16-phenyltetranorprostaglandin E2-7509 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the 16-phenyltetranorprostaglandin E2-7509 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AFF1 AF4/FMR2 family, member 1
AMDHD2 amidohydrolase domain containing 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP3 aquaporin 3 (Gill blood group)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARPIN actin-related protein 2/3 complex inhibitor
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF60 chromosome 19 open reading frame 60
C1ORF95 chromosome 1 open reading frame 95
C6ORF47 chromosome 6 open reading frame 47
CCNO cyclin O
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDIP1 cell death-inducing p53 target 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEMIP cell migration inducing protein, hyaluronan binding
CROCC ciliary rootlet coiled-coil, rootletin
CSNK1E casein kinase 1, epsilon
CTSZ cathepsin Z
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DMTN dematin actin binding protein
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DST dystonin
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FA2H fatty acid 2-hydroxylase
FAM13A family with sequence similarity 13, member A
FAM212B family with sequence similarity 212, member B
FNDC3A fibronectin type III domain containing 3A
GPATCH3 G patch domain containing 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPG2 heparan sulfate proteoglycan 2
IL1RL1 interleukin 1 receptor-like 1
ISG20 interferon stimulated exonuclease gene 20kDa
KDM8 lysine (K)-specific demethylase 8
KLF13 Kruppel-like factor 13
KRT17 keratin 17, type I
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPP LIM domain containing preferred translocation partner in lipoma
LRRC23 leucine rich repeat containing 23
LRRN2 leucine rich repeat neuronal 2
LYPD3 LY6/PLAUR domain containing 3
MAP2K7 mitogen-activated protein kinase kinase 7
MAP7 microtubule-associated protein 7
MBD5 methyl-CpG binding domain protein 5
MECP2 methyl CpG binding protein 2
MED25 mediator complex subunit 25
MOCS1 molybdenum cofactor synthesis 1
MRPS12 mitochondrial ribosomal protein S12
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO9B myosin IXB
NPFFR1 neuropeptide FF receptor 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OSBPL10 oxysterol binding protein-like 10
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE8B phosphodiesterase 8B
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIDD1 p53-induced death domain protein 1
PKNOX1 PBX/knotted 1 homeobox 1
POU5F1B POU class 5 homeobox 1B
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
RAB3B RAB3B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP1 RAN binding protein 1
RANBP3 RAN binding protein 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPLP2 ribosomal protein, large, P2
RUNX3 runt-related transcription factor 3
S100P S100 calcium binding protein P
SCARB2 scavenger receptor class B, member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SMG7 SMG7 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAC SH3 and cysteine rich domain
STC1 stanniocalcin 1
SYT17 synaptotagmin XVII
TADA2A transcriptional adaptor 2A
TBC1D30 TBC1 domain family, member 30
TBCD tubulin folding cofactor D
TMEM53 transmembrane protein 53
TPMT thiopurine S-methyltransferase
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UBQLN4 ubiquilin 4
UNC5B unc-5 homolog B (C. elegans)
VASH1 vasohibin 1
VIPR2 vasoactive intestinal peptide receptor 2
WSB1 WD repeat and SOCS box containing 1
XYLT2 xylosyltransferase II
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR1 activin A receptor, type I
AIDA axin interactor, dorsalization associated
AMIGO2 adhesion molecule with Ig-like domain 2
ANAPC10 anaphase promoting complex subunit 10
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARMCX5 armadillo repeat containing, X-linked 5
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF62 chromosome 16 open reading frame 62
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3ORF52 chromosome 3 open reading frame 52
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CARD8 caspase recruitment domain family, member 8
CASD1 CAS1 domain containing 1
CBX4 chromobox homolog 4
CCDC109B coiled-coil domain containing 109B
CD302 CD302 molecule
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLDND1 claudin domain containing 1
CNN3 calponin 3, acidic
CRYZ crystallin, zeta (quinone reductase)
CTGF connective tissue growth factor
DMXL1 Dmx-like 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DPYD dihydropyrimidine dehydrogenase
EXOC5 exocyst complex component 5
F8 coagulation factor VIII, procoagulant component
FAM179B family with sequence similarity 179, member B
FAM188A family with sequence similarity 188, member A
FBXO5 F-box protein 5
FZD3 frizzled class receptor 3
FZD6 frizzled class receptor 6
GALT galactose-1-phosphate uridylyltransferase
GRPR gastrin-releasing peptide receptor
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC7 histone deacetylase 7
IFI6 interferon, alpha-inducible protein 6
INSIG2 insulin induced gene 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD3 potassium channel tetramerization domain containing 3
KIF1B kinesin family member 1B
KRT75 keratin 75, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LINC00260 long intergenic non-protein coding RNA 260
LMNB1 lamin B1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MED17 mediator complex subunit 17
MED4 mediator complex subunit 4
MYOZ3 myozenin 3
NAP1L3 nucleosome assembly protein 1-like 3
NCAPG2 non-SMC condensin II complex, subunit G2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NHLRC2 NHL repeat containing 2
P3H2 prolyl 3-hydroxylase 2
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PPCS phosphopantothenoylcysteine synthetase
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPF38B pre-mRNA processing factor 38B
PRR16 proline rich 16
PSAT1 phosphoserine aminotransferase 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RAI14 retinoic acid induced 14
RCOR3 REST corepressor 3
RGS20 regulator of G-protein signaling 20
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAI suppressor of cancer cell invasion
SCRN3 secernin 3
SEC24B SEC24 family member B
SELT selenoprotein T
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCE sarcoglycan, epsilon
SGMS1 sphingomyelin synthase 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TM2D3 TM2 domain containing 3
TMC5 transmembrane channel-like 5
TMEM230 transmembrane protein 230
TMEM242 transmembrane protein 242
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
WNT7A wingless-type MMTV integration site family, member 7A
YIPF5 Yip1 domain family, member 5
YPEL1 yippee-like 1 (Drosophila)
ZBTB10 zinc finger and BTB domain containing 10
ZDHHC13 zinc finger, DHHC-type containing 13
ZFAND1 zinc finger, AN1-type domain 1
ZNF124 zinc finger protein 124