Acidosis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Abnormal acid accumulation or depletion of base. (Human Phenotype Ontology, HP_0001941)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D000138
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Genes

643 genes/proteins associated with the disease Acidosis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 2.88009
IL6 interleukin 6 2.34419
TNF tumor necrosis factor 2.32669
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.28683
IL1B interleukin 1, beta 2.27302
CAT catalase 2.1452
FOS FBJ murine osteosarcoma viral oncogene homolog 2.08573
REN renin 2.06076
BCL2 B-cell CLL/lymphoma 2 2.00731
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.98553
HMOX1 heme oxygenase 1 1.97813
MAPK3 mitogen-activated protein kinase 3 1.96343
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.94965
CALCA calcitonin-related polypeptide alpha 1.91716
NOS2 nitric oxide synthase 2, inducible 1.91317
MAPK1 mitogen-activated protein kinase 1 1.90442
VEGFA vascular endothelial growth factor A 1.89894
JUN jun proto-oncogene 1.89829
MPO myeloperoxidase 1.89439
CCL2 chemokine (C-C motif) ligand 2 1.88192
ICAM1 intercellular adhesion molecule 1 1.86219
TAC1 tachykinin, precursor 1 1.85922
IFNG interferon, gamma 1.85695
CD36 CD36 molecule (thrombospondin receptor) 1.82673
CXCL8 chemokine (C-X-C motif) ligand 8 1.81903
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.79025
LPL lipoprotein lipase 1.78511
ALB albumin 1.76424
PARP1 poly (ADP-ribose) polymerase 1 1.76131
DDIT3 DNA-damage-inducible transcript 3 1.75082
TGFB1 transforming growth factor, beta 1 1.74661
BAX BCL2-associated X protein 1.7422
IL10 interleukin 10 1.74059
CA2 carbonic anhydrase II 1.71441
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.71276
HSPA1A heat shock 70kDa protein 1A 1.70491
CXCL2 chemokine (C-X-C motif) ligand 2 1.70182
ADRB2 adrenoceptor beta 2, surface 1.69513
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.67611
DRD1 dopamine receptor D1 1.67462
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.67289
G6PD glucose-6-phosphate dehydrogenase 1.65864
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.65136
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.64708
CPT1A carnitine palmitoyltransferase 1A (liver) 1.64708
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.64101
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.6381
EGR1 early growth response 1 1.63005
TP53 tumor protein p53 1.63005
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.62915
FAS Fas cell surface death receptor 1.62803
LEP leptin 1.62335
EDN1 endothelin 1 1.61389
PPARG peroxisome proliferator-activated receptor gamma 1.61084
ADRB1 adrenoceptor beta 1 1.61061
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.60407
GADD45A growth arrest and DNA-damage-inducible, alpha 1.59989
CCL3 chemokine (C-C motif) ligand 3 1.59778
HSF1 heat shock transcription factor 1 1.59755
PPARA peroxisome proliferator-activated receptor alpha 1.59451
GSTP1 glutathione S-transferase pi 1 1.59148
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.58818
NPY neuropeptide Y 1.58232
NOS3 nitric oxide synthase 3 (endothelial cell) 1.58018
NUPR1 nuclear protein, transcriptional regulator, 1 1.56875
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.56681
CLU clusterin 1.55797
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.5501
SREBF1 sterol regulatory element binding transcription factor 1 1.54912
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.54208
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.53941
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.53892
DUSP1 dual specificity phosphatase 1 1.53796
IL2 interleukin 2 1.53675
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.53332
TIMP1 TIMP metallopeptidase inhibitor 1 1.52889
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.52718
SOD1 superoxide dismutase 1, soluble 1.51961
PRKCE protein kinase C, epsilon 1.5181
PKLR pyruvate kinase, liver and RBC 1.5123
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.50398
PRL prolactin 1.50298
FABP1 fatty acid binding protein 1, liver 1.49915
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.49711
GSTT1 glutathione S-transferase theta 1 1.49122
NGF nerve growth factor (beta polypeptide) 1.48479
CCND1 cyclin D1 1.48299
FADS2 fatty acid desaturase 2 1.48196
HNF4A hepatocyte nuclear factor 4, alpha 1.4794
EDNRB endothelin receptor type B 1.47889
CTGF connective tissue growth factor 1.47864
SOD2 superoxide dismutase 2, mitochondrial 1.47736
CREM cAMP responsive element modulator 1.47686
FOXO1 forkhead box O1 1.47426
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.46832
MMP9 matrix metallopeptidase 9 1.46781
ENO3 enolase 3 (beta, muscle) 1.46754
APOE apolipoprotein E 1.46674
GCLC glutamate-cysteine ligase, catalytic subunit 1.46542
GPX1 glutathione peroxidase 1 1.46436
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.46041
CCND2 cyclin D2 1.45989
GSTM3 glutathione S-transferase mu 3 (brain) 1.45247
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.44872
NES nestin 1.44681
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.44653
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.44409
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.44327
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.44327
ODC1 ornithine decarboxylase 1 1.44193
SPP1 secreted phosphoprotein 1 1.43727
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.43347
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.43239
FASN fatty acid synthase 1.43048
LOX lysyl oxidase 1.42994
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.42913
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.42885
EFNA1 ephrin-A1 1.42696
POR P450 (cytochrome) oxidoreductase 1.42374
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.41748
ARC activity-regulated cytoskeleton-associated protein 1.41748
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.41451
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41202
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.41202
VEGFC vascular endothelial growth factor C 1.41146
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.40842
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.4065
FOSL2 FOS-like antigen 2 1.40541
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.40288
KDR kinase insert domain receptor 1.40176
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.40176
DRD2 dopamine receptor D2 1.3973
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.39563
HADH hydroxyacyl-CoA dehydrogenase 1.39366
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.3878
MAPK8 mitogen-activated protein kinase 8 1.38696
GAP43 growth associated protein 43 1.38498
ADK adenosine kinase 1.38441
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.38441
CFLAR CASP8 and FADD-like apoptosis regulator 1.38213
ADRA1B adrenoceptor alpha 1B 1.37676
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.37418
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.37246
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.37018
UBE2I ubiquitin-conjugating enzyme E2I 1.36848
GCK glucokinase (hexokinase 4) 1.36848
GDF15 growth differentiation factor 15 1.36706
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.36418
MAOA monoamine oxidase A 1.36218
INSIG2 insulin induced gene 2 1.36076
PDE4B phosphodiesterase 4B, cAMP-specific 1.36047
NEFH neurofilament, heavy polypeptide 1.36047
IL1A interleukin 1, alpha 1.35906
CNR1 cannabinoid receptor 1 (brain) 1.35647
CRYAB crystallin, alpha B 1.35473
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.35473
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.35299
GSK3B glycogen synthase kinase 3 beta 1.34811
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.34752
TRIB3 tribbles pseudokinase 3 1.34518
IGFBP1 insulin-like growth factor binding protein 1 1.34343
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.33995
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.33995
IGF1 insulin-like growth factor 1 (somatomedin C) 1.33966
ADIPOQ adiponectin, C1Q and collagen domain containing 1.33909
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.33761
MDH1 malate dehydrogenase 1, NAD (soluble) 1.33494
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.33494
AFMID arylformamidase 1.33434
SCARB1 scavenger receptor class B, member 1 1.33228
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.33199
PYGL phosphorylase, glycogen, liver 1.3314
OXT oxytocin/neurophysin I prepropeptide 1.33022
TAGLN transgelin 1.32756
TIMP2 TIMP metallopeptidase inhibitor 2 1.32696
TH tyrosine hydroxylase 1.32637
GNAS GNAS complex locus 1.32518
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.32518
VCL vinculin 1.32458
CTSL cathepsin L 1.3228
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.32251
