN1 regulator of calcineurin 1 -1.35772
TTC3 tetratricopeptide repeat domain 3 -1.35675
KPNB1 karyopherin (importin) beta 1 -1.35612
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.35589
COPB1 coatomer protein complex, subunit beta 1 -1.35466
ACAD8 acyl-CoA dehydrogenase family, member 8 -1.35426
NIPBL Nipped-B homolog (Drosophila) -1.35265
YIPF3 Yip1 domain family, member 3 -1.35089
BRD1 bromodomain containing 1 -1.35028
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -1.34903
CS citrate synthase -1.34732
TREX2 three prime repair exonuclease 2 -1.34613
NF1 neurofibromin 1 -1.34431
TRIM3 tripartite motif containing 3 -1.34323
SYNJ1 synaptojanin 1 -1.34304
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.34205
AGGF1 angiogenic factor with G patch and FHA domains 1 -1.34195
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -1.34178
JARID2 jumonji, AT rich interactive domain 2 -1.34127
SARS seryl-tRNA synthetase -1.34126
WAC WW domain containing adaptor with coiled-coil -1.34058
MLX MLX, MAX dimerization protein -1.33935
FBXO42 F-box protein 42 -1.33849