Alzheimer's Disease_CNS - Brain - Hippocampus (MMHCC)_GSE1297 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1297
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Genes

600 genes differentially expressed during Alzheimer's Disease_CNS - Brain - Hippocampus (MMHCC)_GSE1297 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
GRSF1 G-rich RNA sequence binding factor 1 3.08831
MTDH metadherin 2.91436
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.71969
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.6956
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 2.63077
MFAP1 microfibrillar-associated protein 1 2.61645
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.59424
ASB1 ankyrin repeat and SOCS box containing 1 2.54921
MCM9 minichromosome maintenance complex component 9 2.5359
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 2.53351
SLC35F2 solute carrier family 35, member F2 2.48578
GAPVD1 GTPase activating protein and VPS9 domains 1 2.46112
CTNNBL1 catenin, beta like 1 2.42747
UBE2D2 ubiquitin-conjugating enzyme E2D 2 2.42722
PNPO pyridoxamine 5'-phosphate oxidase 2.4228
COMMD9 COMM domain containing 9 2.37773
LUC7L2 LUC7-like 2 (S. cerevisiae) 2.3717
BGN biglycan 2.37168
ZNF43 zinc finger protein 43 2.35214
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.34213
OSBPL2 oxysterol binding protein-like 2 2.33858
C11ORF68 chromosome 11 open reading frame 68 2.33776
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.32213
SF3A1 splicing factor 3a, subunit 1, 120kDa 2.31402
CRTAP cartilage associated protein 2.30457
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 2.29673
GOLGB1 golgin B1 2.25402
SYF2 SYF2 pre-mRNA-splicing factor 2.24395
WDR74 WD repeat domain 74 2.20981
TARDBP TAR DNA binding protein 2.20026
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.18664
CTBP1 C-terminal binding protein 1 2.16961
ERF Ets2 repressor factor 2.15738
DBR1 debranching RNA lariats 1 2.15365
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.13065
PMS2P2 postmeiotic segregation increased 2 pseudogene 2 2.12585
NUP107 nucleoporin 107kDa 2.10784
GOLGA5 golgin A5 2.10617
GPR107 G protein-coupled receptor 107 2.07767
BTG3 BTG family, member 3 2.0713
MPI mannose phosphate isomerase 2.06999
DENND4C DENN/MADD domain containing 4C 2.05222
PINK1 PTEN induced putative kinase 1 2.05015
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.04772
PHKB phosphorylase kinase, beta 2.04086
USP19 ubiquitin specific peptidase 19 2.04063
ZNF24 zinc finger protein 24 2.03494
RPS20 ribosomal protein S20 2.03299
UBE3C ubiquitin protein ligase E3C 2.01608
ZNF778 zinc finger protein 778 2.00231
TRIM44 tripartite motif containing 44 1.98934
PDE8A phosphodiesterase 8A 1.98705
MTF2 metal response element binding transcription factor 2 1.96614
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.9598
LIN7C lin-7 homolog C (C. elegans) 1.95858
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 1.95386
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.9456
STS steroid sulfatase (microsomal), isozyme S 1.94335
BCKDK branched chain ketoacid dehydrogenase kinase 1.94075
LYRM1 LYR motif containing 1 1.93168
DPF3 D4, zinc and double PHD fingers, family 3 1.93144
PABPC1 poly(A) binding protein, cytoplasmic 1 1.92239
ZNF267 zinc finger protein 267 1.92164
ZFAND3 zinc finger, AN1-type domain 3 1.92108
NOVA1 neuro-oncological ventral antigen 1 1.91606
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 1.90832
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.90492
PLEKHO2 pleckstrin homology domain containing, family O member 2 1.90448
C14ORF169 chromosome 14 open reading frame 169 1.89916
TLK2 tousled-like kinase 2 1.89457
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 1.89377
TBL1X transducin (beta)-like 1X-linked 1.88919
ZDHHC17 zinc finger, DHHC-type containing 17 1.88513
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.88312
COPS7B COP9 signalosome subunit 7B 1.87595
SCML2 sex comb on midleg-like 2 (Drosophila) 1.87382
DFNA5 deafness, autosomal dominant 5 1.86116
TNIP1 TNFAIP3 interacting protein 1 1.85872
USP48 ubiquitin specific peptidase 48 1.85428
DUSP7 dual specificity phosphatase 7 1.84206
KCTD5 potassium channel tetramerization domain containing 5 1.84097