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.31807
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.31807
HPS1 Hermansky-Pudlak syndrome 1 1.31536
GLS glutaminase 1.31446
EGFR epidermal growth factor receptor 1.31357
PRDX2 peroxiredoxin 2 1.31357
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.31208
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.31208
BID BH3 interacting domain death agonist 1.30881
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.30727
ACHE acetylcholinesterase (Yt blood group) 1.3036
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.30177
HBEGF heparin-binding EGF-like growth factor 1.29966
SDC4 syndecan 4 1.29812
VCAM1 vascular cell adhesion molecule 1 1.29781
ASL argininosuccinate lyase 1.29688
SDS serine dehydratase 1.29688
HDAC5 histone deacetylase 5 1.29688
AK3 adenylate kinase 3 1.29688
GSR glutathione reductase 1.29564
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.29471
RB1 retinoblastoma 1 1.29256
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.29225
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.29133
S100A8 S100 calcium binding protein A8 1.28641
LDLR low density lipoprotein receptor 1.28425
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.28425
ATF3 activating transcription factor 3 1.28364
ADRB3 adrenoceptor beta 3 1.28241
OTC ornithine carbamoyltransferase 1.28241
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.27936
PRKCA protein kinase C, alpha 1.27936
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.27782
NQO1 NAD(P)H dehydrogenase, quinone 1 1.27782
PCNA proliferating cell nuclear antigen 1.27595
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.27378
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.27347
PTK2B protein tyrosine kinase 2 beta 1.27347
GRB14 growth factor receptor-bound protein 14 1.27347
DUSP6 dual specificity phosphatase 6 1.27132
SOCS2 suppressor of cytokine signaling 2 1.27039
CCNG1 cyclin G1 1.26947
ILK integrin-linked kinase 1.26886
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.26825
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.26763
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.26638
GH1 growth hormone 1 1.26514
HSPA8 heat shock 70kDa protein 8 1.26514
VDAC1 voltage-dependent anion channel 1 1.26175
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.26175
JUNB jun B proto-oncogene 1.26052
PDLIM7 PDZ and LIM domain 7 (enigma) 1.26021
MAP2K6 mitogen-activated protein kinase kinase 6 1.25899
POMC proopiomelanocortin 1.25776
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.25745
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.25619
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.25619
JAK1 Janus kinase 1 1.25619
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.25619
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.25494
BCL2L1 BCL2-like 1 1.254
COL3A1 collagen, type III, alpha 1 1.25121
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.2509
ACO2 aconitase 2, mitochondrial 1.2509
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.2509
INSIG1 insulin induced gene 1 1.24935
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 1.24905
GJA1 gap junction protein, alpha 1, 43kDa 1.24874
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.24781
FGF2 fibroblast growth factor 2 (basic) 1.24433
MAP1B microtubule-associated protein 1B 1.2437
USP2 ubiquitin specific peptidase 2 1.2437
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.24275
THRSP thyroid hormone responsive 1.23993
NEFL neurofilament, light polypeptide 1.23743
AOC1 amine oxidase, copper containing 1 1.23584
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.23456
MMP13 matrix metallopeptidase 13 1.23392
GRIK5 glutamate receptor, ionotropic, kainate 5 1.23106
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 1.23106
ELOVL6 ELOVL fatty acid elongase 6 1.22948
LIF leukemia inhibitory factor 1.22948
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.2279
MAL mal, T-cell differentiation protein 1.2279
IL2RA interleukin 2 receptor, alpha 1.22696
STAR steroidogenic acute regulatory protein 1.22566
FOXA3 forkhead box A3 1.22469
LCN2 lipocalin 2 1.22469
ALDOA aldolase A, fructose-bisphosphate 1.22436
LEPR leptin receptor 1.22274
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.22274
ATF4 activating transcription factor 4 1.2208
AVPR1A arginine vasopressin receptor 1A 1.22048
