15-delta prostaglandin J2-6990 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 15-delta prostaglandin J2-6990 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ATF3 activating transcription factor 3
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C1ORF61 chromosome 1 open reading frame 61
CBR3 carbonyl reductase 3
CCDC186 coiled-coil domain containing 186
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL5A1 collagen, type V, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
CYLD cylindromatosis (turban tumor syndrome)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOCK9 dedicator of cytokinesis 9
DTNA dystrobrevin, alpha
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB3 EPH receptor B3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45G growth arrest and DNA-damage-inducible, gamma
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLS glutaminase
HMOX1 heme oxygenase 1
HSPA12A heat shock 70kDa protein 12A
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL15RA interleukin 15 receptor, alpha
ITPKC inositol-trisphosphate 3-kinase C
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MALT1 MALT1 paracaspase
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MBD1 methyl-CpG binding domain protein 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED12 mediator complex subunit 12
MFAP2 microfibrillar-associated protein 2
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NAP1L2 nucleosome assembly protein 1-like 2
NDRG1 N-myc downstream regulated 1
NMT2 N-myristoyltransferase 2
OSGIN1 oxidative stress induced growth inhibitor 1
PAX5 paired box 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
REEP1 receptor accessory protein 1
RIT1 Ras-like without CAAX 1
RNF19B ring finger protein 19B
RRBP1 ribosome binding protein 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIX2 SIX homeobox 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SQSTM1 sequestosome 1
STYK1 serine/threonine/tyrosine kinase 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBCD tubulin folding cofactor D
TES testin LIM domain protein
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TTBK2 tau tubulin kinase 2
TXNRD1 thioredoxin reductase 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFAND5 zinc finger, AN1-type domain 5
ZNF10 zinc finger protein 10
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADCY6 adenylate cyclase 6
ANKRD28 ankyrin repeat domain 28
ANKRD36 ankyrin repeat domain 36
ASB9 ankyrin repeat and SOCS box containing 9
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BACE1 beta-site APP-cleaving enzyme 1
C5ORF45 chromosome 5 open reading frame 45
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMTA2 calmodulin binding transcription activator 2
CAPN1 calpain 1, (mu/I) large subunit
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBX7 chromobox homolog 7
CCDC25 coiled-coil domain containing 25
CCNE1 cyclin E1
CCNE2 cyclin E2
CEP131 centrosomal protein 131kDa
CISH cytokine inducible SH2-containing protein
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DSCAM Down syndrome cell adhesion molecule
ESRP2 epithelial splicing regulatory protein 2
EVL Enah/Vasp-like
FAM160B2 family with sequence similarity 160, member B2
FBXL15 F-box and leucine-rich repeat protein 15
FMO4 flavin containing monooxygenase 4
FUZ fuzzy planar cell polarity protein
GJA1 gap junction protein, alpha 1, 43kDa
GPR19 G protein-coupled receptor 19
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC13 homeobox C13
JMJD4 jumonji domain containing 4
KIFC1 kinesin family member C1
LAMA5 laminin, alpha 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LNPEP leucyl/cystinyl aminopeptidase
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MATK megakaryocyte-associated tyrosine kinase
MBTD1 mbt domain containing 1
MEIS1 Meis homeobox 1
MTCL1 microtubule crosslinking factor 1
MYO1E myosin IE
NCAPH non-SMC condensin I complex, subunit H
NPY1R neuropeptide Y receptor Y1
OTUD3 OTU deubiquitinase 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PACS1 phosphofurin acidic cluster sorting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PGP phosphoglycolate phosphatase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G10 phospholipase A2, group X
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAD54L RAD54-like (S. cerevisiae)
RANGRF RAN guanine nucleotide release factor
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RGS16 regulator of G-protein signaling 16
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPPLY3 ripply transcriptional repressor 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SHPK sedoheptulokinase
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STARD13 StAR-related lipid transfer (START) domain containing 13
SULF1 sulfatase 1
SUSD4 sushi domain containing 4
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TRAPPC12 trafficking protein particle complex 12
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN1 tetraspanin 1
TSPAN5 tetraspanin 5
WDR19 WD repeat domain 19
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZNF276 zinc finger protein 276
ZNF350 zinc finger protein 350
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF768 zinc finger protein 768
ZNF787 zinc finger protein 787