RAD54L2 RAD54-like 2 (S. cerevisiae) 1.83685
SEC63 SEC63 homolog (S. cerevisiae) 1.83474
AQR aquarius intron-binding spliceosomal factor 1.833
RUVBL1 RuvB-like AAA ATPase 1 1.83271
RHOQ ras homolog family member Q 1.83089
PDCD6 programmed cell death 6 1.82464
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.82309
MBD1 methyl-CpG binding domain protein 1 1.81825
CKAP2 cytoskeleton associated protein 2 1.80953
DPP8 dipeptidyl-peptidase 8 1.80756
MTFR1 mitochondrial fission regulator 1 1.80238
PCGF3 polycomb group ring finger 3 1.80191
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.79953
KLK2 kallikrein-related peptidase 2 1.79225
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.78955
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.78885
AGTR1 angiotensin II receptor, type 1 1.78765
PTAFR platelet-activating factor receptor 1.78348
SFXN3 sideroflexin 3 1.78197
CREBBP CREB binding protein 1.77247
TK2 thymidine kinase 2, mitochondrial 1.77133
PTBP2 polypyrimidine tract binding protein 2 1.76824
NUP98 nucleoporin 98kDa 1.76777
SFXN1 sideroflexin 1 1.76661
RECK reversion-inducing-cysteine-rich protein with kazal motifs 1.76211
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1.76056
CFHR2 complement factor H-related 2 1.75759
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.75639
SIK3 SIK family kinase 3 1.75374
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.75097
RPS10 ribosomal protein S10 1.75051
LRRC8D leucine rich repeat containing 8 family, member D 1.74827
TTC28 tetratricopeptide repeat domain 28 1.7475
COPZ1 coatomer protein complex, subunit zeta 1 1.74656
C1ORF116 chromosome 1 open reading frame 116 1.74311
LARP1 La ribonucleoprotein domain family, member 1 1.73862
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.73849
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 1.73472
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 1.7335
ZNF140 zinc finger protein 140 1.73174
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.72563
CCL23 chemokine (C-C motif) ligand 23 1.72507
EP300 E1A binding protein p300 1.7248
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 1.72456
VCL vinculin 1.72146
ZC3H3 zinc finger CCCH-type containing 3 1.72063
MET MET proto-oncogene, receptor tyrosine kinase 1.7195
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 1.71708
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.71669
DTX3 deltex 3, E3 ubiquitin ligase 1.71581
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.70925
ZNHIT6 zinc finger, HIT-type containing 6 1.70632
ADNP2 ADNP homeobox 2 1.70482
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.69889
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.69551
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.69433
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.69201
QRICH1 glutamine-rich 1 1.69186
NCOA2 nuclear receptor coactivator 2 1.68285
MANSC1 MANSC domain containing 1 1.68144
TMED3 transmembrane emp24 protein transport domain containing 3 1.6803
ZNF250 zinc finger protein 250 1.67779
PLXNB2 plexin B2 1.67458
ZFHX3 zinc finger homeobox 3 1.67254
DUSP10 dual specificity phosphatase 10 1.67233
TUBA3C tubulin, alpha 3c 1.67125
FLAD1 flavin adenine dinucleotide synthetase 1 1.67048
NID1 nidogen 1 1.67039
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 1.66832
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.66371
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 1.66139
UBB ubiquitin B 1.65952
PCGF2 polycomb group ring finger 2 1.6529
MKNK1 MAP kinase interacting serine/threonine kinase 1 1.65282
MT1G metallothionein 1G 1.65267
ZMYM1 zinc finger, MYM-type 1 1.65209
RANBP3 RAN binding protein 3 1.64567
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.64544
ALG9 ALG9, alpha-1,2-mannosyltransferase 1.6436
FBXL5 F-box and leucine-rich repeat protein 5 1.6424
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.64155
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.63588
TOR3A torsin family 3, member A 1.63197
ELOVL5 ELOVL fatty acid elongase 5 1.62893
DIABLO diablo, IAP-binding mitochondrial protein 1.62861
PDLIM7 PDZ and LIM domain 7 (enigma) 1.62611
CLUAP1 clusterin associated protein 1 1.62584
ADD1 adducin 1 (alpha) 1.6252
