15-delta prostaglandin J2-6948 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 15-delta prostaglandin J2-6948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASF1A anti-silencing function 1A histone chaperone
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASTN2 astrotactin 2
ATF3 activating transcription factor 3
BANP BTG3 associated nuclear protein
BLVRA biliverdin reductase A
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C17ORF80 chromosome 17 open reading frame 80
CBR3 carbonyl reductase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CREM cAMP responsive element modulator
CYB5R1 cytochrome b5 reductase 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP13 dual specificity phosphatase 13
FAM129A family with sequence similarity 129, member A
FAM134B family with sequence similarity 134, member B
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GID4 GID complex subunit 4
GPATCH3 G patch domain containing 3
GRB10 growth factor receptor-bound protein 10
HEG1 heart development protein with EGF-like domains 1
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
IL15RA interleukin 15 receptor, alpha
IL1R1 interleukin 1 receptor, type I
ITM2C integral membrane protein 2C
KDM6A lysine (K)-specific demethylase 6A
LARP6 La ribonucleoprotein domain family, member 6
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP1B microtubule-associated protein 1B
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MMP19 matrix metallopeptidase 19
N4BP2L2 NEDD4 binding protein 2-like 2
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
PCNXL2 pecanex-like 2 (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PELO pelota homolog (Drosophila)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RIT1 Ras-like without CAAX 1
RNF19B ring finger protein 19B
SEC14L1 SEC14-like 1 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SH2B3 SH2B adaptor protein 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SQSTM1 sequestosome 1
STX16 syntaxin 16
STYK1 serine/threonine/tyrosine kinase 1
TES testin LIM domain protein
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIB3 tribbles pseudokinase 3
TUBA4A tubulin, alpha 4a
TXNRD1 thioredoxin reductase 1
ULBP2 UL16 binding protein 2
UNKL unkempt family zinc finger-like
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
ZFAND5 zinc finger, AN1-type domain 5
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACKR3 atypical chemokine receptor 3
ADCY6 adenylate cyclase 6
ARHGAP11A Rho GTPase activating protein 11A
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX1 armadillo repeat containing, X-linked 1
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BAMBI BMP and activin membrane-bound inhibitor
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C14ORF169 chromosome 14 open reading frame 169
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNE2 cyclin E2
CENPB centromere protein B, 80kDa
CEP72 centrosomal protein 72kDa
CISH cytokine inducible SH2-containing protein
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXORF56 chromosome X open reading frame 56
DKK1 dickkopf WNT signaling pathway inhibitor 1
E2F8 E2F transcription factor 8
EFNA1 ephrin-A1
EPHA4 EPH receptor A4
ERCC6L excision repair cross-complementation group 6-like
ERF Ets2 repressor factor
ESRP2 epithelial splicing regulatory protein 2
FEN1 flap structure-specific endonuclease 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUZ fuzzy planar cell polarity protein
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1D histone cluster 1, H1d
HOXC11 homeobox C11
HOXC13 homeobox C13
ICK intestinal cell (MAK-like) kinase
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF20A kinesin family member 20A
KIFC1 kinesin family member C1
LINC00115 long intergenic non-protein coding RNA 115
LMBR1L limb development membrane protein 1-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MANBA mannosidase, beta A, lysosomal
MCM10 minichromosome maintenance complex component 10
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NCAPH non-SMC condensin I complex, subunit H
NINL ninein-like
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PCP4 Purkinje cell protein 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS16 regulator of G-protein signaling 16
RGS19 regulator of G-protein signaling 19
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SHPK sedoheptulokinase
SLC12A9 solute carrier family 12, member 9
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPIDR scaffolding protein involved in DNA repair
STARD13 StAR-related lipid transfer (START) domain containing 13
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYTL2 synaptotagmin-like 2
TMEM104 transmembrane protein 104
TMEM110 transmembrane protein 110
TMEM184B transmembrane protein 184B
TPBG trophoblast glycoprotein
TRIP10 thyroid hormone receptor interactor 10
TROAP trophinin associated protein
TSSC4 tumor suppressing subtransferable candidate 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASH2 vasohibin 2
VAV3 vav 3 guanine nucleotide exchange factor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF512B zinc finger protein 512B
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF768 zinc finger protein 768