5211181-834 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 5211181-834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AKR1C3 aldo-keto reductase family 1, member C3
AXIN1 axin 1
B9D2 B9 protein domain 2
BBS4 Bardet-Biedl syndrome 4
CBX4 chromobox homolog 4
CCDC69 coiled-coil domain containing 69
CD58 CD58 molecule
CDC14B cell division cycle 14B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPTP ceramide-1-phosphate transfer protein
CRELD1 cysteine-rich with EGF-like domains 1
CREM cAMP responsive element modulator
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIO2 deiodinase, iodothyronine, type II
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
DUSP13 dual specificity phosphatase 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F4 E2F transcription factor 4, p107/p130-binding
EDRF1 erythroid differentiation regulatory factor 1
EFNA3 ephrin-A3
EIF3M eukaryotic translation initiation factor 3, subunit M
EML2 echinoderm microtubule associated protein like 2
EN2 engrailed homeobox 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC5 excision repair cross-complementation group 5
EXPH5 exophilin 5
FADS2 fatty acid desaturase 2
FADS3 fatty acid desaturase 3
FBXO46 F-box protein 46
FLJ22184
FNDC3A fibronectin type III domain containing 3A
GADD45A growth arrest and DNA-damage-inducible, alpha
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GPR153 G protein-coupled receptor 153
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IPO8 importin 8
KCNK1 potassium channel, two pore domain subfamily K, member 1
KHNYN KH and NYN domain containing
KREMEN2 kringle containing transmembrane protein 2
MAPK11 mitogen-activated protein kinase 11
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYO1E myosin IE
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NYNRIN NYN domain and retroviral integrase containing
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PASK PAS domain containing serine/threonine kinase
PDE12 phosphodiesterase 12
PDE4DIP phosphodiesterase 4D interacting protein
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PRPH peripherin
PSEN2 presenilin 2
RANBP1 RAN binding protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFTN1 raftlin, lipid raft linker 1
RNF208 ring finger protein 208
RNF24 ring finger protein 24
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SAPCD1 suppressor APC domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STYK1 serine/threonine/tyrosine kinase 1
SUMO1 small ubiquitin-like modifier 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TK2 thymidine kinase 2, mitochondrial
TMPRSS4 transmembrane protease, serine 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TTC28 tetratricopeptide repeat domain 28
USP27X ubiquitin specific peptidase 27, X-linked
VAMP4 vesicle-associated membrane protein 4
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WWTR1 WW domain containing transcription regulator 1
YTHDC2 YTH domain containing 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF444 zinc finger protein 444
ZNF473 zinc finger protein 473
ZNF692 zinc finger protein 692

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACOT8 acyl-CoA thioesterase 8
ACTL8 actin-like 8
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
C5ORF45 chromosome 5 open reading frame 45
CABP2 calcium binding protein 2
CEP97 centrosomal protein 97kDa
CINP cyclin-dependent kinase 2 interacting protein
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTAGE9 CTAGE family, member 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4C DENN/MADD domain containing 4C
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
FAN1 FANCD2/FANCI-associated nuclease 1
FBXW12 F-box and WD repeat domain containing 12
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
GALK1 galactokinase 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAUS2 HAUS augmin-like complex, subunit 2
HIST1H2BI histone cluster 1, H2bi
HIST1H3G histone cluster 1, H3g
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
IL17RA interleukin 17 receptor A
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF7 interferon regulatory factor 7
IRX4 iroquois homeobox 4
KAT2B K(lysine) acetyltransferase 2B
KRT15 keratin 15, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MCPH1 microcephalin 1
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
MUM1 melanoma associated antigen (mutated) 1
NUPL2 nucleoporin like 2
PARD6B par-6 family cell polarity regulator beta
PCDHB13 protocadherin beta 13
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POLL polymerase (DNA directed), lambda
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTOV1 prostate tumor overexpressed 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RNF2 ring finger protein 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUFY2 RUN and FYVE domain containing 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SFMBT1 Scm-like with four mbt domains 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC41A3 solute carrier family 41, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX15 sorting nexin 15
SP1 Sp1 transcription factor
SPATA1 spermatogenesis associated 1
STAG3 stromal antigen 3
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
TIGD6 tigger transposable element derived 6
TLN1 talin 1
TMEM165 transmembrane protein 165
TRIM52 tripartite motif containing 52
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP6 ubiquitin specific peptidase 6
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
ZNF329 zinc finger protein 329
ZNF45 zinc finger protein 45
ZNF551 zinc finger protein 551
ZNF552 zinc finger protein 552
ZNF611 zinc finger protein 611
ZNF813 zinc finger protein 813
ZNF84 zinc finger protein 84