TEX10 testis expressed 10 1.62098
PXDC1 PX domain containing 1 1.61941
RWDD3 RWD domain containing 3 1.61124
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 1.61081
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.61068
PPA2 pyrophosphatase (inorganic) 2 1.60801
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.60773
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.60547
ZNF91 zinc finger protein 91 1.60226
CLOCK clock circadian regulator 1.5977
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.59699
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.59622
RABL3 RAB, member of RAS oncogene family-like 3 1.59582
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 1.58914
KDM5B lysine (K)-specific demethylase 5B 1.58899
USP1 ubiquitin specific peptidase 1 1.58756
KCTD9 potassium channel tetramerization domain containing 9 1.58673
DET1 de-etiolated homolog 1 (Arabidopsis) 1.58586
CCDC51 coiled-coil domain containing 51 1.57034
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.57016
TMEM11 transmembrane protein 11 1.56968
PIGR polymeric immunoglobulin receptor 1.5694
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.56848
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.5667
KIF2A kinesin heavy chain member 2A 1.56545
COMMD4 COMM domain containing 4 1.56495
CCDC59 coiled-coil domain containing 59 1.56191
HDDC2 HD domain containing 2 1.5606
ZSWIM1 zinc finger, SWIM-type containing 1 1.5566
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.55396
PLD2 phospholipase D2 1.55261
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 1.55255
IL10RA interleukin 10 receptor, alpha 1.55225
TNRC6B trinucleotide repeat containing 6B 1.55046
DMTF1 cyclin D binding myb-like transcription factor 1 1.54693
ZNF350 zinc finger protein 350 1.54673
C8ORF33 chromosome 8 open reading frame 33 1.54673
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.54375
NXT2 nuclear transport factor 2-like export factor 2 1.54143
IQCK IQ motif containing K 1.53996
NBAS neuroblastoma amplified sequence 1.53876
NLE1 notchless homolog 1 (Drosophila) 1.53855
SPG11 spastic paraplegia 11 (autosomal recessive) 1.536
GIPC1 GIPC PDZ domain containing family, member 1 1.53514
ZNF281 zinc finger protein 281 1.53455
HMGXB3 HMG box domain containing 3 1.53338
GOLGA4 golgin A4 1.53272
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 1.52999
ZNF253 zinc finger protein 253 1.52872
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.52567
SAE1 SUMO1 activating enzyme subunit 1 1.52559
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.52449
SEPT6 septin 6 1.52303
KIAA0907 KIAA0907 1.52127
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 1.52055
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 1.51991
PTCRA pre T-cell antigen receptor alpha 1.51303
FKBP9 FK506 binding protein 9, 63 kDa 1.51243
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.50965
ARL5A ADP-ribosylation factor-like 5A 1.50945
ZDHHC3 zinc finger, DHHC-type containing 3 1.50817
LUZP1 leucine zipper protein 1 1.50779
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.50719
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1.49895
TGFBR3 transforming growth factor, beta receptor III 1.49568
FTO fat mass and obesity associated 1.49561
CDK13 cyclin-dependent kinase 13 1.49214
IFT122 intraflagellar transport 122 1.49164
ZNF473 zinc finger protein 473 1.49078
PDS5B PDS5 cohesin associated factor B 1.48986
DRG1 developmentally regulated GTP binding protein 1 1.48868
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 1.48694
ZNF280A zinc finger protein 280A 1.48639
PRPF3 pre-mRNA processing factor 3 1.48404
MT1X metallothionein 1X 1.48312
FBXL7 F-box and leucine-rich repeat protein 7 1.48141
LTK leukocyte receptor tyrosine kinase 1.47695
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 1.47638
MT1H metallothionein 1H 1.47531
TTC17 tetratricopeptide repeat domain 17 1.47524
HAX1 HCLS1 associated protein X-1 1.47455
ATP10A ATPase, class V, type 10A 1.47346
C11ORF48 1.47261
ZNF136 zinc finger protein 136 1.47111
TRIT1 tRNA isopentenyltransferase 1 1.47081
CXCL5 chemokine (C-X-C motif) ligand 5 1.47036
AMT aminomethyltransferase 1.46979
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.46881
FRG1 FSHD region gene 1 1.46743
RCL1 RNA terminal phosphate cyclase-like 1 1.46724
RABGAP1 RAB GTPase activating protein 1 1.46597
UBE3B ubiquitin protein ligase E3B 1.46509
MTRF1L mitochondrial translational release factor 1-like 1.46407
TRIM33 tripartite motif containing 33 1.46298
MRS2 MRS2 magnesium transporter 1.46183
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.46015
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 1.45847
TRMT61B tRNA methyltransferase 61B 1.45843
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.45783
FZD5 frizzled class receptor 5 1.45636
DERA deoxyribose-phosphate aldolase (putative) 1.45589
ANGEL2 angel homolog 2 (Drosophila) 1.45436
TNIK TRAF2 and NCK interacting kinase 1.4532
MAN2A2 mannosidase, alpha, class 2A, member 2 1.45262
FRY furry homolog (Drosophila) 1.4504
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 1.45038
ZNF3 zinc finger protein 3 1.45018
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.44903
GCDH glutaryl-CoA dehydrogenase 1.44557
GPHN gephyrin 1.44278
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.44243
CMKLR1 chemerin chemokine-like receptor 1 1.44225
ZFAND6 zinc finger, AN1-type domain 6 1.44137
CLDN11 claudin 11 1.44097
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.4376
VRK3 vaccinia related kinase 3 1.43666
TPMT thiopurine S-methyltransferase 1.43608
RMI1 RecQ mediated genome instability 1 1.43597
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 1.4359
PTPRB protein tyrosine phosphatase, receptor type, B 1.43229
HPS4 Hermansky-Pudlak syndrome 4 1.43131
NAV3 neuron navigator 3 1.43059
RABGAP1L RAB GTPase activating protein 1-like 1.43003
PTPRF protein tyrosine phosphatase, receptor type, F 1.42926
PDZD3 PDZ domain containing 3 1.42667
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.42523
ZNF702P zinc finger protein 702, pseudogene 1.4248
LSG1 large 60S subunit nuclear export GTPase 1 1.42467
ZNF12 zinc finger protein 12 1.42339
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.42335
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.42107

decreased expression

Symbol Name Standardized Value
ICT1 immature colon carcinoma transcript 1 -2.97823
GNPAT glyceronephosphate O-acyltransferase -2.66089
TUBG2 tubulin, gamma 2 -2.60665
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -2.53666
FASTKD3 FAST kinase domains 3 -2.53191
COQ9 coenzyme Q9 -2.5129
PNN pinin, desmosome associated protein -2.50959
DIEXF digestive organ expansion factor homolog (zebrafish) -2.50599
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.472
GOLGA1 golgin A1 -2.46213
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.38416
BCL2L2 BCL2-like 2 -2.34979
CSNK1G3 casein kinase 1, gamma 3 -2.34236
MAK16 MAK16 homolog (S. cerevisiae) -2.32839
CLCN6 chloride channel, voltage-sensitive 6 -2.30286
TUBGCP4 tubulin, gamma complex associated protein 4 -2.29296
ZMYM4 zinc finger, MYM-type 4 -2.27154
MAPK14 mitogen-activated protein kinase 14 -2.25819
SEC23B Sec23 homolog B (S. cerevisiae) -2.24949
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.24071
GCAT glycine C-acetyltransferase -2.23768
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.22852
WFDC1 WAP four-disulfide core domain 1 -2.20719
PUM1 pumilio RNA-binding family member 1 -2.1854
MRPS16 mitochondrial ribosomal protein S16 -2.18406
RB1CC1 RB1-inducible coiled-coil 1 -2.18014
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.15064
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -2.14139
CCNL1 cyclin L1 -2.13635
KALRN kalirin, RhoGEF kinase -2.12012
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -2.11854
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.11743
SF3B5 splicing factor 3b, subunit 5, 10kDa -2.11554
CTSB cathepsin B -2.1032
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) -2.10215
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -2.0858
ACAD8 acyl-CoA dehydrogenase family, member 8 -2.05765
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -2.05592
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.04152
ECH1 enoyl CoA hydratase 1, peroxisomal -2.03665
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.03472
EPS15 epidermal growth factor receptor pathway substrate 15 -2.02889