B2M beta-2-microglobulin 1.21919
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.21919
UBTF upstream binding transcription factor, RNA polymerase I 1.21823
NFE2L2 nuclear factor, erythroid 2-like 2 1.21727
NRP1 neuropilin 1 1.21663
CAV1 caveolin 1, caveolae protein, 22kDa 1.21567
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.21435
MMP2 matrix metallopeptidase 2 1.21304
IL4 interleukin 4 1.21304
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.21304
HSPB1 heat shock 27kDa protein 1 1.21304
LIPE lipase, hormone-sensitive 1.21271
DDIT4 DNA-damage-inducible transcript 4 1.21011
FABP4 fatty acid binding protein 4, adipocyte 1.20816
TSC22D1 TSC22 domain family, member 1 1.2046
SQSTM1 sequestosome 1 1.20295
ACACB acetyl-CoA carboxylase beta 1.20196
BGLAP bone gamma-carboxyglutamate (gla) protein 1.20196
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.19966
TK1 thymidine kinase 1, soluble 1.19966
ALAS1 5'-aminolevulinate synthase 1 1.19966
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.1977
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.19737
COL1A1 collagen, type I, alpha 1 1.19607
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.19477
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.19279
BMP4 bone morphogenetic protein 4 1.19246
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.19246
ECI1 enoyl-CoA delta isomerase 1 1.19146
EGLN3 egl-9 family hypoxia-inducible factor 3 1.19146
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 1.18882
GTPBP2 GTP binding protein 2 1.18882
ACAT1 acetyl-CoA acetyltransferase 1 1.18783
SQLE squalene epoxidase 1.18783
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 1.18751
EGR2 early growth response 2 1.18554
AQP4 aquaporin 4 1.18489
NDRG2 NDRG family member 2 1.18456
GCLM glutamate-cysteine ligase, modifier subunit 1.18359
AACS acetoacetyl-CoA synthetase 1.18326
RAB4A RAB4A, member RAS oncogene family 1.18326
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.18326
GADD45G growth arrest and DNA-damage-inducible, gamma 1.18326
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.18326
TXNRD1 thioredoxin reductase 1 1.18226
G6PC glucose-6-phosphatase, catalytic subunit 1.18093
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.17926
CYCS cytochrome c, somatic 1.17926
CDK2 cyclin-dependent kinase 2 1.1786
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.17794
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.17794
PFN1 profilin 1 1.17794
MT1A metallothionein 1A 1.17761
FOLR1 folate receptor 1 (adult) 1.17464
SPTBN1 spectrin, beta, non-erythrocytic 1 1.17464
PER1 period circadian clock 1 1.17464
IL12B interleukin 12B 1.17464
IGFBP3 insulin-like growth factor binding protein 3 1.17431
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.17366
FN1 fibronectin 1 1.17366
SARDH sarcosine dehydrogenase 1.17268
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.17168
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.17
EIF5 eukaryotic translation initiation factor 5 1.16833
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.16833
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.16833
CALR calreticulin 1.16766
SLC26A5 solute carrier family 26 (anion exchanger), member 5 1.16733
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.16567
ERRFI1 ERBB receptor feedback inhibitor 1 1.165
RGN regucalcin 1.165
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.16335
RGS2 regulator of G-protein signaling 2 1.16335
NEFM neurofilament, medium polypeptide 1.16203
HDC histidine decarboxylase 1.16203
GLUL glutamate-ammonia ligase 1.16137
PRKCB protein kinase C, beta 1.15933
PENK proenkephalin 1.15933
MFSD10 major facilitator superfamily domain containing 10 1.15763
SYT13 synaptotagmin XIII 1.15763
APRT adenine phosphoribosyltransferase 1.15729
ARRB1 arrestin, beta 1 1.15729
APAF1 apoptotic peptidase activating factor 1 1.15492
INS insulin 1.15391
PTK2 protein tyrosine kinase 2 1.1529
EPHX2 epoxide hydrolase 2, cytoplasmic 1.1529
MAP2 microtubule-associated protein 2 1.1529
TFAM transcription factor A, mitochondrial 1.1529
VGF VGF nerve growth factor inducible 1.15256
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 1.15256
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 1.15223
MAP2K1 mitogen-activated protein kinase kinase 1 1.15223
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.15156
