ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation]_[GEO accession]_[perturbation ID]_[organism]_[cell or tissue] (Gene Expression Omnibus)
External Link
Similar Terms
Downloads & Tools


448 genes differentially expressed following the ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name
AADACP1 arylacetamide deacetylase pseudogene 1
AANAT aralkylamine N-acetyltransferase
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACP1 acid phosphatase 1, soluble
ACP2 acid phosphatase 2, lysosomal
ACTL9 actin-like 9
AKR1C4 aldo-keto reductase family 1, member C4
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMELY amelogenin, Y-linked
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AQP4-AS1 AQP4 antisense RNA 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARSD arylsulfatase D
ATG10 autophagy related 10
ATP11A-AS1 ATP11A antisense RNA 1
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BHLHE41 basic helix-loop-helix family, member e41
BSG basigin (Ok blood group)
BTNL9 butyrophilin-like 9
C12ORF40 chromosome 12 open reading frame 40
C7ORF60 chromosome 7 open reading frame 60
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CATSPER2 cation channel, sperm associated 2
CCDC112 coiled-coil domain containing 112
CCL19 chemokine (C-C motif) ligand 19
CCNL1 cyclin L1
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CDK17 cyclin-dependent kinase 17
CDRT15 CMT1A duplicated region transcript 15
CES1P1 carboxylesterase 1 pseudogene 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRD chordin
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLINT1 clathrin interactor 1
CLIP1-AS1 CLIP1 antisense RNA 1
COL6A5 collagen, type VI, alpha 5
COL7A1 collagen, type VII, alpha 1
COPS5 COP9 signalosome subunit 5
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRYGA crystallin, gamma A
CSPG4 chondroitin sulfate proteoglycan 4
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYTIP cytohesin 1 interacting protein
DCLRE1C DNA cross-link repair 1C
DDIT4 DNA-damage-inducible transcript 4
DEFB119 defensin, beta 119
DMP1 dentin matrix acidic phosphoprotein 1
EDNRB endothelin receptor type B
ERH enhancer of rudimentary homolog (Drosophila)
F11R F11 receptor
FABP2 fatty acid binding protein 2, intestinal
FAM178B family with sequence similarity 178, member B
FAM9C family with sequence similarity 9, member C
FGF21 fibroblast growth factor 21
FKBP11 FK506 binding protein 11, 19 kDa
FLJ31356 uncharacterized protein FLJ31356
FMO1 flavin containing monooxygenase 1
G6PC3 glucose 6 phosphatase, catalytic, 3
GIPC1 GIPC PDZ domain containing family, member 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPR84 G protein-coupled receptor 84
GRASPOS GRP1-associated scaffold protein opposite strand
GRPR gastrin-releasing peptide receptor
GSX1 GS homeobox 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HHCM Mahlavu hepatocellular carcinoma
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIST1H4I histone cluster 1, H4i
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HRES1 HTLV-1 related endogenous sequence
HRH4 histamine receptor H4
HSPC081 uncharacterized LOC100286989
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGHV5-78 immunoglobulin heavy variable 5-78 (pseudogene)
IGLV1-36 immunoglobulin lambda variable 1-36
IGSF6 immunoglobulin superfamily, member 6
INHBE inhibin, beta E
KRT19 keratin 19, type I
KRT222 keratin 222, type II
KRT77 keratin 77, type II
LEMD1-AS1 LEMD1 antisense RNA 1
LIMK1 LIM domain kinase 1
LIN28A lin-28 homolog A (C. elegans)
LINC00271 long intergenic non-protein coding RNA 271
LINC00320 long intergenic non-protein coding RNA 320
LINC00327 long intergenic non-protein coding RNA 327
LINC00355 long intergenic non-protein coding RNA 355
LINC00463 long intergenic non-protein coding RNA 463
LINC00557 long intergenic non-protein coding RNA 557
LINC00567 long intergenic non-protein coding RNA 567
LINC00610 long intergenic non-protein coding RNA 610
LINC01010 long intergenic non-protein coding RNA 1010
LINC01097 long intergenic non-protein coding RNA 1097
LINC01220 long intergenic non-protein coding RNA 1220
LINC01432 long intergenic non-protein coding RNA 1432
LINC01468 long intergenic non-protein coding RNA 1468