CDH10 cadherin 10, type 2 (T2-cadherin) -2.02816
SERBP1 SERPINE1 mRNA binding protein 1 -1.99359
FAM127B family with sequence similarity 127, member B -1.9838
IMMT inner membrane protein, mitochondrial -1.96853
PANK3 pantothenate kinase 3 -1.96835
TM9SF4 transmembrane 9 superfamily protein member 4 -1.96485
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.95808
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -1.95437
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.94979
SCAPER S-phase cyclin A-associated protein in the ER -1.94058
NPHP4 nephronophthisis 4 -1.93304
HARS2 histidyl-tRNA synthetase 2, mitochondrial -1.92771
ACO2 aconitase 2, mitochondrial -1.92144
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.9137
YLPM1 YLP motif containing 1 -1.91338
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -1.91065
WDFY3 WD repeat and FYVE domain containing 3 -1.89092
UBP1 upstream binding protein 1 (LBP-1a) -1.88892
CLIP3 CAP-GLY domain containing linker protein 3 -1.88066
ATG5 autophagy related 5 -1.87739
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.86889
GTDC1 glycosyltransferase-like domain containing 1 -1.86771
TLE2 transducin-like enhancer of split 2 -1.8643
TTC37 tetratricopeptide repeat domain 37 -1.85782
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -1.85741
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -1.84351
TRAK1 trafficking protein, kinesin binding 1 -1.83921
COG5 component of oligomeric golgi complex 5 -1.83867
FUS FUS RNA binding protein -1.82932
TPI1 triosephosphate isomerase 1 -1.82866
GLI3 GLI family zinc finger 3 -1.81939
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.81371
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -1.8136
LARP4B La ribonucleoprotein domain family, member 4B -1.81062
TXNL1 thioredoxin-like 1 -1.80199
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -1.80145
HYPK huntingtin interacting protein K -1.78991
FLOT1 flotillin 1 -1.78541
TOX3 TOX high mobility group box family member 3 -1.782
DEAF1 DEAF1 transcription factor -1.77721
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.77424
CYLD cylindromatosis (turban tumor syndrome) -1.77371
STX1A syntaxin 1A (brain) -1.77334
KIAA0232 KIAA0232 -1.76987
WDR19 WD repeat domain 19 -1.76973
EFTUD1 elongation factor Tu GTP binding domain containing 1 -1.75898
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.75647
THUMPD2 THUMP domain containing 2 -1.75425
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 -1.75407
ETHE1 ethylmalonic encephalopathy 1 -1.75388
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.74844
COL4A1 collagen, type IV, alpha 1 -1.74801
NEK4 NIMA-related kinase 4 -1.74427
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -1.74131
PRPF19 pre-mRNA processing factor 19 -1.72706
GPX4 glutathione peroxidase 4 -1.72666
YIPF1 Yip1 domain family, member 1 -1.72665
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.7243
CRELD1 cysteine-rich with EGF-like domains 1 -1.7241
MAGED2 melanoma antigen family D2 -1.72333
ERLIN1 ER lipid raft associated 1 -1.72181
HTRA1 HtrA serine peptidase 1 -1.72107
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -1.71865
KIAA0753 KIAA0753 -1.71634
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.71604
SRSF4 serine/arginine-rich splicing factor 4 -1.71501
SRSF7 serine/arginine-rich splicing factor 7 -1.71428
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -1.70647
ZDHHC13 zinc finger, DHHC-type containing 13 -1.69653
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) -1.69602
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.69375
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.6904
PCM1 pericentriolar material 1 -1.68079
KLHL3 kelch-like family member 3 -1.68003
MRPL15 mitochondrial ribosomal protein L15 -1.67867
DDB1 damage-specific DNA binding protein 1, 127kDa -1.67823
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -1.67546
TTLL12 tubulin tyrosine ligase-like family member 12 -1.66281
APOOL apolipoprotein O-like -1.66279
ATXN7L3B ataxin 7-like 3B -1.6591
C9ORF78 chromosome 9 open reading frame 78 -1.65815
ATF4 activating transcription factor 4 -1.6552
CFB complement factor B -1.64696
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.64612
CLINT1 clathrin interactor 1 -1.64208
TCF4 transcription factor 4 -1.64163
DNM1L dynamin 1-like -1.64068
LRRC59 leucine rich repeat containing 59 -1.63488
TSEN34 TSEN34 tRNA splicing endonuclease subunit -1.63024
RLF rearranged L-myc fusion -1.62794
HEATR1 HEAT repeat containing 1 -1.62723
MFSD5 major facilitator superfamily domain containing 5 -1.62713
NME6 NME/NM23 nucleoside diphosphate kinase 6 -1.6261
RANBP2 RAN binding protein 2 -1.6258
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.62157
FAM162A family with sequence similarity 162, member A -1.61905
VAV3 vav 3 guanine nucleotide exchange factor -1.61094
TOR1B torsin family 1, member B (torsin B) -1.60755
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -1.60732
SUMO2 small ubiquitin-like modifier 2 -1.60687
UPP1 uridine phosphorylase 1 -1.6062
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -1.60603
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.6056
NME2 NME/NM23 nucleoside diphosphate kinase 2 -1.60233
KIAA0100 KIAA0100 -1.60232
ARL1 ADP-ribosylation factor-like 1 -1.60086
ASCC3 activating signal cointegrator 1 complex subunit 3 -1.5945
GCH1 GTP cyclohydrolase 1 -1.59316
TMEM97 transmembrane protein 97 -1.59111
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -1.59065
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -1.58808
RFXAP regulatory factor X-associated protein -1.58478
WDR12 WD repeat domain 12 -1.57772
CHRDL1 chordin-like 1 -1.57337
TM9SF1 transmembrane 9 superfamily member 1 -1.57324
RBMX2 RNA binding motif protein, X-linked 2 -1.57046
CCNG2 cyclin G2 -1.56974
R3HDM2 R3H domain containing 2 -1.56493
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -1.56354
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -1.55911
ANKRD6 ankyrin repeat domain 6 -1.5581
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.55445
SEC31A SEC31 homolog A (S. cerevisiae) -1.55261
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -1.54536
GRIP2 glutamate receptor interacting protein 2 -1.54213
FOXJ3 forkhead box J3 -1.53937
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -1.53937
FRG1B FSHD region gene 1 family, member B -1.53294
LRRC41 leucine rich repeat containing 41 -1.52352
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.52113
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) -1.51982
KIAA0319 KIAA0319 -1.51862
SYNJ1 synaptojanin 1 -1.5185
XKR8 XK, Kell blood group complex subunit-related family, member 8 -1.51836
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -1.51453
KPNA1 karyopherin alpha 1 (importin alpha 5) -1.51322
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -1.51245
RGS20 regulator of G-protein signaling 20 -1.51171
GNAS GNAS complex locus -1.51013
CCNA1 cyclin A1 -1.50751
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -1.50643
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 -1.5059
PRDM10 PR domain containing 10 -1.5059
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -1.50414
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.50114
ABAT 4-aminobutyrate aminotransferase -1.50104
PRPH2 peripherin 2 (retinal degeneration, slow) -1.49993
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -1.49869
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) -1.49738
INTS6 integrator complex subunit 6 -1.49532
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -1.4947
RPL7A ribosomal protein L7a -1.49436
FASTKD5 FAST kinase domains 5 -1.49415
KIAA0368 KIAA0368 -1.49388
MIA3 melanoma inhibitory activity family, member 3 -1.49362
MUS81 MUS81 structure-specific endonuclease subunit -1.4921
CA7 carbonic anhydrase VII -1.49129
TTK TTK protein kinase -1.49015
CBX3 chromobox homolog 3 -1.48858
PUS1 pseudouridylate synthase 1 -1.48752
PDC phosducin -1.48748
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.48455
KIAA1407 KIAA1407 -1.48252
SH2B1 SH2B adaptor protein 1 -1.47368
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -1.4736
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -1.46981
DUSP6 dual specificity phosphatase 6 -1.46655
EXTL3 exostosin-like glycosyltransferase 3 -1.46574
TMEM242 transmembrane protein 242 -1.46338
SNX13 sorting nexin 13 -1.46118
RGS17 regulator of G-protein signaling 17 -1.45996