ARNT aryl hydrocarbon receptor nuclear translocator 1.15089
CYBA cytochrome b-245, alpha polypeptide 1.15055
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.14885
ASIC3 acid sensing (proton gated) ion channel 3 1.14885
CYBB cytochrome b-245, beta polypeptide 1.1485
GDF11 growth differentiation factor 11 1.14816
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.14438
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.1437
TUBA1A tubulin, alpha 1a 1.1437
SYK spleen tyrosine kinase 1.14268
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.14268
PLCG1 phospholipase C, gamma 1 1.14064
HAL histidine ammonia-lyase 1.14064
CBS cystathionine-beta-synthase 1.14064
PRDX1 peroxiredoxin 1 1.1403
MAP2K2 mitogen-activated protein kinase kinase 2 1.1403
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.13929
PTEN phosphatase and tensin homolog 1.13862
ACSL1 acyl-CoA synthetase long-chain family member 1 1.13827
TXN thioredoxin 1.13827
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.13793
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.13793
EZR ezrin 1.13484
CYR61 cysteine-rich, angiogenic inducer, 61 1.13449
RRM2 ribonucleotide reductase M2 1.13449
IRS1 insulin receptor substrate 1 1.13449
CRIP1 cysteine-rich protein 1 (intestinal) 1.13347
POU2F1 POU class 2 homeobox 1 1.13347
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.13279
KRT8 keratin 8, type II 1.13245
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.13211
ACO1 aconitase 1, soluble 1.13211
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.13211
G6PC3 glucose 6 phosphatase, catalytic, 3 1.13109
SYNM synemin, intermediate filament protein 1.13075
CCND3 cyclin D3 1.13041
PTH parathyroid hormone 1.1294
INHBE inhibin, beta E 1.1294
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.12906
ACSL6 acyl-CoA synthetase long-chain family member 6 1.12906
PFKM phosphofructokinase, muscle 1.12906
NPPA natriuretic peptide A 1.12805
XDH xanthine dehydrogenase 1.12805
PHGDH phosphoglycerate dehydrogenase 1.12668
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.12634
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.12634
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.12461
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.12461
ACTN1 actinin, alpha 1 1.12461
SLIT2 slit homolog 2 (Drosophila) 1.12461
BCHE butyrylcholinesterase 1.12391
S100B S100 calcium binding protein B 1.12357
ECH1 enoyl CoA hydratase 1, peroxisomal 1.12357
AVPR1B arginine vasopressin receptor 1B 1.12288
ATG3 autophagy related 3 1.12288
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.12117
HSPA1B heat shock 70kDa protein 1B 1.12082
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.12082
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.12048
SRGN serglycin 1.12014
BAK1 BCL2-antagonist/killer 1 1.11877
DCN decorin 1.11843
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.11809
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.11707
DPYSL2 dihydropyrimidinase-like 2 1.11606
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.11571
ASPA aspartoacylase 1.11571
FST follistatin 1.11571
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.11536
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.11501
NDRG1 N-myc downstream regulated 1 1.11501
CHDH choline dehydrogenase 1.11501
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.10769
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.10769
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.10769
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.10769
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 1.10734
PHB prohibitin 1.10734
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.10734
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 1.10734
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.10734
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.10699
CHRM3 cholinergic receptor, muscarinic 3 1.10493
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.10493
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.10388
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.10353
CROT carnitine O-octanoyltransferase 1.10353
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.10353
PEX11A peroxisomal biogenesis factor 11 alpha 1.10317
TXNL1 thioredoxin-like 1 1.10317
E2F1 E2F transcription factor 1 1.10211
KLF9 Kruppel-like factor 9 1.10211
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.10211