LOC100128554 uncharacterized LOC100128554
LOC100128843 uncharacterized LOC100128843
LOC100132686 uncharacterized LOC100132686
LOC100506258 uncharacterized LOC100506258
LOC100507140 uncharacterized LOC100507140
LOC101928167 uncharacterized LOC101928167
LOC101928211 uncharacterized LOC101928211
LOC101928710 uncharacterized LOC101928710
LOC101929413 uncharacterized LOC101929413
LOC101929586 uncharacterized LOC101929586
LOC146513 uncharacterized LOC146513
LOC151484 uncharacterized LOC151484
LOC284950 uncharacterized LOC284950
LOC339593 uncharacterized LOC339593
LOC401585 uncharacterized LOC401585
LOC439951 uncharacterized LOC439951
LPIN2 lipin 2
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
LYRM2 LYR motif containing 2
MAGEA12 melanoma antigen family A12
MAN1A2 mannosidase, alpha, class 1A, member 2
MED1 mediator complex subunit 1
MID1IP1 MID1 interacting protein 1
MIOX myo-inositol oxygenase
MIR210HG MIR210 host gene
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
NALCN sodium leak channel, non selective
NCAPD2 non-SMC condensin I complex, subunit D2
NDUFV2-AS1 NDUFV2 antisense RNA 1
NOA1 nitric oxide associated 1
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP133 nucleoporin 133kDa
NUPL2 nucleoporin like 2
OFCC1 orofacial cleft 1 candidate 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR51B4 olfactory receptor, family 51, subfamily B, member 4
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PANX3 pannexin 3
PAPD5 PAP associated domain containing 5
PAX2 paired box 2
PDZD7 PDZ domain containing 7
PEX5 peroxisomal biogenesis factor 5
PHAX phosphorylated adaptor for RNA export
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
PMP2 peripheral myelin protein 2
PNOC prepronociceptin
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRPF3 pre-mRNA processing factor 3
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTPRG-AS1 PTPRG antisense RNA 1
PTPRJ protein tyrosine phosphatase, receptor type, J
PYDC1 PYD (pyrin domain) containing 1
PYHIN1 pyrin and HIN domain family, member 1
PYY2 peptide YY, 2 (pseudogene)
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RARS arginyl-tRNA synthetase
RBP5 retinol binding protein 5, cellular
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIT2 Ras-like without CAAX 2
RNASEH2B ribonuclease H2, subunit B
RNF13 ring finger protein 13
RPL28 ribosomal protein L28
RPS10 ribosomal protein S10
SBF2 SET binding factor 2
SCGB1D1 secretoglobin, family 1D, member 1
SETD5 SET domain containing 5
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SLC22A31 solute carrier family 22, member 31
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SNTN sentan, cilia apical structure protein
SOST sclerostin
SPACA1 sperm acrosome associated 1
SPRR2C small proline-rich protein 2C (pseudogene)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SSU72P3 SSU72 pseudogene 3
ST7-OT4 ST7 overlapping transcript 4
STARD7 StAR-related lipid transfer (START) domain containing 7
STGC3 uncharacterized STGC3
STXBP1 syntaxin binding protein 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCERG1L transcription elongation regulator 1-like
TEDDM1 transmembrane epididymal protein 1
TEX29 testis expressed 29
TGIF2LY TGFB-induced factor homeobox 2-like, Y-linked
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM57 transmembrane protein 57
TMEM75 transmembrane protein 75
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TP53I11 tumor protein p53 inducible protein 11
TRAM2-AS1 TRAM2 antisense RNA 1 (head to head)
TRERF1 transcriptional regulating factor 1
TRIB3 tribbles pseudokinase 3
TRIM25 tripartite motif containing 25
UBE2Z ubiquitin-conjugating enzyme E2Z
UBQLN3 ubiquilin 3
USP35 ubiquitin specific peptidase 35
VNN2 vanin 2
VWA3A von Willebrand factor A domain containing 3A
VWCE von Willebrand factor C and EGF domains
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
ZBTB33 zinc finger and BTB domain containing 33
ZIK1 zinc finger protein interacting with K protein 1
ZNF517 zinc finger protein 517
ZNF572 zinc finger protein 572
ZNF93 zinc finger protein 93
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ADCY8 adenylate cyclase 8 (brain)
ADRBK1 adrenergic, beta, receptor kinase 1
