Apoptosis Modulation and Signaling(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP1772_r84701
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Genes

80 proteins participating in the Apoptosis Modulation and Signaling(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
APAF1 apoptotic peptidase activating factor 1
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BLK BLK proto-oncogene, Src family tyrosine kinase
BMF Bcl2 modifying factor
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BOK BCL2-related ovarian killer
CAPNS1 calpain, small subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDKN2A cyclin-dependent kinase inhibitor 2A
CFLAR CASP8 and FADD-like apoptosis regulator
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CYCS cytochrome c, somatic
DAXX death-domain associated protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIABLO diablo, IAP-binding mitochondrial protein
ENDOG endonuclease G
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FOS FBJ murine osteosarcoma viral oncogene homolog
HN1 hematological and neurological expressed 1
HRK harakiri, BCL2 interacting protein
HTRA2 HtrA serine peptidase 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IRAK1 interleukin-1 receptor-associated kinase 1
JUN jun proto-oncogene
MADD MAP-kinase activating death domain
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MIR3190 microRNA 3190
MIR3191 microRNA 3191
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTRH2 peptidyl-tRNA hydrolase 2
SEPT4 septin 4
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOLLIP toll interacting protein
TRADD TNFRSF1A-associated via death domain
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase