Amphetamine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An amphetamine, the parent of the class of amphetamines, having the structure 1-phenylpropan-2-amine. It exists as a racemate. (Chemical Entities of Biological Interest Ontology, CHEBI_2679)
External Link http://ctdbase.org/detail.go?type=chem&acc=D000661
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Genes

104 genes/proteins interacting with the chemical Amphetamine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ADORA2A adenosine A2a receptor
ADRA1D adrenoceptor alpha 1D
ADRA2C adrenoceptor alpha 2C
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA7 annexin A7
ARC activity-regulated cytoskeleton-associated protein
ASIC1 acid sensing (proton gated) ion channel 1
ASIC2 acid sensing (proton gated) ion channel 2
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALB2 calbindin 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCKBR cholecystokinin B receptor
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CHRM1 cholinergic receptor, muscarinic 1
CHRM5 cholinergic receptor, muscarinic 5
CKB creatine kinase, brain
COMT catechol-O-methyltransferase
COPS5 COP9 signalosome subunit 5
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRH corticotropin releasing hormone
CRHR2 corticotropin releasing hormone receptor 2
CSNK1E casein kinase 1, epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DBN1 drebrin 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
DUSP1 dual specificity phosphatase 1
ELK1 ELK1, member of ETS oncogene family
ENO2 enolase 2 (gamma, neuronal)
ERP29 endoplasmic reticulum protein 29
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FGF2 fibroblast growth factor 2 (basic)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM5 glutamate receptor, metabotropic 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HCRTR1 hypocretin (orexin) receptor 1
HDAC1 histone deacetylase 1
HINT1 histidine triad nucleotide binding protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MDK midkine (neurite growth-promoting factor 2)
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NPY neuropeptide Y
NR1I2 nuclear receptor subfamily 1, group I, member 2
NTF3 neurotrophin 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCA protein kinase C, alpha
PTN pleiotrophin
PVALB parvalbumin
RAN RAN, member RAS oncogene family
RGS9 regulator of G-protein signaling 9
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SOD1 superoxide dismutase 1, soluble
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TH tyrosine hydroxylase
TNF tumor necrosis factor
TREX1 three prime repair exonuclease 1