5149715-890 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the 5149715-890 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ALCAM activated leukocyte cell adhesion molecule
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAG4 BCL2-associated athanogene 4
BCL7A B-cell CLL/lymphoma 7A
BTG2 BTG family, member 2
C1ORF159 chromosome 1 open reading frame 159
C2ORF54 chromosome 2 open reading frame 54
CASZ1 castor zinc finger 1
CD58 CD58 molecule
CLDN1 claudin 1
CRELD1 cysteine-rich with EGF-like domains 1
CRTC1 CREB regulated transcription coactivator 1
CTNS cystinosin, lysosomal cystine transporter
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DHODH dihydroorotate dehydrogenase (quinone)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EED embryonic ectoderm development
EPHB3 EPH receptor B3
ERO1L ERO1-like (S. cerevisiae)
ERP44 endoplasmic reticulum protein 44
FCMR Fc fragment of IgM receptor
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL1 four and a half LIM domains 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FNDC3A fibronectin type III domain containing 3A
FOXJ3 forkhead box J3
GSK3A glycogen synthase kinase 3 alpha
GSPT1 G1 to S phase transition 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMGN5 high mobility group nucleosome binding domain 5
HNMT histamine N-methyltransferase
HSPA12A heat shock 70kDa protein 12A
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INPP5J inositol polyphosphate-5-phosphatase J
IRF6 interferon regulatory factor 6
ITGB5 integrin, beta 5
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDM5A lysine (K)-specific demethylase 5A
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT13 keratin 13, type I
LIN7A lin-7 homolog A (C. elegans)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MSX1 msh homeobox 1
NEB nebulin
NEBL nebulette
OASL 2'-5'-oligoadenylate synthetase-like
OGFRL1 opioid growth factor receptor-like 1
PAX8 paired box 8
PCNX pecanex homolog (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKD3 protein kinase D3
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RNF43 ring finger protein 43
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUNDC3B RUN domain containing 3B
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SH2B3 SH2B adaptor protein 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMTN smoothelin
SOS2 son of sevenless homolog 2 (Drosophila)
SP1 Sp1 transcription factor
SPG20 spastic paraplegia 20 (Troyer syndrome)
TADA3 transcriptional adaptor 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TET3 tet methylcytosine dioxygenase 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TP53I11 tumor protein p53 inducible protein 11
TPI1 triosephosphate isomerase 1
TRIO trio Rho guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WRAP53 WD repeat containing, antisense to TP53
ZBTB6 zinc finger and BTB domain containing 6
ZNF16 zinc finger protein 16
ZNF222 zinc finger protein 222
ZNF37BP zinc finger protein 37B, pseudogene
ZNF473 zinc finger protein 473
ZNF787 zinc finger protein 787
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE5 adhesion G protein-coupled receptor E5
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALS2CL ALS2 C-terminal like
ANPEP alanyl (membrane) aminopeptidase
ASB8 ankyrin repeat and SOCS box containing 8
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
C14ORF132 chromosome 14 open reading frame 132
C14ORF93 chromosome 14 open reading frame 93
C5ORF45 chromosome 5 open reading frame 45
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CLCN6 chloride channel, voltage-sensitive 6
CLSTN2 calsyntenin 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CSPP1 centrosome and spindle pole associated protein 1
CUEDC1 CUE domain containing 1
DCAF16 DDB1 and CUL4 associated factor 16
DGAT1 diacylglycerol O-acyltransferase 1
DUSP8 dual specificity phosphatase 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
EXD3 exonuclease 3'-5' domain containing 3
FAM188A family with sequence similarity 188, member A
FBXW12 F-box and WD repeat domain containing 12
GMEB1 glucocorticoid modulatory element binding protein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR87 G protein-coupled receptor 87
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HOOK1 hook microtubule-tethering protein 1
HYI hydroxypyruvate isomerase (putative)
IGFLR1 IGF-like family receptor 1
INPP5K inositol polyphosphate-5-phosphatase K
IPO8 importin 8
KIAA0894 KIAA0894 protein
LIME1 Lck interacting transmembrane adaptor 1
LOC100272216 uncharacterized LOC100272216
LOC730101 uncharacterized LOC730101
LRRC49 leucine rich repeat containing 49
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MIS18BP1 MIS18 binding protein 1
MMP9 matrix metallopeptidase 9
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NRSN2 neurensin 2
PARD6A par-6 family cell polarity regulator alpha
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RANBP17 RAN binding protein 17
RAPSN receptor-associated protein of the synapse
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAMD9 sterile alpha motif domain containing 9
SNX15 sorting nexin 15
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMC5 transmembrane channel-like 5
TRIM52 tripartite motif containing 52
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP6NL USP6 N-terminal like
VAV1 vav 1 guanine nucleotide exchange factor
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XYLT2 xylosyltransferase II
YEATS2 YEATS domain containing 2
ZBTB48 zinc finger and BTB domain containing 48
ZNF134 zinc finger protein 134
ZNF160 zinc finger protein 160
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76