5213008-898 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the 5213008-898 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK2 adenylate kinase 2
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOM apolipoprotein M
ARHGAP1 Rho GTPase activating protein 1
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BCORL1 BCL6 corepressor-like 1
BMP8B bone morphogenetic protein 8b
BTF3P12 basic transcription factor 3 pseudogene 12
C4ORF29 chromosome 4 open reading frame 29
CCP110 centriolar coiled coil protein 110kDa
CDK13 cyclin-dependent kinase 13
CEP290 centrosomal protein 290kDa
CFDP1 craniofacial development protein 1
COL8A1 collagen, type VIII, alpha 1
CRELD1 cysteine-rich with EGF-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIAPH1 diaphanous-related formin 1
DIO2 deiodinase, iodothyronine, type II
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP4 dual specificity phosphatase 4
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAS Fas cell surface death receptor
FNDC3A fibronectin type III domain containing 3A
FOXJ3 forkhead box J3
FRS2 fibroblast growth factor receptor substrate 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GREB1 growth regulation by estrogen in breast cancer 1
HIPK3 homeodomain interacting protein kinase 3
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
INHBA inhibin, beta A
IPO8 importin 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK3 Janus kinase 3
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLHL22 kelch-like family member 22
KLHL24 kelch-like family member 24
LIMCH1 LIM and calponin homology domains 1
LPIN2 lipin 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4 microtubule-associated protein 4
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MDM4 MDM4, p53 regulator
MED14 mediator complex subunit 14
MOCS1 molybdenum cofactor synthesis 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTAP methylthioadenosine phosphorylase
NBPF10 neuroblastoma breakpoint family, member 10
NF2 neurofibromin 2 (merlin)
NFRKB nuclear factor related to kappaB binding protein
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLAUR plasminogen activator, urokinase receptor
PRDX2 peroxiredoxin 2
PSPH phosphoserine phosphatase
PTPRA protein tyrosine phosphatase, receptor type, A
RASA2 RAS p21 protein activator 2
SAMD4A sterile alpha motif domain containing 4A
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SIKE1 suppressor of IKBKE 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
STARD3 StAR-related lipid transfer (START) domain containing 3
SUGP1 SURP and G patch domain containing 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TRA2A transformer 2 alpha homolog (Drosophila)
TREX1 three prime repair exonuclease 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBGCP3 tubulin, gamma complex associated protein 3
TWF1 twinfilin actin binding protein 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
VAV2 vav 2 guanine nucleotide exchange factor
VIPR1 vasoactive intestinal peptide receptor 1
WAS Wiskott-Aldrich syndrome
ZNF227 zinc finger protein 227
ZNF37BP zinc finger protein 37B, pseudogene
ZNF589 zinc finger protein 589
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSF2 acyl-CoA synthetase family member 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3A AT rich interactive domain 3A (BRIGHT-like)
AZI2 5-azacytidine induced 2
BAHD1 bromo adjacent homology domain containing 1
C1ORF115 chromosome 1 open reading frame 115
C6ORF47 chromosome 6 open reading frame 47
CBR1 carbonyl reductase 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKL3 cyclin-dependent kinase-like 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPO centromere protein O
CFD complement factor D (adipsin)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DSPP dentin sialophosphoprotein
EGR3 early growth response 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FBRS fibrosin
GATA4 GATA binding protein 4
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR87 G protein-coupled receptor 87
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC4 histone deacetylase 4
HIST1H3B histone cluster 1, H3b
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL15RA interleukin 15 receptor, alpha
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
IRX5 iroquois homeobox 5
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
KIAA0556 KIAA0556
LAMB1 laminin, beta 1
LIME1 Lck interacting transmembrane adaptor 1
LOXL1 lysyl oxidase-like 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGOHB mago-nashi homolog B (Drosophila)
MAP1S microtubule-associated protein 1S
MAP6D1 MAP6 domain containing 1
MAP9 microtubule-associated protein 9
MCOLN1 mucolipin 1
MEIS1 Meis homeobox 1
MORC3 MORC family CW-type zinc finger 3
MT1H metallothionein 1H
MYL5 myosin, light chain 5, regulatory
NABP2 nucleic acid binding protein 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NLRX1 NLR family member X1
NSUN3 NOP2/Sun domain family, member 3
PALM paralemmin
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PES1 pescadillo ribosomal biogenesis factor 1
PGP phosphoglycolate phosphatase
PHACTR4 phosphatase and actin regulator 4
PMP22 peripheral myelin protein 22
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSKH1 protein serine kinase H1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPS17P5 ribosomal protein S17 pseudogene 5
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
STBD1 starch binding domain 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIGD6 tigger transposable element derived 6
TMPRSS4 transmembrane protease, serine 4
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNS2 tensin 2
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USP36 ubiquitin specific peptidase 36
WBP2 WW domain binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP30 ZFP30 zinc finger protein
ZNF571 zinc finger protein 571
ZNF574 zinc finger protein 574
ZNF668 zinc finger protein 668
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76