CDK4 cyclin-dependent kinase 4 1.09998
MXRA7 matrix-remodelling associated 7 1.09998
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.09998
OPRK1 opioid receptor, kappa 1 1.09963
MLYCD malonyl-CoA decarboxylase 1.09963
ANGPT2 angiopoietin 2 1.09927
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.09927
CTSB cathepsin B 1.09857
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.09751
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.09716
TUBA4A tubulin, alpha 4a 1.09541
RPS19 ribosomal protein S19 1.09506
ACTB actin, beta 1.09297
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.0919
ADORA2A adenosine A2a receptor 1.0919
HMGB2 high mobility group box 2 1.0919
CCR2 chemokine (C-C motif) receptor 2 1.0919
LHB luteinizing hormone beta polypeptide 1.09047
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 1.08975
G0S2 G0/G1 switch 2 1.0894
TF transferrin 1.08762
AKR1D1 aldo-keto reductase family 1, member D1 1.08726
ATF2 activating transcription factor 2 1.0869
DCAF8 DDB1 and CUL4 associated factor 8 1.08584
CD44 CD44 molecule (Indian blood group) 1.08584
GNB5 guanine nucleotide binding protein (G protein), beta 5 1.08584
IGF1R insulin-like growth factor 1 receptor 1.08407
C10ORF10 chromosome 10 open reading frame 10 1.08372
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.08337
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.08337
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.08337
FAT1 FAT atypical cadherin 1 1.08337
IFRD1 interferon-related developmental regulator 1 1.08196
NOX4 NADPH oxidase 4 1.08196
ELOVL5 ELOVL fatty acid elongase 5 1.07983
MSMO1 methylsterol monooxygenase 1 1.07947
CTSD cathepsin D 1.07911
PCBP1 poly(rC) binding protein 1 1.07875
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 1.07875
PXMP4 peroxisomal membrane protein 4, 24kDa 1.07875
KIFC3 kinesin family member C3 1.07875
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.07732
FABP2 fatty acid binding protein 2, intestinal 1.07589
PROSER3 proline and serine rich 3 1.07482
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.07482
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.07482
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.07482
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.07482
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.07376
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.07234
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.07234
MTTP microsomal triglyceride transfer protein 1.07234
BST1 bone marrow stromal cell antigen 1 1.07199
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.07199
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.07057
INSR insulin receptor 1.06987
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.06987
PRKCD protein kinase C, delta 1.06881
ACADVL acyl-CoA dehydrogenase, very long chain 1.06881
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.06881
ACADL acyl-CoA dehydrogenase, long chain 1.06881
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.06844
INHBA inhibin, beta A 1.06771
IDI1 isopentenyl-diphosphate delta isomerase 1 1.06771
FMO1 flavin containing monooxygenase 1 1.06771
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.06734
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.06625
NOVA1 neuro-oncological ventral antigen 1 1.06588
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.06515
F2R coagulation factor II (thrombin) receptor 1.06515
HMGB1 high mobility group box 1 1.06515
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.06515
HTRA1 HtrA serine peptidase 1 1.06479
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.06479
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.06479
APP amyloid beta (A4) precursor protein 1.06442
GFAP glial fibrillary acidic protein 1.0637
FLT1 fms-related tyrosine kinase 1 1.06297
CCNE2 cyclin E2 1.06297
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.06152
PTMA prothymosin, alpha 1.06116
F2 coagulation factor II (thrombin) 1.06044
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.06044
PDIA3 protein disulfide isomerase family A, member 3 1.06044
HOXA5 homeobox A5 1.05972
OAT ornithine aminotransferase 1.05828
S1PR1 sphingosine-1-phosphate receptor 1 1.05793
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.05793
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.05721
TPM1 tropomyosin 1 (alpha) 1.0561
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.0561
