15-deoxy-delta(12,14)-prostaglandin J2 Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A prostaglandin J derivative comprising prostaglandin J2 lacking the 15-hydroxy group and having C=C double bonds at the 12- and 14-positions. (Chemical Entities of Biological Interest Ontology, CHEBI_34159)
External Link http://ctdbase.org/detail.go?type=chem&acc=C097240
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Genes

81 genes/proteins interacting with the chemical 15-deoxy-delta(12,14)-prostaglandin J2 from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND3 cyclin D3
CCNE1 cyclin E1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
EGR1 early growth response 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLC glutamate-cysteine ligase, catalytic subunit
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
IFNG interferon, gamma
IL1B interleukin 1, beta
IL6 interleukin 6
INS insulin
JAK2 Janus kinase 2
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
LEP leptin
LIF leukemia inhibitory factor
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MED1 mediator complex subunit 1
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARB retinoic acid receptor, beta
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD2 SMAD family member 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
TNF tumor necrosis factor
TSHB thyroid stimulating hormone, beta
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase