Atrioventricular Block Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A heart conduction disease that is characterized by the impairment of the conduction between the atria and ventricles of the heart. (Human Disease Ontology, DOID_0050820)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D054537
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Genes

507 genes/proteins associated with the disease Atrioventricular Block from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.48713
TNF tumor necrosis factor 2.4415
MAPK1 mitogen-activated protein kinase 1 2.43067
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.42495
FOS FBJ murine osteosarcoma viral oncogene homolog 2.42352
MAPK3 mitogen-activated protein kinase 3 2.42315
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.3847
IL6 interleukin 6 2.37463
BCL2 B-cell CLL/lymphoma 2 2.33904
BAX BCL2-associated X protein 2.33227
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.32309
CAT catalase 2.31927
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.29743
IL1B interleukin 1, beta 2.28292
FAS Fas cell surface death receptor 2.26875
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.2599
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.19649
VEGFA vascular endothelial growth factor A 2.18135
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.17796
NPPA natriuretic peptide A 2.15598
REN renin 2.15527
CXCL8 chemokine (C-X-C motif) ligand 8 2.14662
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.13381
NOS2 nitric oxide synthase 2, inducible 2.11659
IL10 interleukin 10 2.11482
PRL prolactin 2.11163
IFNG interferon, gamma 2.10807
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.09695
HMOX1 heme oxygenase 1 2.09452
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.08989
EGR1 early growth response 1 2.08764
BDNF brain-derived neurotrophic factor 2.08669
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.08645
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.08356
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.07263
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.0644
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.05633
BCL2L1 BCL2-like 1 2.03939
GSTP1 glutathione S-transferase pi 1 2.02971
JUN jun proto-oncogene 2.02782
TP53 tumor protein p53 2.01773
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.008
MMP9 matrix metallopeptidase 9 1.99076
SOD2 superoxide dismutase 2, mitochondrial 1.972
ADRB1 adrenoceptor beta 1 1.97141
TGFB1 transforming growth factor, beta 1 1.97038
NPPB natriuretic peptide B 1.96343
FASLG Fas ligand (TNF superfamily, member 6) 1.9495
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.94595
NOS3 nitric oxide synthase 3 (endothelial cell) 1.94595
EGFR epidermal growth factor receptor 1.94595
NPY neuropeptide Y 1.94406
ADRB2 adrenoceptor beta 2, surface 1.93536
NUPR1 nuclear protein, transcriptional regulator, 1 1.93088
EDN1 endothelin 1 1.92438
PARP1 poly (ADP-ribose) polymerase 1 1.91797
DDIT3 DNA-damage-inducible transcript 3 1.90771
CCL2 chemokine (C-C motif) ligand 2 1.90275
CRH corticotropin releasing hormone 1.88995
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.8826
MAPK14 mitogen-activated protein kinase 14 1.88092
IL2 interleukin 2 1.87393
DRD1 dopamine receptor D1 1.87244
ICAM1 intercellular adhesion molecule 1 1.8684
TH tyrosine hydroxylase 1.86027
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.84782
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.84055
IL4 interleukin 4 1.83113
SOD1 superoxide dismutase 1, soluble 1.83042
CCND1 cyclin D1 1.82464
IL12B interleukin 12B 1.81921
GFAP glial fibrillary acidic protein 1.81574
MAPK8 mitogen-activated protein kinase 8 1.8128
MPO myeloperoxidase 1.79981
POMC proopiomelanocortin 1.79121
CYCS cytochrome c, somatic 1.77686
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.75895
DRD2 dopamine receptor D2 1.75777
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.7542
IL1A interleukin 1, alpha 1.75281
RYR2 ryanodine receptor 2 (cardiac) 1.74681
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.74119
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.73577
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.73292
CREB1 cAMP responsive element binding protein 1 1.72738
INS insulin 1.72738
VCAM1 vascular cell adhesion molecule 1 1.72405
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.72384
TAC1 tachykinin, precursor 1 1.71789
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.71789
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.71214
CALCA calcitonin-related polypeptide alpha 1.71009
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.71009
AVP arginine vasopressin 1.70988
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.70285
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.69125
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.68761
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.6857
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.68337
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.67633
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.67611
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.65621
COL1A1 collagen, type I, alpha 1 1.65511
CFLAR CASP8 and FADD-like apoptosis regulator 1.65402
DUSP1 dual specificity phosphatase 1 1.65249
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.65159
GAL galanin/GMAP prepropeptide 1.64123
HSPB1 heat shock 27kDa protein 1 1.63877
MMP2 matrix metallopeptidase 2 1.63384
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.63027
ACHE acetylcholinesterase (Yt blood group) 1.62512
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.62335
NGF nerve growth factor (beta polypeptide) 1.61874
MAP2K1 mitogen-activated protein kinase kinase 1 1.61874
IL12A interleukin 12A 1.61575
HPCA hippocalcin 1.6146
INHBE inhibin, beta E 1.61154
IL18 interleukin 18 1.60337
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.60012
GJA1 gap junction protein, alpha 1, 43kDa 1.59521
PRKCE protein kinase C, epsilon 1.5903
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.58374
PRKCD protein kinase C, delta 1.57829
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.57641
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.5721
ODC1 ornithine decarboxylase 1 1.57138
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.57138
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.56899
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.5673
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.56141
APP amyloid beta (A4) precursor protein 1.55378
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.55035
MAOA monoamine oxidase A 1.54062
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.54062
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.53868
ARRB2 arrestin, beta 2 1.52161
JUNB jun B proto-oncogene 1.52111
EGR2 early growth response 2 1.52061
CTSB cathepsin B 1.51986
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.5181
C10ORF10 chromosome 10 open reading frame 10 1.51734
IGF1 insulin-like growth factor 1 (somatomedin C) 1.5138
ACTB actin, beta 1.5138
ATF3 activating transcription factor 3 1.5123
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.4989
CTSD cathepsin D 1.49787
MCL1 myeloid cell leukemia 1 1.4966
GAP43 growth associated protein 43 1.49584
PENK proenkephalin 1.49096
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.49019
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.49019
HOMER1 homer scaffolding protein 1 1.48761
APAF1 apoptotic peptidase activating factor 1 1.48608
GSTM1 glutathione S-transferase mu 1 1.4817
F2 coagulation factor II (thrombin) 1.47711
GSK3B glycogen synthase kinase 3 beta 1.46807
GH1 growth hormone 1 1.46781
CREM cAMP responsive element modulator 1.46621
KLF4 Kruppel-like factor 4 (gut) 1.46621
CCND3 cyclin D3 1.45883
TIMP1 TIMP metallopeptidase inhibitor 1 1.4567
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.45484
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.4522
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.45009
BIRC5 baculoviral IAP repeat containing 5 1.44899
CCL3 chemokine (C-C motif) ligand 3 1.44599
BAK1 BCL2-antagonist/killer 1 1.44572
SELL selectin L 1.44193
FSHB follicle stimulating hormone, beta polypeptide 1.44084
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.44029
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.43864
GADD45A growth arrest and DNA-damage-inducible, alpha 1.43782
CNR1 cannabinoid receptor 1 (brain) 1.437
HSPA8 heat shock 70kDa protein 8 1.43401
CASP12 caspase 12 (gene/pseudogene) 1.42994
FN1 fibronectin 1 1.42428
ARC activity-regulated cytoskeleton-associated protein 1.42101
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.4202
APOE apolipoprotein E 1.41884
ATM ATM serine/threonine kinase 1.41424
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.41313
CES2 carboxylesterase 2 1.40705
GPX1 glutathione peroxidase 1 1.39952
SQSTM1 sequestosome 1 1.39841
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.39451
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.39226
STAR steroidogenic acute regulatory protein 1.38946
PRKCB protein kinase C, beta 1.38724
GSR glutathione reductase 1.38441
HSPA1A heat shock 70kDa protein 1A 1.37705
ADRA1B adrenoceptor alpha 1B 1.3759
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.37561
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.37275
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.37047
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.3699
SPP1 secreted phosphoprotein 1 1.36933
MAP2K2 mitogen-activated protein kinase kinase 2 1.36619
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.36447