ALAD aminolevulinate dehydratase 1.0561
NOS1 nitric oxide synthase 1 (neuronal) 1.05573
AK4 adenylate kinase 4 1.05423
ERP29 endoplasmic reticulum protein 29 1.05423
OSGIN1 oxidative stress induced growth inhibitor 1 1.05423
TXN2 thioredoxin 2 1.05423
GLUD1 glutamate dehydrogenase 1 1.05423
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 1.05312
TYK2 tyrosine kinase 2 1.05312
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.05089
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.05089
ACOT2 acyl-CoA thioesterase 2 1.05052
AHR aryl hydrocarbon receptor 1.05052
MT2A metallothionein 2A 1.04904
ADORA1 adenosine A1 receptor 1.04904
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.04757
PF4 platelet factor 4 1.04721
ABAT 4-aminobutyrate aminotransferase 1.04721
GRM2 glutamate receptor, metabotropic 2 1.04721
GRIK2 glutamate receptor, ionotropic, kainate 2 1.04721
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.04684
TJP1 tight junction protein 1 1.04684
CCL4 chemokine (C-C motif) ligand 4 1.04574
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.04465
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.04465
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.04427
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.04427
CREBBP CREB binding protein 1.04239
ASIC1 acid sensing (proton gated) ion channel 1 1.04163
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 1.04126
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 1.04088
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 1.04088
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.04051
CES2 carboxylesterase 2 1.04014
CDK6 cyclin-dependent kinase 6 1.03789
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.03789
ASIC2 acid sensing (proton gated) ion channel 2 1.03641
ADRBK1 adrenergic, beta, receptor kinase 1 1.0353
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.0353
PDE3B phosphodiesterase 3B, cGMP-inhibited 1.0353
FNTB farnesyltransferase, CAAX box, beta 1.0353
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.03493
SCG5 secretogranin V 1.03493
HDGF hepatoma-derived growth factor 1.03493
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.03345
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.03084
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.03046
SYP synaptophysin 1.03046
MPST mercaptopyruvate sulfurtransferase 1.03009
GPM6A glycoprotein M6A 1.03009
TFR2 transferrin receptor 2 1.02971
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 1.02971
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.02933
NME7 NME/NM23 family member 7 1.02933
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.02746
ZWINT ZW10 interacting kinetochore protein 1.02708
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.02708
RPSA ribosomal protein SA 1.02708
ACSL3 acyl-CoA synthetase long-chain family member 3 1.02708
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.02485
NRF1 nuclear respiratory factor 1 1.02447
E2F8 E2F transcription factor 8 1.0241
SELM selenoprotein M 1.0241
LCAT lecithin-cholesterol acyltransferase 1.0241
NREP neuronal regeneration related protein 1.0241
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.0241
HEXA hexosaminidase A (alpha polypeptide) 1.0241
PICALM phosphatidylinositol binding clathrin assembly protein 1.0241
PXMP2 peroxisomal membrane protein 2, 22kDa 1.02373
PKM pyruvate kinase, muscle 1.02299
PIR pirin (iron-binding nuclear protein) 1.02114
KCNK15 potassium channel, two pore domain subfamily K, member 15 1.02114
ACOT1 acyl-CoA thioesterase 1 1.02077
ADCY6 adenylate cyclase 6 1.0189
RPL32 ribosomal protein L32 1.0189
ASGR1 asialoglycoprotein receptor 1 1.01852
STXBP1 syntaxin binding protein 1 1.01852
PMVK phosphomevalonate kinase 1.01852
ACAT2 acetyl-CoA acetyltransferase 2 1.01776
COL18A1 collagen, type XVIII, alpha 1 1.01776
RGS4 regulator of G-protein signaling 4 1.01512
CCNF cyclin F 1.01474
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 1.01399
PLAT plasminogen activator, tissue 1.01361
TRAF5 TNF receptor-associated factor 5 1.01361
IL18 interleukin 18 1.01361
DDR2 discoidin domain receptor tyrosine kinase 2 1.01361
INA internexin neuronal intermediate filament protein, alpha 1.01324
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.01324
GJA4 gap junction protein, alpha 4, 37kDa 1.01324
ACTG1 actin gamma 1 1.01174
TKT transketolase 1.01174