Alzheimer's disease Gene Set

Dataset PhosphoSitePlus Phosphosite-Disease Associations
Category disease or phenotype associations
Type disease
Description A tauopathy that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. (Human Disease Ontology, DOID_10652)
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17 proteins associated with the disease Alzheimer's disease from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset.

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
DNM1L dynamin 1-like
DPYSL2 dihydropyrimidinase-like 2
GSK3B glycogen synthase kinase 3 beta
MAP1B microtubule-associated protein 1B
MAP2 microtubule-associated protein 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPT microtubule-associated protein tau
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SQSTM1 sequestosome 1