AGFG1 ArfGAP with FG repeats 1
AGRP agouti related neuropeptide
AKTIP AKT interacting protein
API5 apoptosis inhibitor 5
ARL1 ADP-ribosylation factor-like 1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAGE B melanoma antigen
BCL2L2 BCL2-like 2
C11ORF80 chromosome 11 open reading frame 80
C1QBP complement component 1, q subcomponent binding protein
C20ORF187 chromosome 20 open reading frame 187
CBX3 chromobox homolog 3
CCDC158 coiled-coil domain containing 158
CCDC174 coiled-coil domain containing 174
CCDC54 coiled-coil domain containing 54
CCDC77 coiled-coil domain containing 77
CCDC91 coiled-coil domain containing 91
CCR8 chemokine (C-C motif) receptor 8
CD8B CD8b molecule
CDC25B cell division cycle 25B
CDRT15L2 CMT1A duplicated region transcript 15-like 2
CENPB centromere protein B, 80kDa
CHAD chondroadherin
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CHIAP2 chitinase, acidic pseudogene 2
CHRM4 cholinergic receptor, muscarinic 4
CLCA1 chloride channel accessory 1
COL6A2 collagen, type VI, alpha 2
CORO1B coronin, actin binding protein, 1B
CTRC chymotrypsin C (caldecrin)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
DAB1-AS1 DAB1 antisense RNA 1
DDC-AS1 DDC antisense RNA 1
DEDD death effector domain containing
DEFB127 defensin, beta 127
DEGS1 delta(4)-desaturase, sphingolipid 1
DIO1 deiodinase, iodothyronine, type I
DNAH17-AS1 DNAH17 antisense RNA 1
DNAJC27-AS1 DNAJC27 antisense RNA 1
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
EIF4A1 eukaryotic translation initiation factor 4A1
EMC1 ER membrane protein complex subunit 1
FAAH2 fatty acid amide hydrolase 2
FAM153B family with sequence similarity 153, member B
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBXO39 F-box protein 39
FERMT3 fermitin family member 3
FGL2 fibrinogen-like 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FIBP fibroblast growth factor (acidic) intracellular binding protein
FOXE3 forkhead box E3
FSD2 fibronectin type III and SPRY domain containing 2
GAL3ST3 galactose-3-O-sulfotransferase 3
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9
GCKR glucokinase (hexokinase 4) regulator
GHR growth hormone receptor
GJB2 gap junction protein, beta 2, 26kDa
GOLM1 golgi membrane protein 1
GPHB5 glycoprotein hormone beta 5
GPR162 G protein-coupled receptor 162
GPR183 G protein-coupled receptor 183
GTF2A2 general transcription factor IIA, 2, 12kDa
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa
GYPE glycophorin E (MNS blood group)
HAUS2 HAUS augmin-like complex, subunit 2
HAUS5 HAUS augmin-like complex, subunit 5
HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis)
HIST1H4PS1 histone cluster 1, H4, pseudogene 1
HJURP Holliday junction recognition protein
HSPA9 heat shock 70kDa protein 9 (mortalin)
IFI27 interferon, alpha-inducible protein 27
IGIP IgA-inducing protein
IL5 interleukin 5
IQCH-AS1 IQCH antisense RNA 1
ISX intestine-specific homeobox
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDELC2 KDEL (Lys-Asp-Glu-Leu) containing 2
KIAA0509 uncharacterized LOC57242
KRT27 keratin 27, type I
KRT71 keratin 71, type II
LCN1 lipocalin 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHFPL1 lipoma HMGIC fusion partner-like 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LIMCH1 LIM and calponin homology domains 1
LINC00167 long intergenic non-protein coding RNA 167
LINC00293 long intergenic non-protein coding RNA 293
LINC00477 long intergenic non-protein coding RNA 477
LINC00659 long intergenic non-protein coding RNA 659
LINC00951 long intergenic non-protein coding RNA 951
LINC00997 long intergenic non-protein coding RNA 997
LINC01069 long intergenic non-protein coding RNA 1069
LINC01213 long intergenic non-protein coding RNA 1213
LINC01214 long intergenic non-protein coding RNA 1214
LINC01289 long intergenic non-protein coding RNA 1289
LINC01346 long intergenic non-protein coding RNA 1346
LOC100130741 uncharacterized LOC100130741
LOC100132167 uncharacterized LOC100132167
LOC100134368 uncharacterized LOC100134368
LOC100506585 uncharacterized LOC100506585
LOC101927181 uncharacterized LOC101927181
LOC101927650 uncharacterized LOC101927650
LOC101928333 uncharacterized LOC101928333
LOC101928418 uncharacterized LOC101928418
LOC101928446 uncharacterized LOC101928446
LOC101928661 uncharacterized LOC101928661
LOC101928995 uncharacterized LOC101928995
LOC101929622 uncharacterized LOC101929622
LOC142937 uncharacterized protein BC008131
LOC145678 uncharacterized LOC145678
LOC284294 uncharacterized LOC284294
LOC284630 uncharacterized LOC284630
LOC284648 uncharacterized LOC284648
LOC285819 uncharacterized LOC285819
LOC286370 uncharacterized LOC286370
LOC340178 uncharacterized LOC340178
LOC340340 uncharacterized LOC340340
LOC647323 uncharacterized LOC647323
LOC653602 uncharacterized LOC653602
LRRC52 leucine rich repeat containing 52
LRRC8C leucine rich repeat containing 8 family, member C
LRRK2 leucine-rich repeat kinase 2
LRRN1 leucine rich repeat neuronal 1
LY86 lymphocyte antigen 86
LYPLA1 lysophospholipase I
LZTS1-AS1 LZTS1 antisense RNA 1
MBD4 methyl-CpG binding domain protein 4
MCM5 minichromosome maintenance complex component 5
MS4A5 membrane-spanning 4-domains, subfamily A, member 5
MTMR8 myotubularin related protein 8
MUC19 mucin 19, oligomeric
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH16 myosin, heavy chain 16 pseudogene
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NKX2-3 NK2 homeobox 3
NLRP8 NLR family, pyrin domain containing 8
NOL11 nucleolar protein 11
NOTUM notum pectinacetylesterase homolog (Drosophila)
NPR1 natriuretic peptide receptor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
OPRD1 opioid receptor, delta 1
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARK7 parkinson protein 7
PIK3IP1-AS1 PIK3IP1 antisense RNA 1 (head to head)
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing
PLCD4 phospholipase C, delta 4
PNPLA8 patatin-like phospholipase domain containing 8
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPAP2C phosphatidic acid phosphatase type 2C
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP4C protein phosphatase 4, catalytic subunit
PRDM14 PR domain containing 14
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTH2 parathyroid hormone 2
PTK6 protein tyrosine kinase 6
RACGAP1P Rac GTPase activating protein 1 pseudogene
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBMXL2 RNA binding motif protein, X-linked-like 2
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RHO rhodopsin
RLIM ring finger protein, LIM domain interacting
RP1L1 retinitis pigmentosa 1-like 1
RSBN1L round spermatid basic protein 1-like
RYBP RING1 and YY1 binding protein
SCLY selenocysteine lyase
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDC4 syndecan 4
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIAH1 siah E3 ubiquitin protein ligase 1
SLAIN1 SLAIN motif family, member 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC30A6 solute carrier family 30 (zinc transporter), member 6
SLMO1 slowmo homolog 1 (Drosophila)
SMIM5 small integral membrane protein 5
SMIM6 small integral membrane protein 6
SOAT2 sterol O-acyltransferase 2
ST7 suppression of tumorigenicity 7
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUN3 Sad1 and UNC84 domain containing 3
SYCE3 synaptonemal complex central element protein 3
TECTB tectorin beta
TGFBI transforming growth factor, beta-induced, 68kDa
THAP6 THAP domain containing 6
TLDC2 TBC/LysM-associated domain containing 2
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TNPO3 transportin 3
TRIM17 tripartite motif containing 17
TRIM40 tripartite motif containing 40
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
UBQLN1 ubiquilin 1
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UNC50 unc-50 homolog (C. elegans)
UQCRC1 ubiquinol-cytochrome c reductase core protein I
URGCP upregulator of cell proliferation
USP29 ubiquitin specific peptidase 29
VAV1 vav 1 guanine nucleotide exchange factor
VIMP VCP-interacting membrane selenoprotein
ZBED2 zinc finger, BED-type containing 2
ZBTB8A zinc finger and BTB domain containing 8A
ZC3H14 zinc finger CCCH-type containing 14
ZC3H7A zinc finger CCCH-type containing 7A
ZNF222 zinc finger protein 222
ZNF232 zinc finger protein 232
ZNF442 zinc finger protein 442
ZNF550 zinc finger protein 550
ZNF609 zinc finger protein 609
ZNF791 zinc finger protein 791
ZNF831 zinc finger protein 831