MCM3AP minichromosome maintenance complex component 3 associated protein -1.45583
UFM1 ubiquitin-fold modifier 1 -1.45551
TGDS TDP-glucose 4,6-dehydratase -1.45445
YTHDC2 YTH domain containing 2 -1.45049
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -1.44588
FSCN1 fascin actin-bundling protein 1 -1.44269
RAB21 RAB21, member RAS oncogene family -1.44158
TSPAN14 tetraspanin 14 -1.44139
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -1.44105
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -1.43957
NOL11 nucleolar protein 11 -1.43954
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) -1.43653
LOC257152 uncharacterized LOC257152 -1.43478
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -1.43083
SLC25A38 solute carrier family 25, member 38 -1.43052
BOP1 block of proliferation 1 -1.43017
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -1.42859
CINP cyclin-dependent kinase 2 interacting protein -1.42456
ZFP64 ZFP64 zinc finger protein -1.42153
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -1.42085
KLK10 kallikrein-related peptidase 10 -1.41938
NUPL1 nucleoporin like 1 -1.41826
GLRX3 glutaredoxin 3 -1.41778
GPN2 GPN-loop GTPase 2 -1.41585
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -1.41013
TRAF5 TNF receptor-associated factor 5 -1.40905
ECD ecdysoneless homolog (Drosophila) -1.40717
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -1.40707
THOC2 THO complex 2 -1.40621
RPP30 ribonuclease P/MRP 30kDa subunit -1.40151
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -1.40151
PRR4 proline rich 4 (lacrimal) -1.40126
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -1.40045
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -1.40038
KLHL32 kelch-like family member 32 -1.3986
RPL32 ribosomal protein L32 -1.39781
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -1.39603
PLXNA2 plexin A2 -1.39519
STK24 serine/threonine kinase 24 -1.39452
USP46 ubiquitin specific peptidase 46 -1.39012
CLK4 CDC-like kinase 4 -1.38995
ACYP2 acylphosphatase 2, muscle type -1.38958
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -1.38836
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) -1.3879
LHX3 LIM homeobox 3 -1.38771
TBCA tubulin folding cofactor A -1.38298
TMEM176A transmembrane protein 176A -1.38233
AARS alanyl-tRNA synthetase -1.38213
KRT83 keratin 83, type II -1.38198
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -1.38189
COPA coatomer protein complex, subunit alpha -1.37967
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -1.37963
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -1.37639
HDAC6 histone deacetylase 6 -1.37518
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.37345
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -1.37093
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -1.3673
RHOBTB1 Rho-related BTB domain containing 1 -1.36672
TBK1 TANK-binding kinase 1 -1.36519
PPP1R16B protein phosphatase 1, regulatory subunit 16B -1.36495
PVRL3 poliovirus receptor-related 3 -1.36409
C1ORF95 chromosome 1 open reading frame 95 -1.36128
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.35996
WDTC1 WD and tetratricopeptide repeats 1 -1.35984
KLHL22 kelch-like family member 22 -1.35908
PTOV1 prostate tumor overexpressed 1 -1.35848
NKAIN1 Na+/K+ transporting ATPase interacting 1 -1.35716
DMD dystrophin -1.35386
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -1.35226
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.35151
CDCA8 cell division cycle associated 8 -1.35092
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -1.34665
CAPRIN2 caprin family member 2 -1.34541
ANK1 ankyrin 1, erythrocytic -1.34469
E2F5 E2F transcription factor 5, p130-binding -1.34469
METAP1 methionyl aminopeptidase 1 -1.34403
R3HDM1 R3H domain containing 1 -1.34163
POU6F1 POU class 6 homeobox 1 -1.34149
RGS19 regulator of G-protein signaling 19 -1.34023
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F -1.34004
ADORA2B adenosine A2b receptor -1.33799
TBPL1 TBP-like 1 -1.33636
RBFA ribosome binding factor A (putative) -1.33599
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like -1.33556
NCLN nicalin -1.33496
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -1.33299
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.33269