5155877-6574 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the 5155877-6574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD3 abhydrolase domain containing 3
ACTB actin, beta
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APP amyloid beta (A4) precursor protein
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BAGE B melanoma antigen
BMP7 bone morphogenetic protein 7
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CBR3 carbonyl reductase 3
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTNS cystinosin, lysosomal cystine transporter
DDIT3 DNA-damage-inducible transcript 3
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DUSP5 dual specificity phosphatase 5
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
EPOR erythropoietin receptor
FGFR1OP FGFR1 oncogene partner
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FTL ferritin, light polypeptide
GADD45A growth arrest and DNA-damage-inducible, alpha
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCLM glutamate-cysteine ligase, modifier subunit
H2AFX H2A histone family, member X
HAUS5 HAUS augmin-like complex, subunit 5
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HMOX1 heme oxygenase 1
HPCAL1 hippocalcin-like 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1L heat shock 70kDa protein 1-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INO80B INO80 complex subunit B
IREB2 iron-responsive element binding protein 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
KCTD5 potassium channel tetramerization domain containing 5
KIAA1033 KIAA1033
LRRC41 leucine rich repeat containing 41
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MBOAT7 membrane bound O-acyltransferase domain containing 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MPDU1 mannose-P-dolichol utilization defect 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXD4 MAX dimerization protein 4
N4BP2L2 NEDD4 binding protein 2-like 2
NFYC nuclear transcription factor Y, gamma
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDAP1 PDGFA associated protein 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POFUT1 protein O-fucosyltransferase 1
PPIF peptidylprolyl isomerase F
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF4B pre-mRNA processing factor 4B
RAB5C RAB5C, member RAS oncogene family
RHOQ ras homolog family member Q
RPP25 ribonuclease P/MRP 25kDa subunit
RRM1 ribonucleotide reductase M1
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC41A3 solute carrier family 41, member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STIP1 stress-induced phosphoprotein 1
STX5 syntaxin 5
STYK1 serine/threonine/tyrosine kinase 1
TBL1X transducin (beta)-like 1X-linked
TES testin LIM domain protein
THBD thrombomodulin
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM161A transmembrane protein 161A
TMEM57 transmembrane protein 57
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TUBA3C tubulin, alpha 3c
TXNRD1 thioredoxin reductase 1
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACKR3 atypical chemokine receptor 3
AMPD2 adenosine monophosphate deaminase 2
APH1A APH1A gamma secretase subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX1 armadillo repeat containing, X-linked 1
ARPIN actin-related protein 2/3 complex inhibitor
ARSB arylsulfatase B
BAMBI BMP and activin membrane-bound inhibitor
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF30 chromosome 11 open reading frame 30
C1ORF105 chromosome 1 open reading frame 105
C22ORF29 chromosome 22 open reading frame 29
C4ORF19 chromosome 4 open reading frame 19
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CLDN9 claudin 9
CLEC16A C-type lectin domain family 16, member A
CORO7 coronin 7
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELMO3 engulfment and cell motility 3
EPHA4 EPH receptor A4
FBXL15 F-box and leucine-rich repeat protein 15
FBXL2 F-box and leucine-rich repeat protein 2
FBXO46 F-box protein 46
FGL1 fibrinogen-like 1
FZD2 frizzled class receptor 2
GDAP2 ganglioside induced differentiation associated protein 2
GLS2 glutaminase 2 (liver, mitochondrial)
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AL histone cluster 1, H2al
HIST1H3B histone cluster 1, H3b
HOXA4 homeobox A4
HOXC10 homeobox C10
HOXC13 homeobox C13
HOXC8 homeobox C8
HPS6 Hermansky-Pudlak syndrome 6
IER3IP1 immediate early response 3 interacting protein 1
INF2 inverted formin, FH2 and WH2 domain containing
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF13B kinesin family member 13B
KIFC1 kinesin family member C1
LGALS4 lectin, galactoside-binding, soluble, 4
LIME1 Lck interacting transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MCOLN1 mucolipin 1
MMRN2 multimerin 2
MOSPD3 motile sperm domain containing 3
MVD mevalonate (diphospho) decarboxylase
NEK11 NIMA-related kinase 11
NR2F2 nuclear receptor subfamily 2, group F, member 2
NT5DC3 5'-nucleotidase domain containing 3
NTHL1 nth endonuclease III-like 1 (E. coli)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI1 peptidyl arginine deiminase, type I
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAQR6 progestin and adipoQ receptor family member VI
PARPBP PARP1 binding protein
PELP1 proline, glutamate and leucine rich protein 1
PLTP phospholipid transfer protein
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRR15L proline rich 15-like
PTPRU protein tyrosine phosphatase, receptor type, U
RAB26 RAB26, member RAS oncogene family
RBM42 RNA binding motif protein 42
RFPL3 ret finger protein-like 3
RGS16 regulator of G-protein signaling 16
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAA3P serum amyloid A3 pseudogene
SFT2D2 SFT2 domain containing 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SOBP sine oculis binding protein homolog (Drosophila)
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TMEM121 transmembrane protein 121
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAF5 TNF receptor-associated factor 5
TRIM45 tripartite motif containing 45
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
USP19 ubiquitin specific peptidase 19
VSIG10 V-set and immunoglobulin domain containing 10
ZNF248 zinc finger protein 248
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768
ZSCAN26 zinc finger and SCAN domain containing 26