KDR kinase insert domain receptor 1.36447
S100A4 S100 calcium binding protein A4 1.36104
IRS1 insulin receptor substrate 1 1.35934
BID BH3 interacting domain death agonist 1.35906
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.35763
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.35531
BECN1 beclin 1, autophagy related 1.35531
ALB albumin 1.35299
PRKCA protein kinase C, alpha 1.35184
CHEK2 checkpoint kinase 2 1.34606
CRP C-reactive protein, pentraxin-related 1.34314
MSMO1 methylsterol monooxygenase 1 1.34111
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.33966
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.3385
CDK2 cyclin-dependent kinase 2 1.33701
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.33672
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.33553
CTGF connective tissue growth factor 1.33434
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.3314
MMP13 matrix metallopeptidase 13 1.32905
F3 coagulation factor III (thromboplastin, tissue factor) 1.32696
PTEN phosphatase and tensin homolog 1.32577
PLAT plasminogen activator, tissue 1.32577
OXT oxytocin/neurophysin I prepropeptide 1.32488
METRN meteorin, glial cell differentiation regulator 1.32458
E2F1 E2F transcription factor 1 1.3228
GATA4 GATA binding protein 4 1.3228
HPN hepsin 1.32132
GNAS GNAS complex locus 1.31956
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 1.31686
CTSL cathepsin L 1.31686
BTG2 BTG family, member 2 1.31656
MAPT microtubule-associated protein tau 1.31656
VIM vimentin 1.31416
CLU clusterin 1.31416
GAST gastrin 1.31237
FGF2 fibroblast growth factor 2 (basic) 1.31237
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.31148
PRDX2 peroxiredoxin 2 1.30635
ADORA1 adenosine A1 receptor 1.30635
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.30421
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.3039
CDK1 cyclin-dependent kinase 1 1.3036
TIMP2 TIMP metallopeptidase inhibitor 2 1.30026
NTF3 neurotrophin 3 1.29843
BDKRB2 bradykinin receptor B2 1.29843
PHYH phytanoyl-CoA 2-hydroxylase 1.29657
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.29626
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.2944
FNDC4 fibronectin type III domain containing 4 1.2941
GRM1 glutamate receptor, metabotropic 1 1.28703
ANGPT2 angiopoietin 2 1.28703
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.28641
CALR calreticulin 1.2861
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.28364
LEP leptin 1.28241
RGS2 regulator of G-protein signaling 2 1.28119
PLAU plasminogen activator, urokinase 1.27875
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.27875
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.27875
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.27875
STMN1 stathmin 1 1.27657
POR P450 (cytochrome) oxidoreductase 1.27255
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.27255
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.27255
CXCL10 chemokine (C-X-C motif) ligand 10 1.27101
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.26917
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.26052
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.26052
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.26021
MAPK9 mitogen-activated protein kinase 9 1.25776
DHCR24 24-dehydrocholesterol reductase 1.254
LDLR low density lipoprotein receptor 1.25307
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.2509
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.24843
PPARA peroxisome proliferator-activated receptor alpha 1.24687
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.24528
ANXA1 annexin A1 1.24433
TNNI3 troponin I type 3 (cardiac) 1.23993
NEFH neurofilament, heavy polypeptide 1.23962
COL3A1 collagen, type III, alpha 1 1.23775
ADORA2A adenosine A2a receptor 1.2368
GCG glucagon 1.2368
LIF leukemia inhibitory factor 1.2368
ERP29 endoplasmic reticulum protein 29 1.23616
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.23584
IL1RN interleukin 1 receptor antagonist 1.23552
OPRM1 opioid receptor, mu 1 1.2336
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.23328
MMP1 matrix metallopeptidase 1 1.23042
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.22727
NOX4 NADPH oxidase 4 1.22534
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.22534
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.22534
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.22371
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.22209
H2AFX H2A histone family, member X 1.22209
G6PD glucose-6-phosphate dehydrogenase 1.22048
TRH thyrotropin-releasing hormone 1.22048
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.21823
TLR4 toll-like receptor 4 1.21695
CXCR4 chemokine (C-X-C motif) receptor 4 1.21663
ADCY5 adenylate cyclase 5 1.21271
NFE2L2 nuclear factor, erythroid 2-like 2 1.21076
MEF2C myocyte enhancer factor 2C 1.20946
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.20913
LCN2 lipocalin 2 1.20816
PCNA proliferating cell nuclear antigen 1.20622
FGFR1 fibroblast growth factor receptor 1 1.20622
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.20558
BCHE butyrylcholinesterase 1.20558
CD40LG CD40 ligand 1.20558
TFRC transferrin receptor 1.20394
TAGLN transgelin 1.20361
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.20196
RBL2 retinoblastoma-like 2 1.20196
PER1 period circadian clock 1 1.20196
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 1.20163
SREBF1 sterol regulatory element binding transcription factor 1 1.20064
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.19933
PIR pirin (iron-binding nuclear protein) 1.19835
CAV1 caveolin 1, caveolae protein, 22kDa 1.19802
CD14 CD14 molecule 1.19607
EIF5 eukaryotic translation initiation factor 5 1.19477
CHAT choline O-acetyltransferase 1.19477
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.19345
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.19345
RYR3 ryanodine receptor 3 1.19279
IGF1R insulin-like growth factor 1 receptor 1.19213
E2F3 E2F transcription factor 3 1.19113
UBC ubiquitin C 1.18783
SCN5A sodium channel, voltage gated, type V alpha subunit 1.1862
TJP1 tight junction protein 1 1.18554
S100A9 S100 calcium binding protein A9 1.18326
ETFB electron-transfer-flavoprotein, beta polypeptide 1.18126
STIP1 stress-induced phosphoprotein 1 1.18093
CXCL2 chemokine (C-X-C motif) ligand 2 1.18093
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.18093
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.18026
S100A10 S100 calcium binding protein A10 1.17761
MAP2 microtubule-associated protein 2 1.17761
CP ceruloplasmin (ferroxidase) 1.17464
PECAM1 platelet/endothelial cell adhesion molecule 1 1.17431
LHB luteinizing hormone beta polypeptide 1.16799
EIF4E eukaryotic translation initiation factor 4E 1.16766
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.16633
ADRA2A adrenoceptor alpha 2A 1.16467
PLCG1 phospholipase C, gamma 1 1.16467
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.16467
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.16467
CD40 CD40 molecule, TNF receptor superfamily member 5 1.16368
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.16368
LDHA lactate dehydrogenase A 1.16368
FOSL2 FOS-like antigen 2 1.16137
CDC25A cell division cycle 25A 1.16137
NOS1 nitric oxide synthase 1 (neuronal) 1.16001
S100A8 S100 calcium binding protein A8 1.15899
PTK2B protein tyrosine kinase 2 beta 1.15797
EZR ezrin 1.15797
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.15729
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.15729
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.15661
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.15256
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.15256
EPHX2 epoxide hydrolase 2, cytoplasmic 1.15189
BBC3 BCL2 binding component 3 1.15189
GSTO1 glutathione S-transferase omega 1 1.1485
CYBB cytochrome b-245, beta polypeptide 1.14747
COMT catechol-O-methyltransferase 1.14713
S100B S100 calcium binding protein B 1.14541
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.14234
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.14234
PDYN prodynorphin 1.14234
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.14166
GCLM glutamate-cysteine ligase, modifier subunit 1.14166
CCNB1 cyclin B1 1.13793
RBBP4 retinoblastoma binding protein 4 1.13484
GSTT1 glutathione S-transferase theta 1 1.13484
ACO2 aconitase 2, mitochondrial 1.13347
NT5C1A 5'-nucleotidase, cytosolic IA 1.13313
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.13143
CYR61 cysteine-rich, angiogenic inducer, 61 1.13143
RRM2 ribonucleotide reductase M2 1.13143
TMEM97 transmembrane protein 97 1.13041
NINJ1 ninjurin 1 1.13041
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.13041
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.1294
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.12771
PHB prohibitin 1.12771
RB1 retinoblastoma 1 1.12737
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.12634
GRIK2 glutamate receptor, ionotropic, kainate 2 1.12564
UNG uracil-DNA glycosylase 1.12461
BAG1 BCL2-associated athanogene 1.12219
KIF3A kinesin family member 3A 1.11911
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.11877
INSIG1 insulin induced gene 1 1.11877
TGFB2 transforming growth factor, beta 2 1.11639
GEM GTP binding protein overexpressed in skeletal muscle 1.11396
ADRBK1 adrenergic, beta, receptor kinase 1 1.11325
PDE4B phosphodiesterase 4B, cAMP-specific 1.11325
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.11325
TOP2A topoisomerase (DNA) II alpha 170kDa 1.1129
BAD BCL2-associated agonist of cell death 1.11116
TSC22D3 TSC22 domain family, member 3 1.10769
FOXO1 forkhead box O1 1.10769
VIP vasoactive intestinal peptide 1.10631
SGK1 serum/glucocorticoid regulated kinase 1 1.10388
CRYAB crystallin, alpha B 1.10388
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.10211
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.10175
HRH1 histamine receptor H1 1.09963
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.09822
NRP1 neuropilin 1 1.09681
HRAS Harvey rat sarcoma viral oncogene homolog 1.09506
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.09119
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.09047
CHEK1 checkpoint kinase 1 1.08975
HSPE1 heat shock 10kDa protein 1 1.08868
ATF4 activating transcription factor 4 1.08762
FHL1 four and a half LIM domains 1 1.08337
F2R coagulation factor II (thrombin) receptor 1.08091
EGR3 early growth response 3 1.07947
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.07804
CD44 CD44 molecule (Indian blood group) 1.07768
DDIT4 DNA-damage-inducible transcript 4 1.07589
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.07234
MMP3 matrix metallopeptidase 3 1.07199
FGFR2 fibroblast growth factor receptor 2 1.07057
BMP4 bone morphogenetic protein 4 1.07057
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.06881
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.06881
NES nestin 1.06881
FOLR1 folate receptor 1 (adult) 1.06515
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.06515
COL1A2 collagen, type I, alpha 2 1.06442
DPYSL3 dihydropyrimidinase-like 3 1.0608
CYC1 cytochrome c-1 1.0608
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.0608
LOX lysyl oxidase 1.06044
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.05793
EDNRA endothelin receptor type A 1.05573
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.05573
ADCY7 adenylate cyclase 7 1.05573
RGS4 regulator of G-protein signaling 4 1.05498
CCNF cyclin F 1.05498
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.05498
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.05312
ACTA2 actin, alpha 2, smooth muscle, aorta 1.052
TKT transketolase 1.05126
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.05015
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.04831
MYL9 myosin, light chain 9, regulatory 1.04831
HBEGF heparin-binding EGF-like growth factor 1.04831
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.04794
MICB MHC class I polypeptide-related sequence B 1.04757
TMCC3 transmembrane and coiled-coil domain family 3 1.04721
SYK spleen tyrosine kinase 1.04501
PDGFB platelet-derived growth factor beta polypeptide 1.04352
CCNA2 cyclin A2 1.04201
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.04126
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.04126
TACR1 tachykinin receptor 1 1.04126
PRKCG protein kinase C, gamma 1.04014
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.03976
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.03789
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.03789
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.03493
PKM pyruvate kinase, muscle 1.03382
CA2 carbonic anhydrase II 1.03382
ADRB3 adrenoceptor beta 3 1.03159
CAPN2 calpain 2, (m/II) large subunit 1.03159
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.03122
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.03122
DCT dopachrome tautomerase 1.03009
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.02971
ADRA1A adrenoceptor alpha 1A 1.02858
RHOA ras homolog family member A 1.02708
PTK2 protein tyrosine kinase 2 1.02708
THBS1 thrombospondin 1 1.02708
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.02522
CDK5 cyclin-dependent kinase 5 1.02522
GPNMB glycoprotein (transmembrane) nmb 1.02522
STAT5B signal transducer and activator of transcription 5B 1.02522
TXN thioredoxin 1.02522
KRT18 keratin 18, type I 1.02485
ADM adrenomedullin 1.02485
ANO3 anoctamin 3 1.02188
GDNF glial cell derived neurotrophic factor 1.02188
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.02188
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.02077
SCT secretin 1.02077
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.02077
TGFA transforming growth factor, alpha 1.0204
ZNF552 zinc finger protein 552 1.01928
DUSP6 dual specificity phosphatase 6 1.01814
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.01587
NBN nibrin 1.01587
FABP1 fatty acid binding protein 1, liver 1.01587
DPYSL2 dihydropyrimidinase-like 2 1.01587
BIRC2 baculoviral IAP repeat containing 2 1.01361
PKLR pyruvate kinase, liver and RBC 1.01286
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.01286
PER2 period circadian clock 2 1.01249
EIF4A2 eukaryotic translation initiation factor 4A2 1.01137
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.01137
DCXR dicarbonyl/L-xylulose reductase 1.01137
HMBS hydroxymethylbilane synthase 1.01137