5211181-950 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5211181-950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALPK1 alpha-kinase 1
ANKRD26 ankyrin repeat domain 26
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARL4C ADP-ribosylation factor-like 4C
ARTN artemin
ATG3 autophagy related 3
BAX BCL2-associated X protein
BIN1 bridging integrator 1
CCDC186 coiled-coil domain containing 186
CDK3 cyclin-dependent kinase 3
CLDN15 claudin 15
CPNE7 copine VII
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYBG3 beta-gamma crystallin domain containing 3
CSNK1G1 casein kinase 1, gamma 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DESI2 desumoylating isopeptidase 2
DLX4 distal-less homeobox 4
DVL2 dishevelled segment polarity protein 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EML2 echinoderm microtubule associated protein like 2
EVA1B eva-1 homolog B (C. elegans)
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GLRX glutaredoxin (thioltransferase)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HLA-J major histocompatibility complex, class I, J (pseudogene)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM7A lysine (K)-specific demethylase 7A
KIAA1107 KIAA1107
KLHL24 kelch-like family member 24
KPNA5 karyopherin alpha 5 (importin alpha 6)
LPA lipoprotein, Lp(a)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAGEA3 melanoma antigen family A3
MAP1B microtubule-associated protein 1B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK14 mitogen-activated protein kinase 14
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MINK1 misshapen-like kinase 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFRKB nuclear factor related to kappaB binding protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRF1 nuclear respiratory factor 1
PAPOLA poly(A) polymerase alpha
PDCD2 programmed cell death 2
PDE4DIP phosphodiesterase 4D interacting protein
PDE9A phosphodiesterase 9A
PEX16 peroxisomal biogenesis factor 16
PEX7 peroxisomal biogenesis factor 7
PHF1 PHD finger protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLH polymerase (DNA directed), eta
PORCN porcupine homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
RECQL5 RecQ protein-like 5
RRAGD Ras-related GTP binding D
SAP30 Sin3A-associated protein, 30kDa
SIDT2 SID1 transmembrane family, member 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SP100 SP100 nuclear antigen
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STK16 serine/threonine kinase 16
TDRD3 tudor domain containing 3
TFE3 transcription factor binding to IGHM enhancer 3
TM4SF1 transmembrane 4 L six family member 1
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XK X-linked Kx blood group
YIPF2 Yip1 domain family, member 2
ZBTB48 zinc finger and BTB domain containing 48
ZFYVE26 zinc finger, FYVE domain containing 26

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABLIM3 actin binding LIM protein family, member 3
ARMC6 armadillo repeat containing 6
AXIN1 axin 1
BCL7C B-cell CLL/lymphoma 7C
C21ORF91 chromosome 21 open reading frame 91
CA11 carbonic anhydrase XI
CCP110 centriolar coiled coil protein 110kDa
CD3EAP CD3e molecule, epsilon associated protein
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
CPSF3L cleavage and polyadenylation specific factor 3-like
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSK cathepsin K
CUEDC1 CUE domain containing 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DUSP8 dual specificity phosphatase 8
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EGR3 early growth response 3
ELMO3 engulfment and cell motility 3
EPPK1 epiplakin 1
FAM179B family with sequence similarity 179, member B
FBRS fibrosin
FOXC1 forkhead box C1
FPGT fucose-1-phosphate guanylyltransferase
GALT galactose-1-phosphate uridylyltransferase
GPN2 GPN-loop GTPase 2
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC4 histone deacetylase 4
IFITM1 interferon induced transmembrane protein 1
IRF6 interferon regulatory factor 6
KAT2B K(lysine) acetyltransferase 2B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0125 KIAA0125
KIAA0355 KIAA0355
KLF3 Kruppel-like factor 3 (basic)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LINC00115 long intergenic non-protein coding RNA 115
LYPD3 LY6/PLAUR domain containing 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
METTL2B methyltransferase like 2B
MNX1 motor neuron and pancreas homeobox 1
MRPL2 mitochondrial ribosomal protein L2
MRPL44 mitochondrial ribosomal protein L44
MSX1 msh homeobox 1
MTA2 metastasis associated 1 family, member 2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO19 myosin XIX
NAV2 neuron navigator 2
NBEAL2 neurobeachin-like 2
NCAM2 neural cell adhesion molecule 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX26 peroxisomal biogenesis factor 26
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNPLA6 patatin-like phospholipase domain containing 6
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTGES2 prostaglandin E synthase 2
RAB5B RAB5B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBBP5 retinoblastoma binding protein 5
RBL1 retinoblastoma-like 1
RBM28 RNA binding motif protein 28
RECQL4 RecQ protein-like 4
RGS19 regulator of G-protein signaling 19
RIPK4 receptor-interacting serine-threonine kinase 4
RPH3AL rabphilin 3A-like (without C2 domains)
SIDT1 SID1 transmembrane family, member 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNORA21 small nucleolar RNA, H/ACA box 21
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TFF3 trefoil factor 3 (intestinal)
THOP1 thimet oligopeptidase 1
TMEM110 transmembrane protein 110
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRAPPC2 trafficking protein particle complex 2
TRIM66 tripartite motif containing 66
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3D tubulin, alpha 3d
WDR13 WD repeat domain 13
WDR91 WD repeat domain 91
ZNF226 zinc finger protein 226
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552