5230742-862 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the 5230742-862 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACRV1 acrosomal vesicle protein 1
AHCYL2 adenosylhomocysteinase-like 2
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ATP9B ATPase, class II, type 9B
B9D1 B9 protein domain 1
BAK1 BCL2-antagonist/killer 1
BTBD7 BTB (POZ) domain containing 7
C22ORF46 chromosome 22 open reading frame 46
C7ORF69 chromosome 7 open reading frame 69
CACFD1 calcium channel flower domain containing 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACYBP calcyclin binding protein
CASZ1 castor zinc finger 1
CFAP44 cilia and flagella associated protein 44
CLUAP1 clusterin associated protein 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CRELD1 cysteine-rich with EGF-like domains 1
CRTC1 CREB regulated transcription coactivator 1
CSNK1G1 casein kinase 1, gamma 1
CSRP2 cysteine and glycine-rich protein 2
CTNS cystinosin, lysosomal cystine transporter
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DOC2A double C2-like domains, alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDRF1 erythroid differentiation regulatory factor 1
FAM214B family with sequence similarity 214, member B
FHL1 four and a half LIM domains 1
FLJ42627 uncharacterized LOC645644
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FNDC3A fibronectin type III domain containing 3A
GAB1 GRB2-associated binding protein 1
GOSR2 golgi SNAP receptor complex member 2
GRM8 glutamate receptor, metabotropic 8
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IDS iduronate 2-sulfatase
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IPO8 importin 8
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
KREMEN2 kringle containing transmembrane protein 2
LHX1 LIM homeobox 1
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAP9 microtubule-associated protein 9
MARC2 mitochondrial amidoxime reducing component 2
MBD1 methyl-CpG binding domain protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MMRN2 multimerin 2
MTSS1 metastasis suppressor 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH4 myosin, heavy chain 4, skeletal muscle
NENF neudesin neurotrophic factor
NF2 neurofibromin 2 (merlin)
NNAT neuronatin
NR2C1 nuclear receptor subfamily 2, group C, member 1
OSMR oncostatin M receptor
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PDLIM5 PDZ and LIM domain 5
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKD2L2 polycystic kidney disease 2-like 2
POMT2 protein-O-mannosyltransferase 2
PRDM2 PR domain containing 2, with ZNF domain
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PVT1 Pvt1 oncogene (non-protein coding)
RANBP1 RAN binding protein 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPL7 ribosomal protein L7
RRP1B ribosomal RNA processing 1B
RTN2 reticulon 2
SAMD9 sterile alpha motif domain containing 9
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SLC12A8 solute carrier family 12, member 8
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
STK3 serine/threonine kinase 3
TBC1D5 TBC1 domain family, member 5
TMC5 transmembrane channel-like 5
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TPMT thiopurine S-methyltransferase
TTLL5 tubulin tyrosine ligase-like family member 5
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDFY3 WD repeat and FYVE domain containing 3
WDR55 WD repeat domain 55
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF44 zinc finger protein 44
ZNF440 zinc finger protein 440
ZNF573 zinc finger protein 573
ZNF783 zinc finger family member 783
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ARHGAP12 Rho GTPase activating protein 12
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASB7 ankyrin repeat and SOCS box containing 7
ATG2A autophagy related 2A
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CDKL3 cyclin-dependent kinase-like 3
CFD complement factor D (adipsin)
CLEC16A C-type lectin domain family 16, member A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRLF1 cytokine receptor-like factor 1
CTNNBIP1 catenin, beta interacting protein 1
CTPS1 CTP synthase 1
CXORF56 chromosome X open reading frame 56
DEPDC1 DEP domain containing 1
DNAL4 dynein, axonemal, light chain 4
DUSP22 dual specificity phosphatase 22
ECI1 enoyl-CoA delta isomerase 1
EGR3 early growth response 3
EIF3L eukaryotic translation initiation factor 3, subunit L
ETAA1 Ewing tumor-associated antigen 1
FAAH fatty acid amide hydrolase
FBXO22 F-box protein 22
FCHSD2 FCH and double SH3 domains 2
FKBP2 FK506 binding protein 2, 13kDa
GAA glucosidase, alpha; acid
GATA4 GATA binding protein 4
GFOD1 glucose-fructose oxidoreductase domain containing 1
GGNBP2 gametogenetin binding protein 2
GMEB1 glucocorticoid modulatory element binding protein 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HOXC11 homeobox C11
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM7A lysine (K)-specific demethylase 7A
KIAA0196 KIAA0196
KIFAP3 kinesin-associated protein 3
KRT86 keratin 86, type II
LINS lines homolog (Drosophila)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
LRRC49 leucine rich repeat containing 49
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NUBPL nucleotide binding protein-like
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSTF1 osteoclast stimulating factor 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PMCH pro-melanin-concentrating hormone
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PRR15L proline rich 15-like
PSKH1 protein serine kinase H1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RARS arginyl-tRNA synthetase
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM14 RNA binding motif protein 14
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF113A ring finger protein 113A
RNF170 ring finger protein 170
SDC3 syndecan 3
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMCO4 single-pass membrane protein with coiled-coil domains 4
SP1 Sp1 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
SREK1IP1 SREK1-interacting protein 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TARP TCR gamma alternate reading frame protein
TCEAL1 transcription elongation factor A (SII)-like 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFB3 transforming growth factor, beta 3
TMEM62 transmembrane protein 62
TMEM8A transmembrane protein 8A
TRAF2 TNF receptor-associated factor 2
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
UNC13B unc-13 homolog B (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VKORC1 vitamin K epoxide reductase complex, subunit 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H3 zinc finger CCCH-type containing 3