253J Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human bladder transitional cell carcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004796)
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84 genes mutated in the 253J cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADAM32 ADAM metallopeptidase domain 32
ADCK1 aarF domain containing kinase 1
AFF1 AF4/FMR2 family, member 1
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
ALPK1 alpha-kinase 1
ATR ATR serine/threonine kinase
BAG6 BCL2-associated athanogene 6
BRCA1 breast cancer 1, early onset
BRD2 bromodomain containing 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CDK11B cyclin-dependent kinase 11B
CDKL3 cyclin-dependent kinase-like 3
CHUK conserved helix-loop-helix ubiquitous kinase
CIITA class II, major histocompatibility complex, transactivator
CLTCL1 clathrin, heavy chain-like 1
DGKB diacylglycerol kinase, beta 90kDa
DST dystonin
EHBP1 EH domain binding protein 1
EIF4E eukaryotic translation initiation factor 4E
EP300 E1A binding protein p300
FGFR1OP FGFR1 oncogene partner
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCY2C guanylate cyclase 2C
HDAC6 histone deacetylase 6
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ILK integrin-linked kinase
INHBA inhibin, beta A
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGA10 integrin, alpha 10
KAT6B K(lysine) acetyltransferase 6B
LATS2 large tumor suppressor kinase 2
LETM2 leucine zipper-EF-hand containing transmembrane protein 2
LRP1 low density lipoprotein receptor-related protein 1
LRRK2 leucine-rich repeat kinase 2
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LZTR1 leucine-zipper-like transcription regulator 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MCM3AP-AS1 MCM3AP antisense RNA 1
MECOM MDS1 and EVI1 complex locus
MPL MPL proto-oncogene, thrombopoietin receptor
MSH3 mutS homolog 3
NCAM1 neural cell adhesion molecule 1
NEK3 NIMA-related kinase 3
NEK9 NIMA-related kinase 9
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIA nuclear factor I/A
NIPBL Nipped-B homolog (Drosophila)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRRX1 paired related homeobox 1
RPS6 ribosomal protein S6
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SSX4 synovial sarcoma, X breakpoint 4
STK31 serine/threonine kinase 31
TAOK3 TAO kinase 3
TEC tec protein tyrosine kinase
THBS3 thrombospondin 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM123 transmembrane protein 123
TRPS1 trichorhinophalangeal syndrome I
TRRAP transformation/transcription domain-associated protein
TSSK4 testis-specific serine kinase 4
TTN titin
VEGFC vascular endothelial growth factor C
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK